scholarly journals Highly luminescent, biocompatible ytterbium(iii) complexes as near-infrared fluorophores for living cell imaging

2018 ◽  
Vol 9 (15) ◽  
pp. 3742-3753 ◽  
Author(s):  
Yingying Ning ◽  
Juan Tang ◽  
Yi-Wei Liu ◽  
Jing Jing ◽  
Yuansheng Sun ◽  
...  
Keyword(s):  
Living Cell ◽  
Near Infrared ◽  
Cell Imaging ◽  
Aqueous Media ◽  
Synthetic Methods ◽  
Quantum Yields ◽  
Fluorescence Lifetime Imaging ◽  
Time Resolved ◽  
Lifetime Imaging ◽  
Living Cell Imaging

We report three synthetic methods to prepare biocompatible Yb3+complexes, which displayed high NIR luminescence with quantum yields up to 13% in aqueous media. This renders β-fluorinated Yb3+porphyrinoids a new class of NIR probes for living cell imaging including time-resolved fluorescence lifetime imaging.

scholarly journals Biocompatible Ir(III) Complexes as Oxygen Sensors for Phosphorescence Lifetime Imaging

Molecules ◽  
2021 ◽  
Vol 26 (10) ◽  
pp. 2898
Author(s):  
Ilya S. Kritchenkov ◽  
Anastasia I. Solomatina ◽  
Daria O. Kozina ◽  
Vitaly V. Porsev ◽  
Victor V. Sokolov ◽  
...  
Keyword(s):  
Near Infrared ◽  
Biological Systems ◽  
Aqueous Media ◽  
Oxygen Sensors ◽  
Quantum Yields ◽  
Complete Agreement ◽  
Phosphorescence Lifetime ◽  
Lifetime Imaging ◽  
Nir Emission ◽  
Phosphorescence Lifetime Imaging

Synthesis of biocompatible near infrared phosphorescent complexes and their application in bioimaging as triplet oxygen sensors in live systems are still challenging areas of organometallic chemistry. We have designed and synthetized four novel iridium [Ir(N^C)2(N^N)]+ complexes (N^C–benzothienyl-phenanthridine based cyclometalated ligand; N^N–pyridin-phenanthroimidazol diimine chelate), decorated with oligo(ethylene glycol) groups to impart these emitters’ solubility in aqueous media, biocompatibility, and to shield them from interaction with bio-environment. These substances were fully characterized using NMR spectroscopy and ESI mass-spectrometry. The complexes exhibited excitation close to the biological “window of transparency”, NIR emission at 730 nm, and quantum yields up to 12% in water. The compounds with higher degree of the chromophore shielding possess low toxicity, bleaching stability, absence of sensitivity to variations of pH, serum, and complex concentrations. The properties of these probes as oxygen sensors for biological systems have been studied by using phosphorescence lifetime imaging experiments in different cell cultures. The results showed essential lifetime response onto variations in oxygen concentration (2.0–2.3 μs under normoxia and 2.8–3.0 μs under hypoxia conditions) in complete agreement with the calibration curves obtained “in cuvette”. The data obtained indicate that these emitters can be used as semi-quantitative oxygen sensors in biological systems.

A near-infrared “on–off” fluorescent and colourimetric cyanide chemodosimeter based on phenothiazine with applications in living cell imaging

RSC Advances ◽  
2014 ◽  
Vol 4 (104) ◽  
pp. 59809-59816 ◽  
Author(s):  
Qi Zou ◽  
Xin Li ◽  
Qunjie Xu ◽  
Hans Ågren ◽  
Wandong Zhao ◽  
...  
Keyword(s):  
Living Cell ◽  
Near Infrared ◽  
Cell Imaging ◽  
Living Cell Imaging

scholarly journals Tetraphenylethylene- and fluorene-functionalized near-infrared aza-BODIPY dyes for living cell imaging

RSC Advances ◽  
2017 ◽  
Vol 7 (88) ◽  
pp. 55839-55845 ◽  
Author(s):  
Li Zhu ◽  
Wensheng Xie ◽  
Lingyun Zhao ◽  
Yongjie Zhang ◽  
Zhijian Chen
Keyword(s):  
Living Cell ◽  
Near Infrared ◽  
Cell Imaging ◽  
Application Potential ◽  
Living Cell Imaging

The new NIR absorbing aza-BODIPY dyes bearing tetraphenylethylene and fluorinyl substituents were synthesized and characterized. The application potential of these new dyes in living cell imaging was demonstrated.

