Synthesis and potassium KV7 channel opening activity of thioether analogues of the analgesic flupirtine

2018 ◽  
Vol 16 (45) ◽  
pp. 8695-8699 ◽  
Author(s):  
Christian Bock ◽  
Kristin Beirow ◽  
Abdrrahman S. Surur ◽  
Lukas Schulig ◽  
Anja Bodtke ◽  
...  
Keyword(s):  
Potassium Channel ◽  
Oxidation Products ◽  
Potassium Channel Opener ◽  
Channel Opener ◽  
Channel Opening

Benign by design: active sulfide-analogues of potassium channel opener flupirtine do not form reactive oxidation products in vitro.

scholarly journals Pharmacological property of a new potassium channel opener, TCV-295 in vitro.

1993 ◽  
Vol 61 ◽  
pp. 220
Author(s):  
Yumiko Awane ◽  
Keiji Kusumoto ◽  
Shouhei Hashiguchi ◽  
Mitsuru Shiraishi ◽  
Toshifumi Watanabe
Keyword(s):  
Potassium Channel ◽  
Pharmacological Property ◽  
Potassium Channel Opener ◽  
Channel Opener

Effects of the New Potassium Channel Opener JTV-506 on Coronary Vessels in vitro and in vivo

2011 ◽  
Vol 49 (03) ◽  
pp. 199-206
Author(s):  
Yukiya Hirata ◽  
Atsunori Kanada ◽  
Hisato Miyai ◽  
Yukiyo Mabuchi ◽  
Kazuo Aisaka
Keyword(s):  
Potassium Channel ◽  
Coronary Vessels ◽  
Potassium Channel Opener ◽  
Channel Opener

The Synthesis and Use of BMS 204352 (MaxiPostTM)

2020 ◽  
Vol 17 (1) ◽  
pp. 67-73
Author(s):  
Renato Dalpozzo
Keyword(s):  
Potassium Channel ◽  
The State ◽  
Synthetic Methods ◽  
Potassium Channel Opener ◽  
Research Fields ◽  
Channel Opener ◽  
In Vivo Tests ◽  
State Of Art

MaxiPostTM is an interesting 3-fluorooxindole derivative, discovered in the late nineties of the last century as potassium channel opener. Since then, two different research fields were discovered: the discovery of new synthetic methods, especially asymmetric ones, and the in vitro and in vivo tests for its use as a drug for different diseases. This mini-review aims to summarize the state of art in both fields.

Airway pharmacology of the potassium channel opener, HOE 234, in guinea pigs: in vitro and in vivo studies

1992 ◽  
Vol 210 (1) ◽  
pp. 69-75 ◽  
Author(s):  
Heinrich C. Englert ◽  
Klaus Wirth ◽  
Doris Gehring ◽  
Ute Fürst ◽  
Udo Albus ◽  
...  
Keyword(s):  
Potassium Channel ◽  
Guinea Pigs ◽  
In Vivo Studies ◽  
Potassium Channel Opener ◽  
Channel Opener

EFFECTS OF THE POTASSIUM CHANNEL OPENER AND NITRIC OXIDE DONOR NICORANDIL ON THE URETER MOTILITY OF PIGS IN VITRO AND IN VIVO

1999 ◽  
pp. 86
Author(s):  
Hansjorg Danuser ◽  
Ruth Weiss ◽  
Meike Mevissen ◽  
Daniela Abel ◽  
Gunter Scholtysik ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Potassium Channel ◽  
Nitric Oxide Donor ◽  
Potassium Channel Opener ◽  
Channel Opener

scholarly journals Bronchodilating effects of the novel potassium channel opener HOE 234 in human airways in vitro.

1993 ◽  
Vol 35 (3) ◽  
pp. 318-320 ◽  
Author(s):  
M. Miura ◽  
MG Belvisi ◽  
JK Ward ◽  
S. Tadjkarimi ◽  
MH Yacoub ◽  
...  
Keyword(s):  
Potassium Channel ◽  
The Novel ◽  
Potassium Channel Opener ◽  
Channel Opener ◽  
Human Airways
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