Injectable amine functionalized graphene and chondroitin sulfate hydrogel with potential for cartilage regeneration

2019 ◽  
Vol 7 (15) ◽  
pp. 2442-2453 ◽  
Author(s):  
Caoxin Tang ◽  
Brian D. Holt ◽  
Zoe M. Wright ◽  
Anne M. Arnold ◽  
Alexandra C. Moy ◽  
...  

Chemically functionalized graphene covalently reactsin situwith chondroitin sulfate to form an enhanced, injectable hydrogel for potential cartilage therapy.

2021 ◽  
Author(s):  
Xiaolin Li ◽  
Qian Xu ◽  
Melissa Johnson ◽  
Xi Wang ◽  
Jing Lyu ◽  
...  

Chondroitin sulfate (CS), as a popular material for cartilage tissue engineering scaffolds, has been extensively studied and reported for its safety and excellent biocompatibility. However, the rapid degradation of pure...


2015 ◽  
Vol 66 ◽  
pp. 129-135 ◽  
Author(s):  
Satish K. Tuteja ◽  
Manil Kukkar ◽  
C.R. Suri ◽  
A.K. Paul ◽  
Akash Deep

Author(s):  
Vikas V. Gaikwad ◽  
Abasaheb B. Patil ◽  
Madhuri V. Gaikwad

Scaffolds are used for drug delivery in tissue engineering as this system is a highly porous structure to allow tissue growth.  Although several tissues in the body can regenerate, other tissue such as heart muscles and nerves lack regeneration in adults. However, these can be regenerated by supplying the cells generated using tissue engineering from outside. For instance, in many heart diseases, there is need for heart valve transplantation and unfortunately, within 10 years of initial valve replacement, 50–60% of patients will experience prosthesis associated problems requiring reoperation. This could be avoided by transplantation of heart muscle cells that can regenerate. Delivery of these cells to the respective tissues is not an easy task and this could be done with the help of scaffolds. In situ gel forming scaffolds can also be used for the bone and cartilage regeneration. They can be injected anywhere and can take the shape of a tissue defect, avoiding the need for patient specific scaffold prefabrication and they also have other advantages. Scaffolds are prepared by biodegradable material that result in minimal immune and inflammatory response. Some of the very important issues regarding scaffolds as drug delivery systems is reviewed in this article.


2021 ◽  
Author(s):  
Shankar S. Narwade ◽  
Shivsharan M. Mali ◽  
Bhaskar R. Sathe

A study on the in situ decoration of ethylenediamine (EDA) on acid functionalized multi-walled carbon nanotubes (O-MWCNTs) for overall water splitting reactions at all pH as an efficient and inexpensive metal-free multifunctional electrocatalyst.


2016 ◽  
Vol 56 (11) ◽  
pp. 1221-1228 ◽  
Author(s):  
Suman Chhetri ◽  
Pranab Samanta ◽  
Naresh Chandra Murmu ◽  
Suneel Kumar Srivastava ◽  
Tapas Kuila

2013 ◽  
Vol 248-249 ◽  
pp. 322-328 ◽  
Author(s):  
Kavita Sablok ◽  
Vijayender Bhalla ◽  
Priyanka Sharma ◽  
Roohi Kaushal ◽  
Shilpa Chaudhary ◽  
...  

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