Highly sulphated cellulose: a versatile, reusable and selective desilylating agent for deprotection of alcoholic TBDMS ethers

2018 ◽  
Vol 16 (33) ◽  
pp. 6057-6062 ◽  
Author(s):  
Soma Shekar Dachavaram ◽  
Narsimha R. Penthala ◽  
Julie L. Calahan ◽  
Eric J. Munson ◽  
Peter A. Crooks
Keyword(s):  
Cellulose Sulphate

A mild, effcient protocol was developed for the deprotection of alcoholic TBDMS ethers using highly sulphated HS-cellulose sulphate catalyst, which selectively cleaves alcoholic TBDMS ethers in bis-TBDMS ethers containing both alcoholic and phenolic TBDMS ether moieties.

scholarly journals Systemic long-term delivery of antibodies in immunocompetent animals using cellulose sulphate capsules containing antibody-producing cells

Gene Therapy ◽  
1998 ◽  
Vol 5 (6) ◽  
pp. 828-834 ◽  
Author(s):  
M Pelegrin ◽  
M Marin ◽  
D Noël ◽  
M Del Rio ◽  
R Saller ◽  
...  
Keyword(s):  
Term Delivery ◽  
Cellulose Sulphate

scholarly journals CHANGES IN PLASMA KININOGEN LEVELS INDUCED BY CELLULOSE SULPHATE DURING PREGNANCY IN THE RAT

1974 ◽  
Vol 52 (4) ◽  
pp. 533-537 ◽  
Author(s):  
J.T. McCORMICK ◽  
JUDITH SENIOR ◽  
E.T. WHALLEY
Keyword(s):  
Cellulose Sulphate

scholarly journals Efficient Protection of Probiotics for Delivery to the gastric tract by Cellulose Sulphate Encapsulation

2020 ◽  
Author(s):  
Walter Henry Gunzburg ◽  
Myo Myint Aung ◽  
Pauline Toa ◽  
Shirelle Ng ◽  
Eliot Read ◽  
...  
Keyword(s):  
Gut Microbiota ◽  
Oral Delivery ◽  
Cell Encapsulation ◽  
Fecal Microbiome ◽  
Stomach Acid ◽  
Health Promoting ◽  
A Cell ◽  
Efficient Protection ◽  
Cellulose Sulphate ◽  
And Storage

Abstract Gut microbiota in humans and animals play an important role in health, aiding in digestion, regulation of the immune system and protection against pathogens. Changes or imbalances in the gut microbiota (dysbiosis) have been linked to a variety of local and systemic diseases, and there is growing evidence that restoring the balance of the microbiota can restore health. This can be achieved by oral delivery of members of the microbiome (including probiotics) or by fecal microbiome transplantation. In order to provide their health promoting effects, microbiota must survive (i) transport and storage (i.e. shelf life) and (ii) transit through the highly acid conditions in the stomach and bile salts in the small intestine. We have developed a cell encapsulation technology based on the natural polymer, cellulose sulphate (CS) that protects members of the microbiota from stomach acid and bile.

Sign in / Sign up

Export Citation Format

Share Document