Stereoselective synthesis of a phosphonate pThr mimetic via palladium-catalyzed γ-C(sp3)–H activation for peptide preparation

Hua-Zhen Duan; Hong-Xue Chen; Qing Yu; Jun Hu; Yan-Mei Li; Yong-Xiang Chen

doi:10.1039/c8ob02999g

Stereoselective synthesis of a phosphonate pThr mimetic via palladium-catalyzed γ-C(sp3)–H activation for peptide preparation

Organic & Biomolecular Chemistry ◽

10.1039/c8ob02999g ◽

2019 ◽

Vol 17 (8) ◽

pp. 2099-2102 ◽

Cited By ~ 4

Author(s):

Hua-Zhen Duan ◽

Hong-Xue Chen ◽

Qing Yu ◽

Jun Hu ◽

Yan-Mei Li ◽

...

Keyword(s):

Stereoselective Synthesis ◽

Synthetic Strategy ◽

Palladium Catalyzed ◽

Peptide Preparation

We report a facile and efficient synthetic strategy toward a CH2-substituted phosphonate pThr mimetic and its application in phosphopeptide inhibitor synthesis.

Download Full-text

Faculty Opinions recommendation of A stereoselective synthesis of digitoxin and digitoxigen mono- and bisdigitoxoside from digitoxigenin via a palladium-catalyzed glycosylation.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1040636.489647 ◽

2006 ◽

Author(s):

Jon Thorson

Keyword(s):

Stereoselective Synthesis ◽

Palladium Catalyzed

Download Full-text

Palladium-Catalyzed Stereoselective Synthesis of Multisubstituted Allenes and Their Application in Organic Transformations

Journal of Synthetic Organic Chemistry Japan ◽

10.5059/yukigoseikyokaishi.66.100 ◽

2008 ◽

Vol 66 (2) ◽

pp. 100-109 ◽

Cited By ~ 5

Author(s):

Masamichi Ogasawara

Keyword(s):

Stereoselective Synthesis ◽

Organic Transformations ◽

Palladium Catalyzed

Download Full-text

ChemInform Abstract: Stereoselective Synthesis of Difunctionalized 1,3-Dienes Containing Tin and Sulfonyl Groups by Palladium-Catalyzed Regio- and Stereocontrolled Addition Reactions.

ChemInform ◽

10.1002/chin.201223061 ◽

2012 ◽

Vol 43 (23) ◽

pp. no-no

Author(s):

Hong Zhao ◽

Weisen Yang ◽

Shiyun Xie ◽

Mingzhong Cai

Keyword(s):

Stereoselective Synthesis ◽

Addition Reactions ◽

Palladium Catalyzed

Download Full-text

Stereoselective Synthesis of ( Z )‐Dihomoallylic Phosphonates with Quaternary Carbon Center by Palladium‐Catalyzed Bisallylation of Vinylethyene Carbonates with β ‐Ketophosphonates

Asian Journal of Organic Chemistry ◽

10.1002/ajoc.202100054 ◽

2021 ◽

Author(s):

Zhigang Liu ◽

Miaolin Ke ◽

Ke Zhang ◽

Sheng Zuo ◽

Meifen Jiang ◽

...

Keyword(s):

Stereoselective Synthesis ◽

Quaternary Carbon ◽

Palladium Catalyzed

Download Full-text

Stereoselective Synthesis of 1,3-Dienylstannanes by Palladium Catalyzed Cross-Coupling Reactions.

ChemInform ◽

10.1002/chin.200416155 ◽

2004 ◽

Vol 35 (16) ◽

Author(s):

Mingzhong Cai ◽

Hongde Ye ◽

Hong Zhao ◽

Caisheng Song

Keyword(s):

Stereoselective Synthesis ◽

Cross Coupling ◽

Coupling Reactions ◽

Cross Coupling Reactions ◽

Palladium Catalyzed

Download Full-text

ChemInform Abstract: N-Boc-α-tosylsarcosine Ethyl Ester: An α-Amido Sulfone for the Regio- and Stereoselective Synthesis of Protected γ,δ-Unsaturated N-Methyl-α-amino Acids by Palladium-Catalyzed Nucleophilic Substitution.

ChemInform ◽

10.1002/chin.199806228 ◽

2010 ◽

Vol 29 (6) ◽

pp. no-no

Author(s):

D. A. ALONSO ◽

A. COSTA ◽

C. NAJERA

Keyword(s):

Amino Acids ◽

Nucleophilic Substitution ◽

Ethyl Ester ◽

Stereoselective Synthesis ◽

Palladium Catalyzed

Download Full-text

Regio- and Stereoselective Synthesis of 2-Deoxy-C-aryl Glycosides via Palladium Catalyzed Decarboxylative Reactions

Organic Letters ◽

10.1021/ol201820m ◽

2011 ◽

Vol 13 (17) ◽

pp. 4608-4611 ◽

Cited By ~ 67

Author(s):

Shaohua Xiang ◽

Shuting Cai ◽

Jing Zeng ◽

Xue-Wei Liu

Keyword(s):

Stereoselective Synthesis ◽

Palladium Catalyzed ◽

Aryl Glycosides

Download Full-text

Stereoselective Synthesis of β-Alkylated α-Amino Acids via Palladium-Catalyzed Alkylation of Unactivated Methylene C(sp3)–H Bonds with Primary Alkyl Halides

Journal of the American Chemical Society ◽

10.1021/ja406484v ◽

2013 ◽

Vol 135 (32) ◽

pp. 12135-12141 ◽

Cited By ~ 251

Author(s):

Shu-Yu Zhang ◽

Qiong Li ◽

Gang He ◽

William A. Nack ◽

Gong Chen

Keyword(s):

Amino Acids ◽

Stereoselective Synthesis ◽

Alkyl Halides ◽

Palladium Catalyzed

Download Full-text

Palladium‐Catalyzed C−H Alkenylation of Arenes with Alkynes: Stereoselective Synthesis of Vinyl Chlorides via a 1,4‐Chlorine Migration

Angewandte Chemie International Edition ◽

10.1002/anie.201808866 ◽

2018 ◽

Vol 57 (49) ◽

pp. 16041-16045 ◽

Cited By ~ 5

Author(s):

Zhen Li ◽

Wei‐Liang Duan

Keyword(s):

Stereoselective Synthesis ◽

Palladium Catalyzed

Download Full-text

ChemInform Abstract: Synthesis of 1,3-Oxazine Derivatives by Palladium-Catalyzed Cycloaddition of Vinyloxetanes with Heterocumulenes. Completely Stereoselective Synthesis of Bicyclic 1,3-Oxazines.

ChemInform ◽

10.1002/chin.199938155 ◽

2010 ◽

Vol 30 (38) ◽

pp. no-no

Author(s):

Chitchamai Larksarp ◽

Howard Alper

Keyword(s):

Stereoselective Synthesis ◽

Palladium Catalyzed ◽

Oxazine Derivatives

Download Full-text