A near-infrared fluorescent probe for the ratiometric detection and living cell imaging of β-galactosidase

2019 ◽  
Vol 411 (30) ◽  
pp. 7957-7966 ◽  
Author(s):  
Xueyan Zhang ◽  
Xiangzhu Chen ◽  
Yuanyuan Zhang ◽  
Kaizheng Liu ◽  
Hongjing Shen ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Living Cell ◽  
Near Infrared ◽  
Cell Imaging ◽  
Ratiometric Detection ◽  
Living Cell Imaging

A Near‐Infrared Fluorescence Chemosensor Based on Isothiocyanate‐Aza‐BODIPY for Cyanide Detection at the Parts per Billion Level: Applications in Buffer Media and Living Cell Imaging

ChemPlusChem ◽  
2019 ◽  
Vol 84 (3) ◽  
pp. 252-259 ◽  
Author(s):  
Pornthip Piyanuch ◽  
Jitnapa Sirirak ◽  
Anyanee Kamkaew ◽  
Oratai Weeranantanapan ◽  
Vinich Promarak ◽  
...  
Keyword(s):  
Living Cell ◽  
Near Infrared ◽  
Cell Imaging ◽  
Near Infrared Fluorescence ◽  
Living Cell Imaging

Turn-On Ratiometric Fluorescent Probe for Selective Discrimination of Cr3+from Fe3+in Aqueous Media for Living Cell Imaging

2015 ◽  
Vol 21 (46) ◽  
pp. 16349-16353 ◽  
Author(s):  
Lubna Rasheed ◽  
Muhammad Yousuf ◽  
Il Seung Youn ◽  
Taeseung Yoon ◽  
Kwang-Youn Kim ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Living Cell ◽  
Cell Imaging ◽  
Aqueous Media ◽  
Turn On ◽  
Living Cell Imaging ◽  
Ratiometric Fluorescent Probe

Pyrrole-coupled salicylimine-based fluorescence “turn on” probe for highly selective recognition of Zn2+ions in mixed aqueous media: Application in living cell imaging

2015 ◽  
Vol 28 (6) ◽  
pp. 369-375 ◽  
Author(s):  
Jitendra Bhosale ◽  
Umesh Fegade ◽  
Banashree Bondhopadhyay ◽  
Simanpreet Kaur ◽  
Narinder Singh ◽  
...  
Keyword(s):  
Living Cell ◽  
Cell Imaging ◽  
Aqueous Media ◽  
Selective Recognition ◽  
Turn On ◽  
Fluorescence Turn On ◽  
Living Cell Imaging

A reversible turn-on colorimetric and fluorescent sensor for Al3+ in fully aqueous media and its living cell imaging

2016 ◽  
Vol 221 ◽  
pp. 206-213 ◽  
Author(s):  
Li Yuan Qin ◽  
Ling Jie Hou ◽  
Jia Feng ◽  
Jian Bin Chao ◽  
Yu Wang ◽  
...  
Keyword(s):  
Living Cell ◽  
Cell Imaging ◽  
Fluorescent Sensor ◽  
Aqueous Media ◽  
Turn On ◽  
Living Cell Imaging

Bis-biphenylacrylonitrile bridged with crown ether chain: a novel fluorescence sensor for Fe3+ in aqueous media

2020 ◽  
Vol 44 (27) ◽  
pp. 11746-11751
Author(s):  
Haifeng Ma ◽  
Rongqin Wu ◽  
Jie Xiong ◽  
Hongyu Guo ◽  
Fafu Yang
Keyword(s):  
Crown Ether ◽  
Living Cell ◽  
Cell Imaging ◽  
Aqueous Media ◽  
Fluorescence Sensor ◽  
Living Cell Imaging

A novel fluorescence sensor for Fe3+ in aqueous media was developed and applied for living-cell imaging.

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