scholarly journals Indirect study of the effect of α-tocopherol and acetylsalicylic acid on the mineral composition of bone tissue in the offspring of female rats treated with 2,3,7,8-tetrachlorodibenzo-p-dioxin: long-term observations

RSC Advances ◽  
2019 ◽  
Vol 9 (14) ◽  
pp. 8016-8024 ◽  
Author(s):  
Maciej Dobrzynski ◽  
Piotr Kuropka ◽  
Malgorzata Tarnowska ◽  
Krzysztof Dudek ◽  
Marzena Styczynska ◽  
...  
Keyword(s):  
Acetylsalicylic Acid ◽  
Bone Tissue ◽  
Mineral Composition ◽  
Female Rats ◽  
Tetrachlorodibenzo P Dioxin

This paper discusses problems related to the influence of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on the mineral composition of the calvaria in the offspring of female rats.

scholarly journals Modulating effect of selected pharmaceuticals on bone in female rats exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)

RSC Advances ◽  
2018 ◽  
Vol 8 (48) ◽  
pp. 27537-27545 ◽  
Author(s):  
Maciej Dobrzynski ◽  
Celina Pezowicz ◽  
Magdalena Tomanik ◽  
Piotr Kuropka ◽  
Krzysztof Dudek ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Bone Tissue ◽  
Female Rats ◽  
Tetrachlorodibenzo P Dioxin

This paper discusses the problems regarding the influence of TCDD on the mechanical properties and structure of the bone tissue in female rats treated with the dioxin.

Mineral composition and gemological characteristics of the fossil marine reptiles of the Ulyanovsk region

2018 ◽  
pp. 12-16 ◽  
Author(s):  
D. A. Petrochenkov
Keyword(s):  
Chemical Composition ◽  
Bone Tissue ◽  
Mineral Composition ◽  
Bone Structure ◽  
Upper Jurassic ◽  
Marine Reptiles ◽  
Ulyanovsk Region ◽  
Impurity Elements ◽  
Wide Assortment

Fossils of marine reptiles are a new jewelry and ornamental material and collected in the Ulyanovsk region from the Upper Jurassic deposits. They consist of (wt. %): calcite — 52, apatite — 24 and pyrite — 23, and also gypsum presents. The contents of radioactive and carcinogenic elements are close to background. The original bone structure of reptiles is preserved. Apatite replaces the bone tissue of marine reptiles, forming a cellular framework. According to the chemical composition, apatite refers to fluorohydroxyapatite with an increased Sr content. The size of the crystals is finely-dispersed. Calcite and pyrite fill the central parts of the cells. Calcite crystals of isometric and elongated shape, 0,01—0,05 mm in size, form blocks up to 0,3 mm during intergrowth. Calcite fills thin, discontinuous veins along the contour of cells with a width of up to 0,03 mm. In calcite, among the impurity elements, there are (wt. %, on the average): Mg — 0,30, Mn — 0,39 and Fe — 0,96. Pyrite forms a dispersed impregnation in calcite and apatite, content of impurities is, wt. %: Ni — up to 0,96 and Cu — up to 0,24. On technological and decorative characteristics of fossils of sea reptiles of Ulyanovsk region are qualitative jewelry and ornamental materials of biomineral group, allowing to make a wide assortment of jewelry and souvenir products.

Long-Term Exercise Training Selectively Alters Serum Cytokines Involved in Fever

2009 ◽  
Vol 10 (4) ◽  
pp. 374-380 ◽  
Author(s):  
Pamela Johnson Rowsey ◽  
Bonnie L. Metzger ◽  
John Carlson ◽  
Christopher J. Gordon
Keyword(s):  
Exercise Training ◽  
Core Temperature ◽  
Binding Capacity ◽  
Serum Zinc ◽  
Female Rats ◽  
Chronic Exercise ◽  
Serum Cytokines ◽  
Tnf Α ◽  
Running Wheels

Long-term exercise training selectively alters serum cytokines involved in fever. Chronic exercise training has a number of effects on the immune system that may mimic the physiological response to fever. Female rats that voluntarily exercise on running wheels develop an elevated daytime core temperature after several weeks of training. It remains to be seen whether the elevation in daytime temperature involves inflammatory patterns characteristic of an infectious fever. We assessed whether chronic exercise training in the rat would alter levels of cytokines involved in fever. Female Sprague Dawley rats at 45 days of age weighing 90—110 g were divided into two groups (exercise and sedentary) and housed at an ambient temperature of 22°C. Interleukin-1 beta (IL-1β), interleukin-6 (IL-6), interleukin-10 (IL-10), tumor necrosis factor alpha (TNF-α), iron, and zinc levels were analyzed. Rats underwent 8 weeks of exercise on running wheels. Exercise led to altered levels of some key cytokines that are involved in fever. Exercise animals had significantly higher IL-1β levels and lower IL-10 levels compared to sedentary animals. Although IL-6 levels were slightly lower in the exercise animals, these levels were not significantly affected by training. TNF-α activity was similar in the two groups. Training also led to a slight increase in serum zinc and decrease in serum unsaturated iron binding capacity (UIBC). The data suggest that chronic exercise training evokes immune responses that mimic some, but not all, aspects of fever. This may explain why exercise leads to elevated daytime core temperature.

