scholarly journals Bacterial toxicity of biomimetic green zinc oxide nanoantibiotic: insights into ZnONP uptake and nanocolloid–bacteria interface

2019 ◽  
Vol 8 (2) ◽  
pp. 246-261 ◽  
Author(s):  
Bilal Ahmed ◽  
Bushra Solanki ◽  
Almas Zaidi ◽  
Mohammad Saghir Khan ◽  
Javed Musarrat
Keyword(s):  
Zinc Oxide ◽  
Inhibitory Action ◽  
Zinc Ions ◽  
Bacterial Toxicity

Growth and biofilm inhibitory action of biomimetic green ZnONPs and dissolved zinc ions on a bacterial interface.

scholarly journals Mechanisms and effects of zinc oxide nanoparticle transformations on toxicity to zebrafish embryos

2021 ◽  
Author(s):  
Gyudong Lee ◽  
Byongcheun Lee ◽  
Ki-Tae Kim
Keyword(s):  
Zinc Oxide ◽  
Physicochemical Properties ◽  
Zebrafish Embryos ◽  
Zinc Ions ◽  
Zno Nps ◽  
Zinc Oxide Nanoparticle ◽  
Toxicity Reduction ◽  
Oxide Nanoparticle

Environmental transformations modify the physicochemical properties of ZnO NPs, modulate their ability to reduce zinc ions, and determine the degree of toxicity reduction in zebrafish embryos.

Autophagy-dependent release of zinc ions is critical for acute lung injury triggered by zinc oxide nanoparticles

2018 ◽  
Vol 12 (9) ◽  
pp. 1068-1091 ◽  
Author(s):  
Xuejun Jiang ◽  
Qianghu Tang ◽  
Jun Zhang ◽  
Hong Wang ◽  
Lulu Bai ◽  
...  
Keyword(s):  
Zinc Oxide ◽  
Acute Lung Injury ◽  
Lung Injury ◽  
Zinc Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Zinc Ions

scholarly journals Organic Zinc Salts as Pro-Ecological Activators for Sulfur Vulcanization of Styrene–Butadiene Rubber

Polymers ◽  
2019 ◽  
Vol 11 (10) ◽  
pp. 1723 ◽  
Author(s):  
Magdalena Maciejewska ◽  
Anna Sowińska ◽  
Judyta Kucharska
Keyword(s):  
Zinc Oxide ◽  
Styrene Butadiene Rubber ◽  
Butadiene Rubber ◽  
Zinc Ions ◽  
Organic Zinc ◽  
Rubber Compounds ◽  
Curing Characteristics ◽  
Sulfur Vulcanization ◽  
Zinc Salts ◽  
Styrene Butadiene

Organic zinc salts and complexes were applied as activators for sulfur vulcanization of styrene–butadiene elastomer (SBR) in order to reduce the content of zinc ions in rubber compounds as compared with conventionally used zinc oxide. In this article, the effects of different organic zinc activators on the curing characteristics, crosslink densities, and mechanical properties of SBR as well as the aging resistance and thermal behavior of vulcanizates are discussed. Organic zinc salts seem to be good substitutes for zinc oxide as activators for sulfur vulcanization of SBR rubber, without detrimental effects to the vulcanization time and temperature. Moreover, vulcanizates containing organic zinc salts exhibit higher tensile strength and better damping properties than vulcanizate crosslinked with zinc oxide. The application of organic zinc activators allows the amount of zinc ions in SBR compounds to be reduced by 70–90 wt % compared to vulcanizate with zinc oxide. This is very important for ecological reasons, since zinc oxide is classified as being toxic to aquatic species.

Toxicokinetics of zinc-oxide nanoparticles and zinc ions in the earthworm Eisenia andrei

2017 ◽  
Vol 143 ◽  
pp. 151-158 ◽  
Author(s):  
Zuzanna M. Świątek ◽  
Cornelis A.M. van Gestel ◽  
Agnieszka J. Bednarska
Keyword(s):  
Zinc Oxide ◽  
Zinc Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Zinc Ions ◽  
Eisenia Andrei

scholarly journals Inhibitory action of two zinc oxide sources on the ex vivo growth of porcine small intestine bacteria

2012 ◽  
Vol 90 (suppl_4) ◽  
pp. 334-336 ◽  
Author(s):  
W. Vahjen ◽  
J. Zentek ◽  
S. Durosoy
Keyword(s):  
Zinc Oxide ◽  
Small Intestine ◽  
Inhibitory Action ◽  
Ex Vivo

Characterizing the inhibitory action of zinc oxide nanoparticles on allergic-type mast cell activation

2015 ◽  
Vol 66 (2) ◽  
pp. 139-146 ◽  
Author(s):  
B.N. Feltis ◽  
A. Elbaz ◽  
P.F.A. Wright ◽  
G.A. Mackay ◽  
T.W. Turney ◽  
...  
Keyword(s):  
Zinc Oxide ◽  
Mast Cell ◽  
Zinc Oxide Nanoparticles ◽  
Inhibitory Action ◽  
Cell Activation ◽  
Mast Cell Activation ◽  
Oxide Nanoparticles

scholarly journals Inhibition of hemolytic activity of Streptococcus pyogenes in mechanisms of antibacterial action of zinc ions

2019 ◽  
pp. 16-23
Author(s):  
S. B. Cheknev ◽  
E. I. Vostrova ◽  
M. A. Sarycheva ◽  
A. V. Vostrov
Keyword(s):  
Growth Inhibition ◽  
Streptococcus Pyogenes ◽  
Hemolytic Activity ◽  
Inhibitory Action ◽  
Bacterial Culture ◽  
Copper Ions ◽  
Zinc Ions ◽  
Bacterial Cells ◽  
Bacterial Cultures ◽  
Culture Growth

