scholarly journals Lactobionic acid-functionalized polyethersulfone hollow fiber membranes promote HepG2 attachment and function

RSC Advances ◽  
2018 ◽  
Vol 8 (51) ◽  
pp. 29078-29088 ◽  
Author(s):  
Surendra Kumar Verma ◽  
Akshay Modi ◽  
Ashwin Dravid ◽  
Jayesh Bellare

Surface modification of polyethersulfone hollow fibers, which are important in bio-artificial liver, is increasingly used to improve biocompatibility and promote the adhesion and proliferation of hepatocytes resulting in improved cell functionality.

Author(s):  
K.C. Khulbe ◽  
C. Feng ◽  
T. Matsuura ◽  
M. Khayet

In this article an attempt is made to review critically the papers published recently on polymeric hollow fibers and hollow fiber membranes. Hollow fiber membranes emerged in early nineteen sixties at almost the same time as the announcement of the cellulose acetate reverse osmosis membrane for seawater desalination by Loeb and Sourirajan. Since then, the hollow fiber technology has progressed along with the industrial membrane separation processes. Today, hollow fiber membranes are being used in every sector of the manufacturing industry, including gas and vapor separation, seawater desalination and waste water treatment. The fabrication of a hollow fiber membrane with a desirable pore–size distribution and performance is not an easy task. There are many factors controlling fiber morphology during the phase inversion process and, at present, we are not able to say that we fully understand the phenomena involved in the fabrication of hollow fibers. Nevertheless, there has been a large amount of knowledge accumulated during the past fifteen years, which has been supported by an equally large amount of efforts by many researchers. This paper attempts to summarize those works. The authors could however look into only those reports which have appeared in scientific journals and few patents, and they are fully aware that there must be much more information that has not surfaced to the journal publication. It is also the authors’ intention to show the future direction including the research topics that have been studied only little or not at all.


RSC Advances ◽  
2018 ◽  
Vol 8 (1) ◽  
pp. 102-110 ◽  
Author(s):  
Yan-wei You ◽  
Chang-fa Xiao ◽  
Qing-lin Huang ◽  
Yan Huang ◽  
Chun Wang ◽  
...  

FEP/PPy composite hollow fiber membranes were prepared by PPy layer polymerization on the outer surface of FEP hollow fiber membranesviaa chemical vapor deposition method.


2016 ◽  
Vol 78 (12) ◽  
Author(s):  
Mohd Izzat Iqbal Mohd Zahar ◽  
Mohd Hafiz Dzarfan Othman ◽  
Mukhlis A Rahman ◽  
Juhana Jaafar ◽  
Siti Khadijah Hubadillah

A systematic study of the air gap effects on morphology and mechanical strength of Nickel Oxide (NiO) hollow fiber membranes has been carried out. The hollow fibers were prepared using the dry-jet wet spinning process using a dope solution containing NiO/N-methyl-2-pyrrolidone (NMP)/Arlacel/Poly(ethylene sulphide) with a weight ratio of 70/22.9/0.1/7. Tap water was used as internal and external coagulants. The cross-sectional structure of precursors hollow fiber membrane was studied by scanning electron microscopy (SEM). The results showed that both inner and outer finger-like voids of the hollow membrane were determined by the air gap distance. Experimental results indicated that an increase in air gap distance, from 100 mm to 200 mm, gave a hollow fiber with a lower mechanical strength and higher percentages of cross section surface area covered by finger-like voids structures. This study also revealed that the air gap introduced an elongation stress because of gravity on the internal or external surfaces of the NiO hollow fibers. A more effective hollow fiber membrane which is in asymmetric structure instead of symmetric structure can be produced by using air gap higher than 200 mm. 


2017 ◽  
Vol 114 ◽  
pp. 110-117 ◽  
Author(s):  
Haiming Song ◽  
Hongwei Yu ◽  
Lijing Zhu ◽  
Lixin Xue ◽  
Dichao Wu ◽  
...  

Author(s):  
Hua Liu ◽  
Jinyun Liu ◽  
Zhou Hong ◽  
Shengxian Wang ◽  
Xuechao Gao ◽  
...  

