scholarly journals Amplified antimicrobial action of chlorhexidine encapsulated in PDAC-functionalized acrylate copolymer nanogel carriers

2018 ◽  
Vol 2 (11) ◽  
pp. 2032-2044 ◽  
Author(s):  
Mohammed J. Al-Awady ◽  
Paul J. Weldrick ◽  
Matthew J. Hardman ◽  
Gillian M. Greenway ◽  
Vesselin N. Paunov

We demonstrate a strong enhancement of the antimicrobial action of chlorhexidine which is attributed to the electrostatic adhesion of the cationic nanocarriers on the microbial cell walls which leads to their accumulation and local delivery of chlorhexidine directly on to the microbial cell membrane.

2019 ◽  
Vol 1 (2) ◽  
pp. 858-872 ◽  
Author(s):  
Saba S. M. Al-Obaidy ◽  
Gillian M. Greenway ◽  
Vesselin N. Paunov

We demonstrate a strong enhancement of the antimicrobial action of berberine encapsulated in shellac nanoparticles with dual surface functionality. This is attributed to the electrostatic adhesion of the cationic nanocarriers to the microbial cell walls which leads to their accumulation and local delivery of berberine.


2019 ◽  
Vol 7 (19) ◽  
pp. 3119-3133 ◽  
Author(s):  
Saba S. M. Al-Obaidy ◽  
Ahmed F. Halbus ◽  
Gillian M. Greenway ◽  
Vesselin N. Paunov

We demonstrate a strong enhancement of the antimicrobial action of vancomycin encapsulated in shellac nanocarriers with cationic surface functionality which concentrate on the microbial cell membranes.


JAMA ◽  
1961 ◽  
Vol 178 (4) ◽  
pp. 415
Keyword(s):  

2021 ◽  
Vol 1 (1) ◽  
Author(s):  
Joana Séneca ◽  
Andrea Söllinger ◽  
Craig W. Herbold ◽  
Petra Pjevac ◽  
Judith Prommer ◽  
...  

AbstractGlobal warming increases soil temperatures and promotes faster growth and turnover of soil microbial communities. As microbial cell walls contain a high proportion of organic nitrogen, a higher turnover rate of microbes should also be reflected in an accelerated organic nitrogen cycling in soil. We used a metatranscriptomics and metagenomics approach to demonstrate that the relative transcription level of genes encoding enzymes involved in the extracellular depolymerization of high-molecular-weight organic nitrogen was higher in medium-term (8 years) and long-term (>50 years) warmed soils than in ambient soils. This was mainly driven by increased levels of transcripts coding for enzymes involved in the degradation of microbial cell walls and proteins. Additionally, higher transcription levels for chitin, nucleic acid, and peptidoglycan degrading enzymes were found in long-term warmed soils. We conclude that an acceleration in microbial turnover under warming is coupled to higher investments in N acquisition enzymes, particularly those involved in the breakdown and recycling of microbial residues, in comparison with ambient conditions.


1992 ◽  
pp. 397-407
Author(s):  
Shigehiro Hirano ◽  
Hiroshi Inui ◽  
Hideto Kosake ◽  
Keiko Tabata ◽  
Yoshitaka Uno

JAMA ◽  
1961 ◽  
Vol 177 (8) ◽  
pp. 587
Author(s):  
George Halperin
Keyword(s):  

2020 ◽  
Vol 31 (21) ◽  
pp. 2306-2314
Author(s):  
Ting Gang Chew ◽  
Tzer Chyn Lim ◽  
Yumi Osaki ◽  
Junqi Huang ◽  
Anton Kamnev ◽  
...  

This manuscript investigates cytokinesis in fission yeast spheroplasts and reports that the extracellular matrix inhibits division site ingression and that new septum synthesis relieves this inhibition. The work also shows the importance of the actomyosin ring and membrane secretion in spheroplast division.


Author(s):  
Milton R. J. Salton
Keyword(s):  

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