Catalytic alkylation reactions of weakly acidic carbonyl and related compounds using alkenes as electrophiles

2018 ◽  
Vol 16 (33) ◽  
pp. 5969-5972 ◽  
Author(s):  
Yasuhiro Yamashita ◽  
Ryo Igarashi ◽  
Hirotsugu Suzuki ◽  
Shū Kobayashi
Keyword(s):  
Catalytic Alkylation ◽  
Alkylation Reactions ◽  
Related Compounds

Catalytic alkylation reactions of weakly acidic carbonyl and related pronucleophiles such as amides, esters, and sulfonamides with substituted alkenes have been reported.

Enantio- and Diastereoselective Catalytic Alkylation Reactions with Aziridines

2008 ◽  
Vol 130 (31) ◽  
pp. 10076-10077 ◽  
Author(s):  
Thomas A. Moss ◽  
David R. Fenwick ◽  
Darren J. Dixon
Keyword(s):  
Catalytic Alkylation ◽  
Alkylation Reactions

ChemInform Abstract: Bismuth Salts in Catalytic Alkylation Reactions

ChemInform ◽  
2013 ◽  
Vol 44 (42) ◽  
pp. no-no
Author(s):  
Magnus Rueping ◽  
Boris J. Nachtsheim
Keyword(s):  
Catalytic Alkylation ◽  
Bismuth Salts ