One-pot regioselective synthesis of 2,4-disubstituted quinolines via copper(ii)-catalyzed cascade annulation

2018 ◽  
Vol 5 (10) ◽  
pp. 1713-1718 ◽  
Author(s):  
Wenhao Wu ◽  
Yujuan Guo ◽  
Xuefeng Xu ◽  
Zhi Zhou ◽  
Xu Zhang ◽  
...  
Keyword(s):  
Regioselective Synthesis ◽  
One Pot ◽  
One Pot Synthesis ◽  
The One

A copper(ii)-catalyzed cascade annulation for the one-pot synthesis of 2,4-disubstituted quinolines has been disclosed.

Reaction of isatins with 6-amino uracils and isoxazoles: isatin ring-opening vs. annulations and regioselective synthesis of isoxazole fused quinoline scaffolds in water

2015 ◽  
Vol 17 (6) ◽  
pp. 3362-3372 ◽  
Author(s):  
Nataraj Poomathi ◽  
Sivakalai Mayakrishnan ◽  
Doraiswamy Muralidharan ◽  
Rajagopal Srinivasan ◽  
Paramasivan T. Perumal
Keyword(s):  
Ring Opening ◽  
Sulphonic Acid ◽  
Regioselective Synthesis ◽  
One Pot ◽  
One Pot Synthesis ◽  
The One ◽  
Straightforward Approach

A straightforward approach for the one-pot synthesis of isoxazoloquinoline and spiroxindole derivatives in water has been established using p-toluene sulphonic acid as a catalyst.

Expedient access to α,β-difunctionalized azepenes using α-halo eneformamides: application to the one-pot synthesis of 2-benzazepanes

2015 ◽  
Vol 13 (8) ◽  
pp. 2285-2292 ◽  
Author(s):  
Daniel P. Bassler ◽  
Laura Spence ◽  
Amir Alwali ◽  
Oliver Beale ◽  
Timothy K. Beng
Keyword(s):  
Regioselective Synthesis ◽  
One Pot ◽  
One Pot Synthesis ◽  
The One

The regioselective synthesis of α,β-difunctionalized (alkenyl, aryl, sulfonyl, allyl, or alkynyl) azepenes has been accomplished through α-halo eneformamides.

Two Efficient One-Pot Approaches for Regioselective Synthesis of New 3-Arylpyridazino[4,3-c]quinolin-5(6H)-ones

2015 ◽  
Vol 68 (10) ◽  
pp. 1529 ◽  
Author(s):  
Mehdi Rimaz
Keyword(s):  
Hydrazine Hydrate ◽  
Regioselective Synthesis ◽  
Reaction Conditions ◽  
One Pot ◽  
One Pot Synthesis ◽  
Three Component Reaction ◽  
The One ◽  
High Yields ◽  
Arylglyoxal Monohydrates ◽  
Operational Simplicity

Two efficient regioselective approaches for the one-pot synthesis of 3-arylpyridazino[4,3-c]quinolin-5(6H)-one derivatives are reported, by the three-component reaction of arylglyoxal monohydrates, quinoline-2,4-diol, and hydrazinium dihydrochloride or hydrazine hydrate in ethanol and pyridine. In ethanol, the reactions were catalyzed by 1,4-diazobicyclo[2,2,2]octane. The features of both procedures are high regioselectivity, mild reaction conditions, good to high yields, and operational simplicity.

An Overview of the One-pot Synthesis of Imidazolines

2020 ◽  
Vol 24 (20) ◽  
pp. 2341-2355
Author(s):  
Thaipparambil Aneeja ◽  
Sankaran Radhika ◽  
Mohan Neetha ◽  
Gopinathan Anilkumar
Keyword(s):  
Asymmetric Catalysis ◽  
Organic Compounds ◽  
Ring Opening ◽  
Ecological Impact ◽  
Chiral Auxiliary ◽  
One Pot ◽  
One Pot Synthesis ◽  
The One ◽  
Synthetic Intermediate ◽  
Heterocyclic Moiety

One-pot syntheses are a simple, efficient and easy methodology, which are widely used for the synthesis of organic compounds. Imidazoline is a valuable heterocyclic moiety used as a synthetic intermediate, chiral auxiliary, chiral catalyst and a ligand for asymmetric catalysis. Imidazole is a fundamental unit of biomolecules that can be easily prepared from imidazolines. The one-pot method is an impressive approach to synthesize organic compounds as it minimizes the reaction time, separation procedures, and ecological impact. Many significant one-pot methods such as N-bromosuccinimide mediated reaction, ring-opening of tetrahydrofuran, triflic anhydrate mediated reaction, etc. were reported for imidazoline synthesis. This review describes an overview of the one-pot synthesis of imidazolines and covers literature up to 2020.

Convenient One-Pot Synthesis of α-Selenonitriles, α-Selenoesters and Asymmetrical Selenides by a Sm/ZnCl2 system in DMF-H2O

2001 ◽  
Vol 2001 (4) ◽  
pp. 160-161 ◽  
Author(s):  
Hongyun Guo ◽  
Yunfa Zheng ◽  
Yongmin Zhang
Keyword(s):  
One Pot ◽  
One Pot Synthesis ◽  
Organic Halides ◽  
The One

α-Selenonitriles, α-selenoesters, and asymmetrical selenides can be readily obtained from the one-pot reaction of diselenides and active organic halides by a Sm/ZnCl2 system in DMF-H2O.

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