Synthesis of chiral seven-membered cyclic sulfonamides through palladium-catalyzed arylation of cyclic imines

2019 ◽  
Vol 6 (10) ◽  
pp. 1572-1576 ◽  
Author(s):  
Zi-Biao Zhao ◽  
Lei Shi ◽  
Fan-Jie Meng ◽  
Yaming Li ◽  
Yong-Gui Zhou

An enantioselective palladium-catalyzed addition of arylboronic acids to seven-membered cyclic N-sulfonyl aldimines and ketimines has been developed, giving the chiral cyclic sulfonamides with excellent yields and up to 99% ee.

Sign in / Sign up

Export Citation Format

Share Document