Aim. The work was performed with the purpose to study a hemolytic activity in the culture of S.pyogenes under the inhibitory action of millimolar concentrations of zinc ions.Materials and methods. Suspensions of S.pyogenes bacteria which contained 108 CFU/ml were sown by the lawns into the standard Petri dishes coated with the supplemented Blood Nutrient Agar. 30 min later the salt solutions of zinc or copper which contained the metals at the concentrations ranged between 5 x 10-3 M to 5 x 10-1 M were added by the 5 μl drops on the surfaces of the lawns with use of 36-channel stamp replicator. Then the dishes with bacterial cultures were incubated for 24 hrs at 37°C followed by measuring diameter of the area of culture growth inhibition and of the area of inhibition of hemolysis. The study was performed with use of controls towards measuring the state of bacterial cells obtained from different zones of the areas.Results. In presence of the zinc ions concentrations ranged between 50 to 500 mM the area of the growth inhibition of S.pyogenes was surrounded on the lawn of the bacterial culture by the area of the inhibition of hemolysis where the growth inhibition of S.pyogenes was not registered. Copper ions did not form such an area of the hemolysis inhibition.Conclusion. Inhibitory action of zinc ions on the hemolytic S.pyogenes activity in the culture seems to be specific and reversible, and is discussed in a context of the antivirulent zinc ions properties.

scholarly journals Evaluation of the Antibacterial Activity and Cell Response for 3D-Printed Polycaprolactone/Nanohydroxyapatite Scaffold with Zinc Oxide Coating

Polymers ◽  
2020 ◽  
Vol 12 (10) ◽  
pp. 2193
Author(s):  
Yong Sang Cho ◽  
Hee-Kyeong Kim ◽  
Min-Soo Ghim ◽  
Myoung Wha Hong ◽  
Young Yul Kim ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Zinc Oxide ◽  
Antibacterial Activity ◽  
Cell Response ◽  
Oxide Coating ◽  
Compressive Modulus ◽  
Bacterial Activity ◽  
Zinc Ions ◽  
3D Printed

Among 3D-printed composite scaffolds for bone tissue engineering, researchers have been attracted to the use of zinc ions to improve the scaffold’s anti-bacterial activity and prevent surgical site infection. In this study, we assumed that the concentration of zinc ions released from the scaffold will be correlated with the thickness of the zinc oxide coating on 3D-printed scaffolds. We investigated the adequate thickness of zinc oxide coating by comparing different scaffolds’ characteristics, antibacterial activity, and in vitro cell response. The scaffolds’ compressive modulus decreased as the zinc oxide coating thickness increased (10, 100 and 200 nm). However, the compressive modulus of scaffolds in this study were superior to those of other reported scaffolds because our scaffolds had a kagome structure and were made of composite material. In regard to the antibacterial activity and in vitro cell response, the in vitro cell proliferation on scaffolds with a zinc oxide coating was higher than that of the control scaffold. Moreover, the antibacterial activity of scaffolds with 100 or 200 nm-thick zinc oxide coating on Escherichia coli was superior to that of other scaffolds. Therefore, we concluded that the scaffold with a 100 nm-thick zinc oxide coating was the most appropriate scaffold to use as a bone-regenerating scaffold, given its mechanical property, its antibacterial activity, and its in vitro cell proliferation.

scholarly journals Recent Advances in Zinc Oxide Nanostructures with Antimicrobial Activities

2020 ◽  
Vol 21 (22) ◽  
pp. 8836
Author(s):  
Yuchao Li ◽  
Chengzhu Liao ◽  
Sie Chin Tjong
Keyword(s):  
Antimicrobial Activity ◽  
Zinc Oxide ◽  
Visible Light ◽  
Plant Extracts ◽  
Hexagonal Lattice ◽  
Zinc Salt ◽  
Cellular Respiration ◽  
Zinc Ions ◽  
Zno Nanostructures ◽  
Zno Nanomaterials

This article reviews the recent developments in the synthesis, antibacterial activity, and visible-light photocatalytic bacterial inactivation of nano-zinc oxide. Polycrystalline wurtzite ZnO nanostructures with a hexagonal lattice having different shapes can be synthesized by means of vapor-, liquid-, and solid-phase processing techniques. Among these, ZnO hierarchical nanostructures prepared from the liquid phase route are commonly used for antimicrobial activity. In particular, plant extract-mediated biosynthesis is a single step process for preparing nano-ZnO without using surfactants and toxic chemicals. The phytochemical molecules of natural plant extracts are attractive agents for reducing and stabilizing zinc ions of zinc salt precursors to form green ZnO nanostructures. The peel extracts of certain citrus fruits like grapefruits, lemons and oranges, acting as excellent chelating agents for zinc ions. Furthermore, phytochemicals of the plant extracts capped on ZnO nanomaterials are very effective for killing various bacterial strains, leading to low minimum inhibitory concentration (MIC) values. Bioactive phytocompounds from green ZnO also inhibit hemolysis of Staphylococcus aureus infected red blood cells and inflammatory activity of mammalian immune system. In general, three mechanisms have been adopted to explain bactericidal activity of ZnO nanomaterials, including direct contact killing, reactive oxygen species (ROS) production, and released zinc ion inactivation. These toxic effects lead to the destruction of bacterial membrane, denaturation of enzyme, inhibition of cellular respiration and deoxyribonucleic acid replication, causing leakage of the cytoplasmic content and eventual cell death. Meanwhile, antimicrobial activity of doped and modified ZnO nanomaterials under visible light can be attributed to photogeneration of ROS on their surfaces. Thus particular attention is paid to the design and synthesis of visible light-activated ZnO photocatalysts with antibacterial properties

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