Palladium-catalyzed annulation of N-alkoxy benzsulfonamides with arynes by C–H functionalization: access to dibenzosultams

2019 ◽  
Vol 6 (4) ◽  
pp. 517-522 ◽  
Author(s):  
Simin Feng ◽  
Shan Li ◽  
Jing Li ◽  
Junfa Wei
Keyword(s):  
Bond Cleavage ◽  
Bond Formation ◽  
Palladium Catalyzed

Palladium-catalyzed C–H/N–H functionalization of N-alkoxy benzsulfonamides with arynes provides dibenzosultams via C–C/C–N bond formation, accompanied by an unexpected N–O bond cleavage.

Palladium-catalyzed C–S bond activation and functionalization of 3-sulfenylindoles and related electron-rich heteroarenes

2017 ◽  
Vol 4 (8) ◽  
pp. 1590-1594 ◽  
Author(s):  
Jianxiao Li ◽  
Yanni An ◽  
Jiawei Li ◽  
Shaorong Yang ◽  
Wanqing Wu ◽  
...  
Keyword(s):  
Bond Activation ◽  
Bond Cleavage ◽  
Bond Formation ◽  
Palladium Catalyzed

A novel palladium-catalyzed approach for constructing functionalized heteroarenes via C–S bond cleavage and C–C bond formation has been demonstrated.

Palladium-Catalyzed/Copper-Mediated Desulfurization and Aryl­­ation of Quinoline-2-(1H)-thione for Rapid Access to Quinoline Derivatives

Synthesis ◽  
2019 ◽  
Vol 52 (06) ◽  
pp. 893-900
Author(s):  
Hai-Long Lu ◽  
Fu-Hu Guo ◽  
Tong-Lin Wang ◽  
Xi-Cun Wang ◽  
Zheng-Jun Quan
Keyword(s):  
Bond Cleavage ◽  
Bond Formation ◽  
Inert Atmosphere ◽  
Single Step ◽  
Diverse Range ◽  
Arylboronic Acids ◽  
Carbon Carbon Bond ◽  
Substituted Quinolines ◽  
Wide Range ◽  
Palladium Catalyzed

An efficient method for carbon–carbon bond formation is described. The process employs the palladium-catalyzed and copper-mediated cross-coupling of quinoline-2-(1H)-thiones with arylboronic acids or alkynes through C–S bond cleavage without an inert atmosphere. The method provides rapid and general access to a diverse range of 2-substituted quinolines in a single step from a wide range of quinoline-2-(1H)-thiones and arylboronic acids or alkynes.

Palladium-Catalyzed C–C Bond Formation of Arylhydrazines with Olefins via Carbon–Nitrogen Bond Cleavage

2011 ◽  
Vol 13 (23) ◽  
pp. 6308-6311 ◽  
Author(s):  
Ming-Kui Zhu ◽  
Jun-Feng Zhao ◽  
Teck-Peng Loh
Keyword(s):  
Bond Cleavage ◽  
Bond Formation ◽  
Palladium Catalyzed ◽  
Nitrogen Bond

Cascade Access to Carboline Carboxylates from Indolyl Ketoximes and Acrylates via Palladium-Catalyzed C–H Bond Alkenylation/Annulation

Synlett ◽  
2020 ◽  
Vol 32 (01) ◽  
pp. 69-74 ◽  
Author(s):  
Cheng-Cai Xia ◽  
Ya-Fei Ji ◽  
Xiao-Pan Fu ◽  
Lu Chen ◽  
Gao-Rong Wu ◽  
...  
Keyword(s):  
Bond Cleavage ◽  
Bond Formation ◽  
Palladium Catalyzed

An efficient palladium-catalyzed C–H bond alkenylation/annulation strategy to access carboline carboxylates from indolyl ketoximes and acrylates through C–C/C–N bond formation is reported. Indolyl ketoximes not only direct ortho-olefination with acrylates, but also undergo an intramolecular N–O bond cleavage/traceless annulation to construct carboline carboxylates straightforwardly in this concise method.

Palladium-catalyzed cascade cyclizations involving C–C and C–X bond formation: strategic applications in natural product synthesis

2021 ◽  
Author(s):  
K. R. Holman ◽  
A. M. Stanko ◽  
S. E. Reisman
Keyword(s):  
Natural Product ◽  
Bond Formation ◽  
Natural Product Synthesis ◽  
Cascade Cyclizations ◽  
Palladium Catalyzed ◽  
Multiple Rings

This tutorial review highlights the use of palladium-catalyzed cascade cyclizations in natural product synthesis, focusing on cascades that construct multiple rings and form both C–C and C–X (X = O, N) bonds in a single synthetic operation.

Sign in / Sign up

Export Citation Format

Share Document