scholarly journals A simple liquid chromatography-tandem mass spectrometry method to accurately determine the novel third-generation EGFR-TKI naquotinib with its applicability to metabolic stability assessment

RSC Advances ◽  
2019 ◽  
Vol 9 (9) ◽  
pp. 4862-4869 ◽  
Author(s):  
Haitham Alrabiah ◽  
Adnan A. Kadi ◽  
Mohamed W. Attwa ◽  
Ali S. Abdelhameed
Keyword(s):  
Mass Spectrometry ◽  
Simple Liquid ◽  
Tandem Mass ◽  
Third Generation ◽  
The Novel ◽  
Stability Assessment ◽  
Spectrometry Method ◽  
Chromatography Tandem Mass Spectrometry ◽  
Liquid Chromatography Tandem Mass ◽  
Egfr Tki

The first established LC-MS/MS method for NQT analysis. NQT was shown to be moderately excreted from the human body.

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