Tunable synthesis of quinolinone-fused isoquinolines through sequential one-pot nucleophilic addition and palladium-catalyzed intramolecular C–H alkenylation

2019 ◽  
Vol 17 (2) ◽  
pp. 321-332 ◽  
Author(s):  
Xue Li ◽  
Yunyun Bian ◽  
Xin Chen ◽  
Hang Zhang ◽  
Wei Wang ◽  
...  
Keyword(s):  
Nucleophilic Addition ◽  
One Pot ◽  
One Pot Synthesis ◽  
Fused Heterocycles ◽  
Biological Interest ◽  
Palladium Catalyzed

An efficient sequential one-pot synthesis of N-fused heterocycles based on 4-quinolinone and isoquinoline scaffolds of biological interest has been developed.

Palladium-Catalyzed One-Pot Synthesis of C2-Quaternary Indolin-3-ones via 1H -indole-3-sulfonates Generated in Situ from 2-Alkynyl Arylazides and Sulfonic Acids

2017 ◽  
Vol 359 (23) ◽  
pp. 4147-4152 ◽  
Author(s):  
Xiaoxiang Zhang ◽  
Ping Li ◽  
Chang Lyu ◽  
Wanxiong Yong ◽  
Jing Li ◽  
...  
Keyword(s):  
Sulfonic Acids ◽  
One Pot ◽  
One Pot Synthesis ◽  
Palladium Catalyzed

ChemInform Abstract: One-Pot Synthesis of Arylketones from Aromatic Acids via Palladium-Catalyzed Suzuki Coupling.

ChemInform ◽  
2016 ◽  
Vol 47 (32) ◽  
Author(s):  
Hongxiang Wu ◽  
Baiping Xu ◽  
Yue Li ◽  
Fengying Hong ◽  
Dezhao Zhu ◽  
...  
Keyword(s):  
Suzuki Coupling ◽  
Aromatic Acids ◽  
One Pot ◽  
One Pot Synthesis ◽  
Palladium Catalyzed

Palladium-Catalyzed One-Pot Stereospecific Synthesis of 2-Deoxy Aryl C-Glycosides from Glycals and Anilines in the Presence of tert-Butyl Nitrite

Synthesis ◽  
2019 ◽  
Vol 51 (22) ◽  
pp. 4215-4230 ◽  
Author(s):  
Adesh Kumar Singh ◽  
Rapelly Venkatesh ◽  
Jeyakumar Kandasamy
Keyword(s):  
Room Temperature ◽  
Stereospecific Synthesis ◽  
One Pot ◽  
Tert Butyl ◽  
Mild Conditions ◽  
One Pot Synthesis ◽  
Palladium Catalyzed ◽  
Aryl Glycosides

The palladium-catalyzed one-pot synthesis of 2,3-deoxy-3-keto aryl C-glycosides is achieved from glycals and anilines in the presence of tert-butyl nitrite and aqueous HBF4 under mild conditions. This one-pot method stereospecifically provides α- and β-aryl glycosides (≥19:1 by NMR) in good yields at room temperature. The configuration at the C-3 position in the glycal determines the anomeric selectivity (i.e., α or β) of the desired products.

scholarly journals Convenient One-Pot Synthesis of Allylsilanes from Enolizable Ketones

SynOpen ◽  
2019 ◽  
Vol 03 (04) ◽  
pp. 138-141
Author(s):  
Man Lung D. Kwan ◽  
Paul R. Challen ◽  
Quynh D.-D. Tran
Keyword(s):  
Nucleophilic Addition ◽  
Slight Modification ◽  
Second Step ◽  
One Pot ◽  
One Pot Synthesis ◽  
Aryl Ketones

A convenient one-pot synthesis of allylsilanes from enolizable methyl aryl ketones has been developed. The first step involves nucleophilic addition of the trimethylsilylmethyl group to ketones using the alkylation method developed by Ishihara with slight modification to generate the corresponding β-silylalkoxides. The second step entails addition of diisobutylaluminum chloride and heating at about 130 °C overnight to afford allylsilanes in fair yields.

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