Enantioselective total synthesis and biological evaluation of (−)-solanacol

2018 ◽  
Vol 16 (30) ◽  
pp. 5500-5507 ◽  
Author(s):  
L. J. Bromhead ◽  
A. R. Norman ◽  
K. C. Snowden ◽  
B. J. Janssen ◽  
C. S. P. McErlean
Keyword(s):  
Total Synthesis ◽  
Phenyl Ring ◽  
Biological Evaluation ◽  
Enantioselective Synthesis ◽  
Enantioselective Total Synthesis ◽  
Synthesis And Biological Evaluation

An enantioselective synthesis of the phenyl ring-containing strioglactone, (−)-solanocol, is described.

scholarly journals Enantioselective Total Synthesis and Biological Evaluation of (+)-Kibdelone A and a Tetrahydroxanthone Analogue

2013 ◽  
Vol 78 (15) ◽  
pp. 7617-7626 ◽  
Author(s):  
Dana K. Winter ◽  
Mary Ann Endoma-Arias ◽  
Tomas Hudlicky ◽  
John A. Beutler ◽  
John A. Porco
Keyword(s):  
Total Synthesis ◽  
Biological Evaluation ◽  
Enantioselective Total Synthesis ◽  
Synthesis And Biological Evaluation

scholarly journals Xylochemical Synthesis and Biological Evaluation of Shancigusin C and Bletistrin G

Molecules ◽  
2021 ◽  
Vol 26 (11) ◽  
pp. 3224
Author(s):  
Leander Geske ◽  
Ulrich Kauhl ◽  
Mohamed E. M. Saeed ◽  
Anja Schüffler ◽  
Eckhard Thines ◽  
...  
Keyword(s):  
Total Synthesis ◽  
Biological Activities ◽  
Biological Evaluation ◽  
Aromatic Substitution ◽  
Substitution Reactions ◽  
Total Syntheses ◽  
Wittig Olefination ◽  
Starting Point ◽  
Perkin Reaction ◽  
Synthesis And Biological Evaluation

The biological activities of shancigusin C (1) and bletistrin G (2), natural products isolated from orchids, are reported along with their first total syntheses. The total synthesis of shancigusin C (1) was conducted by employing the Perkin reaction to forge the central stilbene core, whereas the synthesis of bletistrin G (2) was achieved by the Wittig olefination followed by several regioselective aromatic substitution reactions. Both syntheses were completed by applying only renewable starting materials according to the principles of xylochemistry. The cytotoxic properties of shancigusin C (1) and bletistrin G (2) against tumor cells suggest suitability as a starting point for further structural variation.

Total synthesis and biological evaluation of Wewakazole

2017 ◽  
Vol 33 (6) ◽  
pp. 890-894 ◽  
Author(s):  
Bohua Long ◽  
Jingzhao Zhang ◽  
Xueyan Wang ◽  
Xudong Tang ◽  
Zhengzhi Wu
Keyword(s):  
Total Synthesis ◽  
Biological Evaluation ◽  
Synthesis And Biological Evaluation

Total Synthesis and Biological Evaluation of Cortistatins A and J and Analogues Thereof

2009 ◽  
Vol 131 (30) ◽  
pp. 10587-10597 ◽  
Author(s):  
K. C. Nicolaou ◽  
Xiao-Shui Peng ◽  
Ya-Ping Sun ◽  
Damien Polet ◽  
Bin Zou ◽  
...  
Keyword(s):  
Total Synthesis ◽  
Biological Evaluation ◽  
Synthesis And Biological Evaluation

scholarly journals Total Synthesis and Biological Evaluation of the Glycosylated Macrocyclic Antibiotic Mangrolide A

2018 ◽  
Vol 57 (34) ◽  
pp. 11020-11024 ◽  
Author(s):  
Hiromu Hattori ◽  
Joel Roesslein ◽  
Patrick Caspers ◽  
Katja Zerbe ◽  
Hideki Miyatake-Ondozabal ◽  
...  
Keyword(s):  
Total Synthesis ◽  
Biological Evaluation ◽  
Macrocyclic Antibiotic ◽  
Synthesis And Biological Evaluation
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