scholarly journals Sulfur(vi) fluoride exchange as a key reaction for synthesizing biaryl sulfate core derivatives as potent hepatitis C virus NS5A inhibitors and their structure–activity relationship studies

RSC Advances ◽  
2018 ◽  
Vol 8 (55) ◽  
pp. 31803-31821 ◽  
Author(s):  
Youngsu You ◽  
Hee Sun Kim ◽  
Jung Woo Park ◽  
Gyochang Keum ◽  
Sung Key Jang ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Design And Synthesis ◽  
Structure Activity

SuFEx chemistry was utilized for the design and synthesis of potent HCV NS5A inhibitors featuring a biaryl sulfate core.

Large-scale structure-activity relationship study of hepatitis C virus NS5B polymerase inhibition using SMILES-based descriptors

2015 ◽  
Vol 19 (4) ◽  
pp. 955-964 ◽  
Author(s):  
Apilak Worachartcheewan ◽  
Virapong Prachayasittikul ◽  
Alla P. Toropova ◽  
Andrey A. Toropov ◽  
Chanin Nantasenamat
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Large Scale ◽  
Large Scale Structure ◽  
Structure Activity Relationship ◽  
Scale Structure ◽  
Activity Relationship ◽  
Structure Activity ◽  
Relationship Study ◽  
Ns5b Polymerase

Discovery and Structure−Activity Relationship of P1−P3Ketoamide Derived Macrocyclic Inhibitors of Hepatitis C Virus NS3 Protease

2009 ◽  
Vol 52 (2) ◽  
pp. 336-346 ◽  
Author(s):  
Srikanth Venkatraman ◽  
Francisco Velazquez ◽  
Wanli Wu ◽  
Melissa Blackman ◽  
Kevin X. Chen ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Structure Activity ◽  
Relationship Of ◽  
Ns3 Protease

Peptide-Based Inhibitors of the Hepatitis C Virus NS3 Protease:  Structure−Activity Relationship at theC-Terminal Position

2004 ◽  
Vol 47 (10) ◽  
pp. 2511-2522 ◽  
Author(s):  
Jean Rancourt ◽  
Dale R. Cameron ◽  
Vida Gorys ◽  
Daniel Lamarre ◽  
Martin Poirier ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Terminal Position ◽  
Structure Activity ◽  
Ns3 Protease

Structure−Activity Relationship of New Anti-Hepatitis C Virus Agents: Heterobicycle−Coumarin Conjugates

2009 ◽  
Vol 52 (5) ◽  
pp. 1486-1490 ◽  
Author(s):  
Johan Neyts ◽  
Erik De Clercq ◽  
Raghunath Singha ◽  
Yung Hsiung Chang ◽  
Asish R. Das ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Structure Activity ◽  
Relationship Of
Sign in / Sign up

Export Citation Format

Share Document