A novel strategy to synthesize anisotropic SmCo5 particles from Co/Sm(OH)3 composites with special morphology

2018 ◽  
Vol 6 (31) ◽  
pp. 8522-8527 ◽  
Author(s):  
Chenglin Li ◽  
Qiong Wu ◽  
Zhenhui Ma ◽  
Huanhuan Xu ◽  
Liying Cong ◽  
...  
Keyword(s):  
Single Crystal ◽  
New Strategy ◽  
Special Morphology ◽  
Novel Strategy ◽  
Reductive Annealing

In this study, we report a new strategy for preparing magnetically anisotropic SmCo5 single crystal particles by reductive annealing of precursors with specially designed nanostructures.

scholarly journals Elimination of Ethylene from Cyclobutyl Groups Characterised by X-ray Crystallography in a Metal-Organic Framework Matrix

2020 ◽  
Author(s):  
Adil Alkas ◽  
Laurine E. S. Friche ◽  
Shikeale N. Harris ◽  
Shane G. Telfer
Keyword(s):  
Single Crystal ◽  
Metal Organic Framework ◽  
Synthetic Methods ◽  
Site Isolation ◽  
X Ray Crystallography ◽  
Structural Details ◽  
New Strategy ◽  
Metal Organic ◽  
Novel Strategy ◽  
Organic Framework

<p>We herein describe a series of breakthroughs in synthetic and structural chemistry. We have developed a novel strategy for the preparation and atomic-level characterisation of aromatic compounds with vinyl functional groups. Such compounds are highly sought after since they make exceptional polymers. Until now, however, deliberate synthetic methods and precise structural details have eluded researchers. We addressed this challenge by using a metal-organic framework as a matrix to isolate the vinyl groups. Cyclobutyl rings serve as synthetic precursors. The expulsion of ethylene from them delivers the desired compounds. This transformation is unprecedented in the literature. The framework is unperturbed by the high temperature required for thermolysis, which itself is a startling observation. We further show how the inherent reactivity of the vinyl groups can be harnessed to deliver addition products in quantitative yields. The two transformations take place in a single-crystal-to-single-crystal manner without changing the overall network structure of the parent framework. This manuscript defines a new strategy for preparing and studying an important class of compound using site-isolation in a framework matrix. It will thus appeal to synthetic chemists, materials scientists and crystallographers. Looking ahead, there are opportunities for the strategy to be extended to related compounds to produce other sought-after targets.</p>

scholarly journals Elimination of Ethylene from Cyclobutyl Groups Characterised by X-ray Crystallography in a Metal-Organic Framework Matrix

2020 ◽  
Author(s):  
Adil Alkas ◽  
Laurine E. S. Friche ◽  
Shikeale N. Harris ◽  
Shane G. Telfer
Keyword(s):  
Single Crystal ◽  
Metal Organic Framework ◽  
Synthetic Methods ◽  
Site Isolation ◽  
X Ray Crystallography ◽  
Structural Details ◽  
New Strategy ◽  
Metal Organic ◽  
Novel Strategy ◽  
Organic Framework

<p>We herein describe a series of breakthroughs in synthetic and structural chemistry. We have developed a novel strategy for the preparation and atomic-level characterisation of aromatic compounds with vinyl functional groups. Such compounds are highly sought after since they make exceptional polymers. Until now, however, deliberate synthetic methods and precise structural details have eluded researchers. We addressed this challenge by using a metal-organic framework as a matrix to isolate the vinyl groups. Cyclobutyl rings serve as synthetic precursors. The expulsion of ethylene from them delivers the desired compounds. This transformation is unprecedented in the literature. The framework is unperturbed by the high temperature required for thermolysis, which itself is a startling observation. We further show how the inherent reactivity of the vinyl groups can be harnessed to deliver addition products in quantitative yields. The two transformations take place in a single-crystal-to-single-crystal manner without changing the overall network structure of the parent framework. This manuscript defines a new strategy for preparing and studying an important class of compound using site-isolation in a framework matrix. It will thus appeal to synthetic chemists, materials scientists and crystallographers. Looking ahead, there are opportunities for the strategy to be extended to related compounds to produce other sought-after targets.</p>

Cascade photocaging of diazeniumdiolate: a novel strategy for one and two photon triggered uncaging with real time reporting

2017 ◽  
Vol 53 (68) ◽  
pp. 9470-9473 ◽  
Author(s):  
Krishna Kalyani Behara ◽  
Y. Rajesh ◽  
Yarra Venkatesh ◽  
Bhaskar Rao Pinninti ◽  
Mahitosh Mandal ◽  
...  
Keyword(s):  
Real Time ◽  
Two Photon ◽  
New Strategy ◽  
Novel Strategy

We report a new strategy, viz. cascade photocaging, for protecting diethylamine diazeniumdiolate (O2-position), a light sensitive molecule.

scholarly journals New Strategy for Analog Circuit Performance Evaluation under Disturbance and Fault Value

