scholarly journals Pharmacognostic and pharmacological evaluation ofEulaliopsis binataplant extracts by measuringin vitro/in vivosafety profile and anti-microbial potential

2018 ◽  
Vol 7 (3) ◽  
pp. 454-464
Author(s):  
Vinod Kumar ◽  
Arun K. Sharma ◽  
Satyendra K. Rajput ◽  
Mahesh Pal ◽  
Neerupma Dhiman
Keyword(s):  
Phytochemical Screening ◽  
Pharmacological Evaluation ◽  
Eulaliopsis Binata ◽  
Toxicological Profile ◽  
Microbial Potential

Present investigation emphasizes the pharmacognostic and phytochemical screening ofEulaliopsis binataextracts as well as their toxicological profile and anti-bacterial potential.

Phytochemical screening and acute oral toxicity study of Coldenia procumbens and Mukia maderaspatana whole-plant

2020 ◽  
Vol 9 (2) ◽  
pp. 16-31
Author(s):  
Ramachandran K ◽  
Venketnarayanan R ◽  
Rajesh Yadav ◽  
Suresh R ◽  
Sumitra Devkota
Keyword(s):  
Side Effects ◽  
Cancer Cells ◽  
Essential Role ◽  
Chemical Compounds ◽  
Acute Oral Toxicity ◽  
Lead Compound ◽  
Phytochemical Screening ◽  
Oral Toxicity ◽  
Whole Plant ◽  
Toxicological Profile

Usage of drugs to stop the growth of cancer cells both by killing the cancer cells or by stopping them from dividing is known as chemotherapy. Even though so many anticancer drugs are available in the market, there are many side effects of these drugs and therefore, the patient requires secondary palliative care. The way the chemotherapy is given depends on the type and stage of the cancer being treated. It plays an essential role in the discovery of lead compound for the development of conventional drugs. Plant herbs have non-toxic side effects. The plant and (L) M. possess chemical compounds that show antioxidant and anticancer activity. (L) M. , before its clinical usage, through the toxicological profile, was determined on the crude extracts as well as on isolated compounds to confirm the safety of the drug.

PHYTOCHEMICAL SCREENING AND LARVICIDAL EFFECT EVALUATION OF AZADIRACHTA INDICA (L) LEAF EXTRACT ON DERMESTES MACULATUS (DE GEER, 1774) INFESTATION OF SMOKED CLARIAS GARIEPINUS (BURCHELL, 1822)

2020 ◽  
Vol 4 (2) ◽  
pp. 41-45
Author(s):  
Sadam Sulaiman Indabo ◽  
Rufai Zakari
Keyword(s):  
Azadirachta Indica ◽  
Leaf Extract ◽  
Standard Procedure ◽  
Clarias Gariepinus ◽  
Phytochemical Screening ◽  
Range Finding ◽  
Dermestes Maculatus ◽  
Randomized Design ◽  
Fish Samples ◽  
Initial Source

Dermestes maculatus is a major pest of stored fish in Nigeria, fish is preserved with highly persistent synthetic chemicals. There have been an increasing effort at developing plant-based toxicants that are environmentally friendly. Therefore, this study was conducted to screen the leaf extract of Azadirachta indica for phytochemical constituents. The efficacy of the methanolic leaf extract of the plant against D. maculatus was also evaluated. The leaves of A. indica were obtained, processed and taken to laboratory for methanolic extraction. Phytochemical screening was carried out to identify saponins, flavonoids, alkaloids, tannins, steroids, cardiac glycosides, glycosides, triterpenes and carbohydrates using standard procedure.  Both clean and infested samples of smoke-dried Clarias gariepinus were purchased from Sabon Gari Market, Zaria. The infested samples were used as initial source of D. maculatus larvae. Range finding test was carried out prior to the bioassay. During the bioassay, clean un-infested fish samples were weighed and introduced into kilner jars and respective dosages of 0.2g, 0.4g, 0.6g and 0.8g of extract were added. Another set of fish samples without the extract were maintained as control. The experiment was arranged in Completely Randomized Design with three replicates. Fifteen larvae of D. maculatus were introduced into both treated and control containers and covered. Mortality was recorded after 24, 48, 72 and 96 hours. Data obtained revealed an increase in mortality with increasing dose and time. Mortality ranged from 1.67 to 11.00. Therefore, leaf extract of A. indica should be incorporated in the development of larvicide against D. maculatus.   

Phytochemical screening for identification of bioactive compounds of Lantana camara Linn. (Verbenaceae) responsible for larvicidal action against Aedes triseriatus Say, 1823 (Diptera : Culicidae)

ENTOMON ◽  
2019 ◽  
Vol 44 (2) ◽  
pp. 117-126
Author(s):  
Rhitayu Chakraborti ◽  
Probir Kumar Bandyopadhyay
Keyword(s):  
Ethyl Acetate ◽  
Bioactive Compounds ◽  
Active Ingredient ◽  
Crude Extract ◽  
Ethyl Acetate Extract ◽  
Lantana Camara ◽  
Mosquito Larvae ◽  
Aedes Triseriatus ◽  
Phytochemical Screening ◽  
Lc50 Value

Study to assess the larvicidal property of Lantana camara leaves against Aedes triseriatus larvae found that the ethyl acetate extract had profound larvicidal action with the crude extract having a LC50 value of 409.831ppm. GC-MS analysis of the ethyl acetate extract confirmed the presence of twenty-one compounds out of which beta-caryophyllene covered the highest percentage of the chromatogram area. Further tests with beta-caryophyllene against the mosquito larvae proved it to be the active ingredient of L. Camara with a LC50 value of 104.243ppm.

Sign in / Sign up

Export Citation Format

Share Document