Visualizing cellular sodium hydrosulfite (Na2S2O4) using azo-based fluorescent probes with a high signal-to-noise ratio

2019 ◽  
Vol 7 (5) ◽  
pp. 730-733 ◽  
Author(s):  
Baoli Dong ◽  
Wenhui Song ◽  
Xiuqi Kong ◽  
Nan Zhang ◽  
Weiying Lin

Developing a reliable method to detect Na2S2O4 in real time is of great importance for the in-depth study of its toxicity to humans and to allow it to be safely handled.

2021 ◽  
pp. 019459982110492
Author(s):  
Allan M. Henslee ◽  
Christopher R. Kaufmann ◽  
Matt D. Andrick ◽  
Parker T. Reineke ◽  
Viral D. Tejani ◽  
...  

Objective Electrocochleography (ECochG) is increasingly being used during cochlear implant (CI) surgery to detect and mitigate insertion-related intracochlear trauma, where a drop in ECochG signal has been shown to correlate with a decline in hearing outcomes. In this study, an ECochG-guided robotics-assisted CI insertion system was developed and characterized that provides controlled and consistent electrode array insertions while monitoring and adapting to real-time ECochG signals. Study Design Experimental research. Setting A research laboratory and animal testing facility. Methods A proof-of-concept benchtop study evaluated the ability of the system to detect simulated ECochG signal changes and robotically adapt the insertion. Additionally, the ECochG-guided insertion system was evaluated in a pilot in vivo sheep study to characterize the signal-to-noise ratio and amplitude of ECochG recordings during robotics-assisted insertions. The system comprises an electrode array insertion drive unit, an extracochlear recording electrode module, and a control console that interfaces with both components and the surgeon. Results The system exhibited a microvolt signal resolution and a response time <100 milliseconds after signal change detection, indicating that the system can detect changes and respond faster than a human. Additionally, animal results demonstrated that the system was capable of recording ECochG signals with a high signal-to-noise ratio and sufficient amplitude. Conclusion An ECochG-guided robotics-assisted CI insertion system can detect real-time drops in ECochG signals during electrode array insertions and immediately alter the insertion motion. The system may provide a surgeon the means to monitor and reduce CI insertion–related trauma beyond manual insertion techniques for improved CI hearing outcomes.


2017 ◽  
Vol 96 (5) ◽  
pp. 817-827 ◽  
Author(s):  
Akimasa Ishida ◽  
Atsushi Imamura ◽  
Yoshitomo Ueda ◽  
Takeshi Shimizu ◽  
Ryosuke Marumoto ◽  
...  

Nanophotonics ◽  
2020 ◽  
Vol 9 (10) ◽  
pp. 3443-3450 ◽  
Author(s):  
Wei-Nan Liu ◽  
Rui Chen ◽  
Wei-Yi Shi ◽  
Ke-Bo Zeng ◽  
Fu-Li Zhao ◽  
...  

AbstractSelective transmission or filtering always responds to either frequency or incident angle, so as hardly to maximize signal-to-noise ratio in communication, detection and sensing. Here, we propose compact meta-filters of narrow-frequency sharp-angular transmission peak along with broad omnidirectional reflection sidebands, in all-dielectric cascaded subwavelength meta-gratings. The inherent collective resonance of waveguide-array modes and thin film approximation of meta-grating are employed as the design strategy. A unity transmission peak, locating at the incident angle of 44.4° and the center wavelength of 1550 nm, is demonstrated in a silicon meta-filter consisting of two-layer silicon rectangular meta-grating. These findings provide possibilities in cascaded meta-gratings spectroscopic design and alternative utilities for high signal-to-noise ratio applications in focus-free spatial filtering and anti-noise systems in telecommunications.


2016 ◽  
Vol 7 (2) ◽  
pp. 381 ◽  
Author(s):  
Lukas B. Gromann ◽  
Dirk Bequé ◽  
Kai Scherer ◽  
Konstantin Willer ◽  
Lorenz Birnbacher ◽  
...  

2014 ◽  
Vol 556-562 ◽  
pp. 6328-6331
Author(s):  
Su Zhen Shi ◽  
Yi Chen Zhao ◽  
Li Biao Yang ◽  
Yao Tang ◽  
Juan Li

The LIFT technology has applied in process of denoising to ensure the imaging precision of minor faults and structure in 3D coalfield seismic processing. The paper focused on the denoising process in two study areas where the LIFT technology is used. The separation of signal and noise is done firstly. Then denoising would be done in the noise data. The Data of weak effective signal that is from the noise data could be blended with the original effective signal to reconstruct the denoising data, so the result which has high signal-to-noise ratio and preserved amplitude is acquired. Thus the fact shows that LIFT is an effective denoising method for 3D seismic in coalfield and could be used widely in other work area.


2006 ◽  
Author(s):  
Stanley Wissmar ◽  
Linda Höglund ◽  
Jan Andersson ◽  
Christian Vieider ◽  
Susan Savage ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document