Abstract Porous mullite hollow fiber membranes were prepared with a combined phase-inversion and sintering method, using three sintering additives including yttrium stabilized zirconia (YSZ), small mullite particles (SMP), and titanium oxide (TiO2) to promote the particle sintering. The results indicated that all the three additives could improve the sintering performance of mullite hollow fiber membranes due to the decrease in activation energy of mullite grains. Both YSZ and TiO2 could react with mullite grains to generate composite oxides (e.g., ZrSiO4 and Al2TiO5) during sintering, following a reaction-sintering mechanism. Interestingly, the newly generated ZrSiO4 was instable and further decomposed into monoclinic ZrO2 and SiO2 in the sintering process. The decomposition could avoid excessive embedment of composite oxides among mullite grains which have negative impact on mechanical strength of mullite hollow fibers. Overall, the doping of YSZ provided a better promotion effect on the sintering of mullite hollow fiber membranes, where the microstructural and mechanical properties are insensitive to the doping content and sintering temperatures, so it could be used as the candidate for the large-scale preparation of mullite hollow fibers.


1994 ◽  
Vol 51 (1) ◽  
pp. 193-199 ◽  
Author(s):  
S. Mok ◽  
D. J. Worsfold ◽  
A. Fouda ◽  
T. Matsuura

2017 ◽  
Vol 6 (1) ◽  
Author(s):  
N. Bolong ◽  
A. F. Ismail ◽  
M. R. Salim

The effect of jet stretch on the morphology, pure water permeation and sodium chloride rejection of hollow fiber membranes is analyzed by varying the spinning take up speed. Polyethersulfone hollow fibers were spun using dry–wet spinning technique. The membrane formulation of PES/NMP/Water/PVPk10 is spun at constant extrusion rate of 3.0 cm3/ min. The fiber take up speed during spinning varied from 19.7 to 29.5 cms–1, revealed that the flux of hollow fiber membranes is minimal when the fiber take up speed is equivalent to the velocity of dope extrusion. At low jet stretch, the permeability of membranes is high with elevated ionic solutes rejection produced. The influence of elongation stress towards hollow fiber membranes morphology and its performance for water separation is also highlighted.


2018 ◽  
Vol 14 (3) ◽  
pp. 343-347 ◽  
Author(s):  
Sumarni Mansur ◽  
Mohd Hafiz Dzarfan Othman ◽  
Ahmad Fauzi Ismail ◽  
Muhammad Nidzhom Zainol Abidin ◽  
Noresah Said ◽  
...  

Asymmetric, porous ultrafiltration polysulfone (PSf) hollow fiber membranes were fabricated via the dry-wet phase inversion spinning technique specifically for haemodialysis membrane. The objective was to discover the suitable spinning condition for the fabrication of ultrafiltration hollow fiber membrane with desired sponge-like structure. During haemodialysis procedure, uremic toxins such as urea and creatinine range from size 10,000-55,000 Da needs to be excreted out from the blood. While, proteins such as albumin (66,000 Da) need to be retained. The physical structure or morphology of a fabricated membrane is a major concern in determining the efficiency of a dialysis membrane. Different type of membrane morphology will give a different result in term of its permeability and clearance efficiency. The phase inversion spinning technique is suitable in producing ultrafiltation (UF) membrane where the average pore size of the fabricated membrane is in the range of 0.001 – 0.1 µm. However, there is many factors need to be controlled and manipulated in the phase inversion technique. In this study, the effect of the PVP on membrane pore size and performances were analysed. The contact angle measurement was measured to determine the hydrophilicity of the fibers. The hydrophilic polymer is favorable to avoid fouling and increase its biocompatibility. Furthermore, the diameter of the hollow fibers was determined using a scanning electron microscope (SEM). The effects of different morphology of the hollow fibers on the performance of the membranes were evaluated by pure water flux and BSA rejection. Both techniques were tested using permeation flux system. Based on the results obtained, it is found that the finger-like macrovoids in PSf hollow fiber membranes were suppressed by adding 8% PVP (Mw of 360 kDa) into the spinning dope solution as the result of a drastic increase in dope viscosity. On top of that, fiber spun with 8% PVP show more porous structure which contribute to higher permeability of the membrane. The result of this study can benefit to the membrane field of research especially in membrane technology for haemodialysis application.


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