scholarly journals Crosslinked casein-based micelles as a dually responsive drug delivery system

2018 ◽  
Vol 9 (25) ◽  
pp. 3499-3510 ◽  
Author(s):  
Matias Luis Picchio ◽  
Julio César Cuggino ◽  
Gregor Nagel ◽  
Stefanie Wedepohl ◽  
Roque Javier Minari ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Drug Carrier ◽  
Hydrophobic Drug ◽  
Triggered Release ◽  
Casein Micelles ◽  
Carrier Material ◽  
System P

Crosslinked casein micelles with a dual pH and protease drug triggered release can be applied as a promising hydrophobic drug carrier material.

Magnetic proline-based ionic liquid surfactant as a nano-carrier for hydrophobic drug delivery

2020 ◽  
Vol 8 (15) ◽  
pp. 3050-3057 ◽  
Author(s):  
Akshay Kulshrestha ◽  
Praveen Singh Gehlot ◽  
Arvind Kumar
Keyword(s):  
Drug Delivery ◽  
Ionic Liquid ◽  
Drug Delivery System ◽  
Delivery System ◽  
Hydrophobic Drug ◽  
System P ◽  
Ionic Liquid Surfactant

Biofriendly and magnetic proline based ionic liquid surfactant demonstrated for drug delivery system.

scholarly journals Pluronic F127 self-assembled MoS2 nanocomposites as an effective glutathione responsive anticancer drug delivery system

RSC Advances ◽  
2019 ◽  
Vol 9 (44) ◽  
pp. 25592-25601 ◽  
Author(s):  
Adhisankar Vadivelmurugan ◽  
Rajeshkumar Anbazhagan ◽  
Vinothini Arunagiri ◽  
Juin-Yih Lai ◽  
Hsieh-Chih Tsai
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Drug Delivery System ◽  
Anticancer Drug ◽  
Delivery System ◽  
Drug Carrier ◽  
Pluronic F127 ◽  
Anticancer Drug Delivery ◽  
System P ◽  
Self Assembled

In this study, bio-responsive polymeric MoS2 nanocomposites were prepared for use as a drug carrier for cancer therapy.

A bio-inspired fluorescent nano-injectable hydrogel as a synergistic drug delivery system

2021 ◽  
Vol 45 (6) ◽  
pp. 3079-3087
Author(s):  
Yue Xu ◽  
Mingming Yang ◽  
Qiyue Ma ◽  
Xiang Di ◽  
Guolin Wu
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Fluorescence Properties ◽  
Injectable Hydrogel ◽  
Sequential Release ◽  
System P

A nano-injectable hydrogel with fluorescence properties and controlled sequential release of dual drugs.

A novel injectable local hydrophobic drug delivery system: Biodegradable nanoparticles in thermo-sensitive hydrogel

2008 ◽  
Vol 359 (1-2) ◽  
pp. 228-233 ◽  
Author(s):  
MaLing Gou ◽  
XingYi Li ◽  
Mei Dai ◽  
ChangYang Gong ◽  
XianHuo Wang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Hydrophobic Drug ◽  
Biodegradable Nanoparticles

scholarly journals Carboxymethyl cellulose-grafted graphene oxide for efficient antitumor drug delivery

2018 ◽  
Vol 7 (4) ◽  
pp. 291-301 ◽  
Author(s):  
Zepeng Jiao ◽  
Bin Zhang ◽  
Chunya Li ◽  
Weicong Kuang ◽  
Jingxian Zhang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Graphene Oxide ◽  
Drug Delivery System ◽  
Delivery System ◽  
Carboxymethyl Cellulose ◽  
Drug Carrier ◽  
Controlled Drug Release ◽  
Ph Sensitive ◽  
Tumor Growth Inhibition

Abstract A drug delivery system based on carboxymethyl cellulose-grafted graphene oxide loaded by methotrexate (MTX/CMC-GO) with pH-sensitive and controlled drug-release properties was developed in this work. CMC was grafted on graphene oxide by ethylenediamine through hydrothermal treatment. CMC serves as a pH-sensitive trigger, while CMC-GO serves as a drug-carrying vehicle due to the curved layer and large plain surface. Different amounts of drugs could be loaded into CMC-GO nanocarriers by control of the original amount of drug/carrier ratios. Additionally, low cytotoxicity against NIH-3T3 cells and low in vivo toxicity was observed. In vivo tumor growth inhibition assays showed that MTX/CMC-GO demonstrated superior antitumor activity than free MTX against HT-29 cells. Moreover, prolonged survival time of mice was observed after MTX/CMC-GO administration. The MTX/CMC-GO drug delivery system has a great potential in colon cancer therapy.

scholarly journals Development and in vitro Evaluation of Gastro-protective Aceclofenac-loaded Self-emulsifying Drug Delivery System

2020 ◽  
Vol Volume 15 ◽  
pp. 5217-5226 ◽  
Author(s):  
Chen Jianxian ◽  
Kalsoom Saleem ◽  
Muhammad Ijaz ◽  
Masood Ur-Rehman ◽  
Ghulam Murtaza ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
In Vitro Evaluation ◽  
System P

scholarly journals Self-assembled pH-responsive supramolecular hydrogel for hydrophobic drug delivery

RSC Advances ◽  
2018 ◽  
Vol 8 (55) ◽  
pp. 31581-31587 ◽  
Author(s):  
Lin Wang ◽  
Xuefeng Shi ◽  
Jian Zhang ◽  
Yuejun Zhu ◽  
Jinben Wang
Keyword(s):  
Drug Delivery ◽  
Cancer Cells ◽  
Drug Delivery System ◽  
Delivery System ◽  
Hydrophobic Drug ◽  
Ph Responsive ◽  
Supramolecular Hydrogel ◽  
Self Assembled

Supramolecular hydrogel, AGC16/NTS, was used to encapsulate hydrophobic drug curcumin (Cur), constructing a pH-responsive drug delivery system; the uptake of released Cur by cancer cells also occurred.

Development of a microdevice-based human mesenchymal stem cell-mediated drug delivery system

2019 ◽  
Vol 7 (6) ◽  
pp. 2348-2357 ◽  
Author(s):  
Junfei Xia ◽  
Ang-Chen Tsai ◽  
Wenhao Cheng ◽  
Xuegang Yuan ◽  
Teng Ma ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Stem Cell ◽  
Mesenchymal Stem Cell ◽  
Drug Delivery System ◽  
Delivery System ◽  
Drug Delivery Systems ◽  
Human Mesenchymal Stem Cell ◽  
Living Cells ◽  
Controlled Delivery ◽  
System P

Cell-mediated drug delivery systems utilize living cells as vehicles to achieve controlled delivery of drugs.

scholarly journals Size and charge dual-transformable mesoporous nanoassemblies for enhanced drug delivery and tumor penetration

2020 ◽  
Vol 11 (10) ◽  
pp. 2819-2827 ◽  
Author(s):  
Liang Chen ◽  
Tiancong Zhao ◽  
Mengyao Zhao ◽  
Wenxing Wang ◽  
Caixia Sun ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Tumor Penetration ◽  
Biological Barriers ◽  
System P

Size and charge dual-transformable core@satellite structured nanoassemblies are developed to overcome multiple biological barriers in a drug delivery system.

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