2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
Aihua Zhang ◽  
Yongchao Wang ◽  
Chen Chen ◽  
Hamid Reza Karimi
Keyword(s):  
Performance Evaluation ◽  
Support Vector Regression ◽  
Analog Circuit ◽  
Support Vector ◽  
Training Set ◽  
Circuit Performance ◽  
New Strategy ◽  
Indirect Evaluation ◽  
Novel Strategy ◽  
Fuzzy Learning

Focus on this issue of disturbance and fault value is inevitable in data collection about analog circuit. A novel strategy is developed for analog circuit online performance evaluation based on fuzzy learning and double weighted support vector machine (DWMK-FSVM). First, the double weighted support vector regression machine is employed to be the indirect evaluation means, relied on the college analog electronic technology experiment to evaluate analog circuit. Second, the superiority of fuzzy learning also is addressed to realize active suppression to the fault values and disturbance parameters. Moreover, the multikernel RBF is employed by support vector regression machine to realize more flexibility online such as the bandwidths tuning. Numerical results, supported by the college analog circuit experiments, adopted OTL performance eight indexes, which were obtained via precision instrument evaluation in two years to construct training set and are then to be evaluated online based on DWMK-FSVM. Simulation results presented not only highlight precision of the evaluation strategy derived here but also illustrate its great robustness.

A New Strategy to Inhibit of Stray Grain Formation During Laser Directed Solidification of Single Crystal Superalloys

2021 ◽  
Author(s):  
Jiawei Wang ◽  
Huaming Wang ◽  
Kangjie Li ◽  
Bo Zhang ◽  
Meiling Zhang ◽  
...  
Keyword(s):  
Single Crystal ◽  
Grain Formation ◽  
New Strategy ◽  
Stray Grain

Consistent gene signature of schizophrenia identified by a novel feature selection strategy from comprehensive sets of transcriptomic data

2019 ◽  
Vol 21 (3) ◽  
pp. 1058-1068 ◽  
Author(s):  
Qingxia Yang ◽  
Bo Li ◽  
Jing Tang ◽  
Xuejiao Cui ◽  
Yunxia Wang ◽  
...  
Keyword(s):  
Feature Selection ◽  
Current Medical Research ◽  
Gene Signature ◽  
Selection Strategy ◽  
Selection Methods ◽  
Transcriptomic Data ◽  
New Strategy ◽  
Consensus Scoring ◽  
Novel Strategy ◽  
Gene Rank

Abstract The etiology of schizophrenia (SCZ) is regarded as one of the most fundamental puzzles in current medical research, and its diagnosis is limited by the lack of objective molecular criteria. Although plenty of studies were conducted, SCZ gene signatures identified by these independent studies are found highly inconsistent. As one of the most important factors contributing to this inconsistency, the feature selection methods used currently do not fully consider the reproducibility among the signatures discovered from different datasets. Therefore, it is crucial to develop new bioinformatics tools of novel strategy for ensuring a stable discovery of gene signature for SCZ. In this study, a novel feature selection strategy (1) integrating repeated random sampling with consensus scoring and (2) evaluating the consistency of gene rank among different datasets was constructed. By systematically assessing the identified SCZ signature comprising 135 differentially expressed genes, this newly constructed strategy demonstrated significantly enhanced stability and better differentiating ability compared with the feature selection methods popular in current SCZ research. Based on a first-ever assessment on methods’ reproducibility cross-validated by independent datasets from three representative studies, the new strategy stood out among the popular methods by showing superior stability and differentiating ability. Finally, 2 novel and 17 previously reported transcription factors were identified and showed great potential in revealing the etiology of SCZ. In sum, the SCZ signature identified in this study would provide valuable clues for discovering diagnostic molecules and potential targets for SCZ.

A micron-scale laminar MAPbBr3 single crystal for an efficient and stable perovskite solar cell

2017 ◽  
Vol 53 (37) ◽  
pp. 5163-5166 ◽  
Author(s):  
Hua-Shang Rao ◽  
Bai-Xue Chen ◽  
Xu-Dong Wang ◽  
Dai-Bin Kuang ◽  
Cheng-Yong Su
Keyword(s):  
Solar Cell ◽  
Single Crystal ◽  
Perovskite Solar Cell ◽  
Novel Strategy

A novel strategy is used to prepare a MAPbBr3 single-crystal with a controllable thickness of 16 μm and a size of 6 × 8 mm.

scholarly journals New Strategy for Inducing Surface Anisotropy in Polyimide Films for Nematics Orientation in Display Applications

Nanomaterials ◽  
2021 ◽  
Vol 11 (11) ◽  
pp. 3107
Author(s):  
Elena-Luiza Epure ◽  
Iuliana Stoica ◽  
Raluca Marinica Albu ◽  
Camelia Hulubei ◽  
Andreea Irina Barzic
Keyword(s):  
Liquid Crystals ◽  
Surface Anisotropy ◽  
Polyimide Films ◽  
Alignment Layer ◽  
Display Devices ◽  
Force Microscopy ◽  
Atomic Force ◽  
New Strategy ◽  
Great Relevance ◽  
Novel Strategy

