Aza-tricycles containing a perfluoroalkyl group: synthesis, structure and fluorescence

2018 ◽  
Vol 16 (46) ◽  
pp. 8950-8954 ◽  
Author(s):  
Qiang Fu ◽  
Rui Wang ◽  
Fushun Liang ◽  
Wei Guan

Perfluoroalkyl-containing aza-tricycles have been prepared in one synthetic operation via an ambient light-promoted three-component reaction of β-oxo esters, perfluoroalkyl iodide and DBU.

2020 ◽  
pp. 87-97
Author(s):  
Sourish Chatterjee ◽  
Biswanath Roy

In an office space, an LED-based lighting system allows you to perform the function of a data transmitter. This article discusses the cost-effective design and development of a data-enabled LED driver that can transmit data along with its receiving part. In addition, this paper clearly outlines the application of the proposed VLC system in an office environment where ambient light interference is a severe issue of concern. The result shows satisfactory lighting characteristics in general for this area in terms of average horizontal illuminance and illuminance uniformity. At the same time, to evaluate real-time and static communication performance, Arduino interfaced MATLAB Simulink model is developed, which shows good communication performance in terms of BER (10–7) even in presence of ambient light noise with 6 dB signal to interference plus noise ratio. Our designed system is also flexible to work as a standalone lighting system, whenever data communication is not required.


2010 ◽  
Vol E93-C (11) ◽  
pp. 1583-1589
Author(s):  
Fumirou MATSUKI ◽  
Kazuyuki HASHIMOTO ◽  
Keiichi SANO ◽  
Fu-Yuan HSUEH ◽  
Ramesh KAKKAD ◽  
...  

2019 ◽  
Vol E102.C (7) ◽  
pp. 558-564
Author(s):  
Takashi NAKAMURA ◽  
Masahiro TADA ◽  
Hiroyuki KIMURA

2019 ◽  
Author(s):  
Benjamin Lipp ◽  
Lisa Marie Kammer ◽  
Murat Kucukdisli ◽  
Adriana Luque ◽  
Jonas Kühlborn ◽  
...  

Simultaneous sulfonylation/arylation of styrene derivatives is achieved in a photoredox-catalyzed three-component reaction using visible light. A broad variety of difunctionalized products is accessible in mostly excellent yields and high diastereoselectivity. The developed reaction is scalable and suitable for the modification of styrene-functionalized biomolecules. Mechanistic investigations suggest the transformation to be operating through a designed sequence of radical formation and radical combination.<br>


2020 ◽  
Vol 17 ◽  
Author(s):  
Mehdi Abaszadeh ◽  
Seyyed Jalal Roudbaraki ◽  
Hossein Yarahmadi ◽  
Majid Ghashang

: Silica-POCl2 was used as the promoter for the three-component reaction of ethyl/methyl 3-phenyl glycidate, aniline derivatives, and dimethylcarbonate, leads to the synthesis of methyl/ethyl 2-oxo-4-phenyl-3-aryloxazolidine-5-carboxylate derivatives. The desired product was obtained in high yields.


2020 ◽  
Vol 17 ◽  
Author(s):  
Visarapu Malathi ◽  
Pedavenkatagari Narayana Reddy ◽  
Pannala Padmaja

Abstract:: An efficient method has been developed for the synthesis of new pyrano[3,2-c] and pyrano[3,2-a]carbazole de-rivatives via a three component reaction of 4-hydroxycarbazole or 2-hydroxycarbazole, isocyanides, and dialkylacetylenedi-carboxylates. Noteworthy features of this protocol include mild reaction conditions, catalyst-free, high atom-economy and high yields.


2019 ◽  
Vol 19 (2) ◽  
pp. 265-275 ◽  
Author(s):  
Faeze Khalili ◽  
Sara Akrami ◽  
Malihe Safavi ◽  
Maryam Mohammadi-Khanaposhtani ◽  
Mina Saeedi ◽  
...  

Background: This paper reports synthesis, cytotoxic activity, and apoptosis inducing effect of a novel series of styrylimidazo[1,2-a]pyridine derivatives. Objective: In this study, anti-cancer activity of novel styrylimidazo[1,2-a]pyridines was evaluated. Methods: Styrylimidazo[1,2-a]pyridine derivatives 4a-o were synthesized through a one-pot three-component reaction of 2-aminopyridines, cinnamaldehydes, and isocyanides in high yield. All synthesized compounds 4a-o were evaluated against breast cancer cell lines including MDA-MB-231, MCF-7, and T-47D using MTT assay. Apoptosis was evaluated by acridine orange/ethidium bromide staining, cell cycle analysis, and TUNEL assay as the mechanism of cell death. Results: Most of the synthesized compounds exhibited more potent cytotoxicity than standard drug, etoposide. Induction of apoptosis by the most cytotoxic compounds 4f, 4g, 4j, 4n, and 4m was confirmed through mentioned methods. Conclusion: In conclusion, these results confirmed the potency of styrylimidazo[1,2-a]pyridines for further drug discovery developments in the field of anti-cancer agents.


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