Design of a microfluidic device for the measurement of the elastic modulus of deformable particles

Soft Matter ◽  
2019 ◽  
Vol 15 (5) ◽  
pp. 880-889 ◽  
Author(s):  
Massimiliano M. Villone ◽  
Janine K. Nunes ◽  
Yankai Li ◽  
Howard A. Stone ◽  
Pier Luca Maffettone
Keyword(s):  
Elastic Modulus ◽  
Interfacial Tension ◽  
Continuous Flow ◽  
Liquid Droplet ◽  
Flow Process ◽  
Deformable Particles ◽  
Soft Particles ◽  
Continuous Flow Process ◽  
Microfluidic Technique

A microfluidic technique recently proposed in the literature to measure the interfacial tension between a liquid droplet and an immiscible suspending liquid [Hudson et al., Appl. Phys. Lett., 2005, 87, 081905], [Cabral and Hudson, Lab Chip, 2006, 6, 427] is suitably adapted to the characterization of the elastic modulus of soft particles in a continuous-flow process.

Upgrading from batch to continuous flow process for the pyrolysis of sugarcane bagasse: Structural characterization of the biochars produced

2021 ◽  
Vol 285 ◽  
pp. 112145
Author(s):  
Paulo Apolinário da Silva Veiga ◽  
Matheus Henrique Cerqueira ◽  
Mayara Gabriela Gonçalves ◽  
Tassya Thaiza da Silva Matos ◽  
Glaucia Pantano ◽  
...  
Keyword(s):  
Sugarcane Bagasse ◽  
Structural Characterization ◽  
Continuous Flow ◽  
Flow Process ◽  
Continuous Flow Process

scholarly journals Design Of An Optofluidic Device For The Measurement Of The Elastic Modulus Of Deformable Particles

2019 ◽  
Vol 215 ◽  
pp. 14003
Author(s):  
Massimiliano M. Villone ◽  
Janine K. Nunes ◽  
Howard A. Stone ◽  
Pier Luca Maffettone
Keyword(s):  
Mechanical Properties ◽  
Elastic Modulus ◽  
Real Time ◽  
Cross Section ◽  
Microfluidic Channel ◽  
Immiscible Liquids ◽  
Non Invasive ◽  
Deformable Particles ◽  
Soft Particles

Suspensions carrying deformable inclusions are ubiquitous in nature and applications. Hence, high-throughput characterization of the mechanical properties of soft particles is of great interest. Recently, a non-invasive optofluidic technique has been developed for the measurement of the interfacial tension between two immiscible liquids [8]. We have adapted such technique to the case of soft solid beads, thus designing a non-invasive optofluidic device for the measurement of the mechanical properties of deformable particles from real-time optical imaging of their deformation. The device consists of a cylindrical microfluidic channel with a cross-section reduction in which we make initially spherical soft beads flow suspended in a Newtonian carrier. By imaging the deformation of a particle in real time while it goes through the constriction, it is possible to get a measure of its elastic modulus through a theoretically derived-correlation. We provide both experimental and numerical validation of our device.

A Continuous Flow Process for LSN647712 via Double Organometallic Additions to Dimethylcarbamyl Chloride

2021 ◽  
Author(s):  
Hui Li ◽  
Jillian W. Sheeran ◽  
David Kouvchinov ◽  
Andrew M. Clausen ◽  
Ian T. Crouch ◽  
...  
Keyword(s):  
Continuous Flow ◽  
Flow Process ◽  
Continuous Flow Process

Assessing inter- and intramolecular continuous-flow strategies towards methylphenidate (Ritalin) hydrochloride

2017 ◽  
Vol 2 (2) ◽  
pp. 149-158 ◽  
Author(s):  
Romaric Gérardy ◽  
Marc Winter ◽  
Alessandra Vizza ◽  
Jean-Christophe M. Monbaliu
Keyword(s):  
Continuous Flow ◽  
Flow Process ◽  
Continuous Flow Process

Development of a scalable continuous-flow process towards enriched threo-methylphenidate (Ritalin) hydrochloride.

Continuous-Flow Process for Selective Mononitration of 1-Methyl-4-(methylsulfonyl)benzene

2016 ◽  
Vol 20 (2) ◽  
pp. 199-203 ◽  
Author(s):  
Zhiqun Yu ◽  
Pengcheng Zhou ◽  
Jiming Liu ◽  
Wenzuo Wang ◽  
Chuanming Yu ◽  
...  
Keyword(s):  
Continuous Flow ◽  
Flow Process ◽  
Continuous Flow Process

Continuous Flow Process for Reductive Deoxygenation of ω-Chloroketone in the Synthesis of Vilazodone

2018 ◽  
Vol 22 (8) ◽  
pp. 1022-1028 ◽  
Author(s):  
Avedis Karadeolian ◽  
Dineshkumar Patel ◽  
Prabhudas Bodhuri ◽  
Gamini Weeratunga ◽  
Boris Gorin
Keyword(s):  
Continuous Flow ◽  
Flow Process ◽  
Continuous Flow Process

Continuous flow synthesis of amine oxides by oxidation of tertiary amines

2019 ◽  
Vol 4 (7) ◽  
pp. 1270-1276
Author(s):  
Tobias Baumeister ◽  
Stefan Zikeli ◽  
Hannes Kitzler ◽  
Paul Aigner ◽  
Piotr P. Wieczorek ◽  
...  
Keyword(s):  
Hydrogen Peroxide ◽  
Continuous Flow ◽  
Tertiary Amines ◽  
Flow Process ◽  
Flow Synthesis ◽  
Amine Oxides ◽  
Continuous Flow Process

An efficient, safe and scalable continuous flow process for the synthesis of amine oxides with hydrogen peroxide is described.

Development of a Continuous Flow Process for a Matteson Reaction: From Lab Scale to Full-Scale Production of a Pharmaceutical Intermediate

2019 ◽  
Vol 23 (5) ◽  
pp. 1069-1077 ◽  
Author(s):  
Clemens Stueckler ◽  
Peter Hermsen ◽  
Bas Ritzen ◽  
Maria Vasiloiu ◽  
Peter Poechlauer ◽  
...  
Keyword(s):  
Continuous Flow ◽  
Full Scale ◽  
Scale Production ◽  
Flow Process ◽  
Continuous Flow Process

Effective production of the biodiesel additive STBE by a continuous flow process

2011 ◽  
Vol 102 (19) ◽  
pp. 9304-9307 ◽  
Author(s):  
Jean-Christophe M. Monbaliu ◽  
Marc Winter ◽  
Bérengère Chevalier ◽  
Frank Schmidt ◽  
Yi Jiang ◽  
...  
Keyword(s):  
Continuous Flow ◽  
Flow Process ◽  
Continuous Flow Process
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