Influence of long-term manure application on mineral composition of irrigated barley silage

2015 ◽  
Vol 95 (4) ◽  
pp. 759-770 ◽  
Author(s):  
J. J. Miller ◽  
B. W. Beasley ◽  
C. F. Drury ◽  
F. J. Larney ◽  
X. Hao
Keyword(s):  
Mineral Composition ◽  
Application Rate ◽  
Land Application ◽  
Wood Chips ◽  
Fertilizer Treatment ◽  
Manure Application ◽  
Feed Quality ◽  
Barley Silage

Miller, J. J., Beasley, B. W., Drury, C. F., Larney, F. and Hao, X. 2015. Influence of long-term manure application on mineral composition of irrigated barley silage. Can. J. Plant Sci. 95: 759–770. The long-term effect of land application of manure type (composted vs. stockpiled manure), bedding type (wood-chips vs. straw), and application rate on feed quality of barley silage as feed for beef cattle is unknown. We measured selected minerals [P, Ca, Ca:P ratio, Mg, K, K:(Ca+Mg) ratio, Na, Fe, Mn, Zn, Cu] of irrigated barley silage (Hordeum vulgare L.) on a clay loam soil after 4 (2002), 7 (2005) and 11 (2009) years of annual applications of composted (CM) or stockpiled (SM) feedlot manure with wood-chips (WD) or straw (ST) bedding at three application rates (13, 39, 77Mg ha−1 dry wt.). The treatments also included an unamended control and inorganic fertilizer treatment. Manure type generally had inconsistent or no significant (P≤0.05) effect on the concentrations of these minerals in barley silage. Most crop minerals were generally greater under ST than WD. The findings for P, K, Na, and K:(Ca+Mg) ratio generally supported our hypothesis of greater crop concentrations with greater application rate, but Ca and Mg decreased at higher rates. Overall, our findings suggest that bedding and application rate have more potential than manure type for managing the feed quality of barley silage.

Cortical neuroinflammation contributes to long-term cognitive dysfunctions following adolescent delta-9-tetrahydrocannabinol treatment in female rats

2015 ◽  
Vol 25 (12) ◽  
pp. 2404-2415 ◽  
Author(s):  
Erica Zamberletti ◽  
Marina Gabaglio ◽  
Pamela Prini ◽  
Tiziana Rubino ◽  
Daniela Parolaro
Keyword(s):  
Female Rats ◽  
Cognitive Dysfunctions

scholarly journals Effect of long-term high-fat diet intake on peripheral insulin sensibility, blood pressure, and renal function in female rats

2016 ◽  
Vol 60 (1) ◽  
pp. 28536 ◽  
Author(s):  
Noemi A. V. Roza ◽  
Luiz F. Possignolo ◽  
Adrianne C. Palanch ◽  
José A. R. Gontijo
Keyword(s):  
Blood Pressure ◽  
Renal Function ◽  
High Fat Diet ◽  
Female Rats ◽  
High Fat ◽  
Diet Intake

Effects of long-term administration of high doses of medroxyprogesterone acetate on hormone receptors and target organs in the female rat

1984 ◽  
Vol 103 (3) ◽  
pp. 287-293 ◽  
Author(s):  
F. Di Carlo ◽  
S. Racca ◽  
G. Conti ◽  
E. Gallo ◽  
G. Muccioli ◽  
...  
Keyword(s):  
Pituitary Gland ◽  
Medroxyprogesterone Acetate ◽  
Prolactin Receptor ◽  
Female Rats ◽  
Serum Prolactin ◽  
Target Organs ◽  
Term Administration ◽  
Pituitary Glands ◽  
High Doses

ABSTRACT The changes in oestrogen, progesterone and prolactin receptor levels in target organs, and the macroscopic and microscopic modifications of uterus, ovary, adrenal and pituitary gland induced by long-term administration of high doses of medroxyprogesterone acetate (MPA) were investigated in female rats. Medroxyprogesterone acetate was injected i.m. for 30 days at daily doses of 7·5, 15 and 75 mg/kg. Oestrogen and/or progesterone-binding capacities were remarkably reduced at all doses of MPA used both in the uterus and pituitary gland. Furthermore, MPA caused a very evident reduction in the weight of pituitary glands, ovaries, adrenals and uterus. In all MPA-treated rats corpora lutea were absent from the ovaries, whereas the adrenals showed a significant reduction in the thickness of the cortex. In accordance with this, there was no evidence of ACTH-producing cells in the pituitary glands. Prolactin-producing cells were also absent, while GH-producing cells were present. Serum prolactin levels were significantly reduced at all doses of MPA used. A dramatic reduction of prolactin receptor concentrations was observed in the liver and the ovaries of MPA-treated rats. The results suggest that MPA acts as an antioestrogenic drug both by reducing the number of oestrogen receptors in target tissues and by changing the structure (and perhaps the function) of those organs (pituitary glands, ovaries and adrenals) which are, directly or indirectly, a source of oestrogens. The decreased synthesis of prolactin and the reduction of the number of prolactin receptors (which, on the contrary, are both increased by oestrogens) might be considered as additional antioestrogenic effects of MPA. J. Endocr. (1984) 103, 287–293

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