scholarly journals A simple two-photon turn-on fluorescent probe for the selective detection of cysteine based on a dual PeT/ICT mechanism

RSC Advances ◽  
2018 ◽  
Vol 8 (24) ◽  
pp. 13388-13392 ◽  
Author(s):  
Xiani Chen ◽  
Hang Xu ◽  
Shengnan Ma ◽  
Hongjuan Tong ◽  
Kaiyan Lou ◽  
...  

N-(6-acyl-2-naphthayl)-maleimide (1) is a simple two-photon fluorescent probe with selectivity for cysteine, based on a thiol-Michael-addition-transcyclization cascade and dual PeT/ICT quenching mechanism.

2014 ◽  
Vol 605 ◽  
pp. 19-22
Author(s):  
Hae Jo Kim

Two novel fluorescent chemodosimeters will be presented for the selective detection of cysteine over homocysteine and glutathione in aqueous solvent. First, a rhodamine-based fluorescent probe (1) will be reported. Masked with a para-hydroxybenzyl alcohol (HBA) unit, probe 1 initially showed a weak fluorescence but displayed a strong fluorescence through a series of reactions of Michael addition and intramolecular cyclization of cysteine, followed by deprotection of HBA. The caged probe (1) exhibited a selective and sensitive response toward cysteine over homocysteine and glutathione in HEPES buffer. Secondly, a fluorescein-based fluorescent probe will be discussed. A bromoacetyl functionalized fluorescein chemodosimeter (2) was utilized as a fluorescent probe for cysteine. The probe showed a selective and sensitive response to cysteine over homocysteine and glutathione in aqueous buffer through a rapid cyclization reaction. When cysteine was added, a fast fluorescence turn-on change of 2 was observed and applied to the in-vivo imaging of cysteine.


2019 ◽  
Vol 207 ◽  
pp. 613-619 ◽  
Author(s):  
Xiaofei Gu ◽  
Xiuxuan Zhang ◽  
Zhe Liu ◽  
Yu Cheng ◽  
Fulong Ma ◽  
...  

2017 ◽  
Vol 41 (4) ◽  
pp. 1653-1658 ◽  
Author(s):  
Yoon Jeong Jang ◽  
Sandip V. Mulay ◽  
Youngsam Kim ◽  
Perman Jorayev ◽  
David G. Churchill

A intramolecular cyclization reaction-based “turn-on” fluorescent probe (CoumNMe2) for selective detection of diethyl chlorophosphate (DCP) over close competitors diethyl cyanophosphonate (DECP), and diethyl methylphosphonate (DEMP) was developed.


Metallomics ◽  
2018 ◽  
Vol 10 (6) ◽  
pp. 794-801 ◽  
Author(s):  
Tasuku Hirayama ◽  
Satoki Kadota ◽  
Masato Niwa ◽  
Hideko Nagasawa

Development of a turn-on and selective fluorescent probe for mitochondrial labile Fe(ii).


RSC Advances ◽  
2019 ◽  
Vol 9 (62) ◽  
pp. 36011-36019 ◽  
Author(s):  
Meng-Xia Huang ◽  
Cai-Hua Lv ◽  
Qing-Da Huang ◽  
Jia-Ping Lai ◽  
Hui Sun

A novel, highly sensitive and fast responsive turn-on fluorescence probe ADMPA for Cd2+ was successfully developed based on 2,9-dimethyl-1,10-phenanthroline and o-aminophenol.


2015 ◽  
Vol 7 (6) ◽  
pp. 2386-2390 ◽  
Author(s):  
Tun Tang ◽  
Yimin Zhou ◽  
Yuqi Chen ◽  
Mengjun Li ◽  
Yan Feng ◽  
...  

A novel two-photon fluorescent “turn-on” probe could detect methylglyoxal levels in living cells conveniently.


2020 ◽  
Vol 180 ◽  
pp. 108435 ◽  
Author(s):  
Tingting Yang ◽  
Junyong Sun ◽  
Wu Yao ◽  
Feng Gao

The Analyst ◽  
2018 ◽  
Vol 143 (23) ◽  
pp. 5799-5804 ◽  
Author(s):  
Wan Sun ◽  
Jing-Xue Cui ◽  
Le-Le Ma ◽  
Zhong-Lin Lu ◽  
Bing Gong ◽  
...  

TP-2Bz, as a nucleus targeting “D–π–A” molecule, was developed as a two-photon turn-on fluorescent probe for the viscosity and GQ DNA detection in cell nuclei.


2017 ◽  
Vol 5 (1) ◽  
pp. 134-138 ◽  
Author(s):  
Jian-Yong Wang ◽  
Zhan-Rong Liu ◽  
Mingguang Ren ◽  
Xiuqi Kong ◽  
Weiying Lin

We developed a novel two-photon fluorescent probe for sensing Cys specifically. The two-photon fluorescent probe exhibited favorable properties and was successfully applied for imaging Cys in living cells and tissues.


2017 ◽  
Vol 9 (31) ◽  
pp. 4558-4565 ◽  
Author(s):  
Qiujuan Ma ◽  
Xian li ◽  
Jing Zhang ◽  
Xiaoyan Zhu ◽  
Liyi Zhou ◽  
...  

In this study, we report a novel two-photon fluorescent probe for monitoring hydrogen peroxide.


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