The operability of liquid crystal displays is strongly impacted by the orientation aspects of nematics, which in turn are affected by the alignment layer surface features. In this work, two polyimide (PI) structures are obtained based on a cycloaliphatic dianhydride and aromatic or aliphatic diamines with distinct flexibility. The attained PI films have high transmittance (T) for visible radiations, i.e., at 550 nm T > 80%. Here, a novel strategy for creating surface anisotropy in the samples that combines rubbing with a cloth and stretching via pressing is reported. Birefringence and atomic force microscopy (AFM) scans reveal that the generated orientation of the chains is affected by the chemical structure of the polymer and order of the steps involved in the surface treatment. Molecular modeling computations and wettability tests show that the PI structure and produced surface topography are competitive factors, which are impacting the intensity of the interactions with the nematic liquid crystals. The achieved results are of great relevance for designing of reliable display devices with improved uniform orientation of liquid crystals.

A unique synthesis of rare-earth-Co-based single crystal particles by “self-aligned” Co nano-arrays

Nanoscale ◽  
2020 ◽  
Vol 12 (26) ◽  
pp. 13958-13963 ◽  
Author(s):  
Qiong Wu ◽  
Liying Cong ◽  
Ming Yue ◽  
Chenglin Li ◽  
Zhenhui Ma ◽  
...  
Keyword(s):  
Rare Earth ◽  
Single Crystal ◽  
Reductive Annealing

Rare-earth-Co-based single crystal particles were synthesized by reductive annealing of “self-aligned” CoNRs@Sm2O3 nano-arrays without stabilizer coating.

Ultrasound Mediated Drug-Loaded Nanoparticles Crossing Cell Membranes as a New Strategy to Reverse Multidrug Resistance In Human Leukemia Cell Line K562/A02

Blood ◽  
2010 ◽  
Vol 116 (21) ◽  
pp. 3969-3969
Author(s):  
Bao-An Chen ◽  
Hai-jun Zhang ◽  
Xue-mei Wang ◽  
Hui Jiang ◽  
Chong Gao ◽  
...  
Keyword(s):  
Cell Membranes ◽  
Drug Carrier ◽  
Leukemia Cell ◽  
Leukemia Cell Line ◽  
Human Leukemia ◽  
Cathodic Current ◽  
Tio2 Nps ◽  
New Strategy ◽  
Human Leukemia Cell Line ◽  
Novel Strategy

Abstract Abstract 3969 Objective: Although many strategies have been explored to overcome the multidrug resistance (MDR) in leukemia which has rendered many currently available chemotherapeutic drugs ineffective, the results have been disappointing to the obstacle. The aim of this study was to investigate whether the new strategy of combining drug-loaded nanoparticles (Nps) and ultrasound (US) would show useful effects on the reversal of MDR in human leukemia cell line K562/A02. Methods: In this study, daunorubicin (DNR), a frequently chemotherapeutic agent known to cause DNA damage and induce apoptosis and cell death, was loaded on the TiO2 Nps which is chemically stable, environmental friendly, and shows weak or non cytotoxic to apply as the nano-drug carrier. The MDR leukemia K562/A02 cells were treated with the DNR-loaded TiO2 Nps drug carrier and US exposure. Then, we examined the effectiveness of delivering DNR into the MDR leukemia K562/A02 cells with the electrochemical studies, observed the bio-effects on the cell viability by MTT assays, investigated the induced apoptosis, and assessed the reversal ability and the mechanism of MDR by combining the drug-loaded Nps and US. Results: We observed good biocompatibility of the therapeutic approach. When the K562/A02 cells were incubated with DNR only, the cathodic current decreased by only 10% normalized to the DNR (10 μg/mL) standard, indicating less DNR was absorbed by the MDR cells. The cathodic current decreased by 39% and 63% in the presence of US or DNR-loaded TiO2 Nps, respectively. In comparison, when the cells were treated by the novel strategy of US mediated drug-loaded Nps crossing cell membranes, the cathodic current of DNR in the supernatant decreased greatly by 82% and became the minimal, which suggesting the least amount of DNR remained outside the MDR cells in this case and the largest uptake into the cells by this new strategy. These observations demonstrated that the remarkable synergistic effect of the novel strategy facilitated the accumulation of DNR in the MDR K562/A02 cells. In addition, our MTT assay illustrated comparative sensitization of the MDR K562/A02 cells under the treatment of US or drug-loaded Nps, but especially enhanced effect by combining drug-loaded Nps and US. The resisting fold of the MDR leukemia K562/A02 became obviously lower, decreasing from 58.71 to 16.69. The fresh evidence from caspase-3 immunocytochemistry demonstrated that the strategy could induce the apoptosis in the cells as well. Conclusion: It was therefore concluded that the strategy could have good reversal ability of MDR in tumor. These findings reveal that the reversal of MDR in tumor by US mediated drug-loaded Nps crossing cell membranes could represent promising approach in cancer therapy. Disclosures: No relevant conflicts of interest to declare.

Sign in / Sign up

Export Citation Format

Share Document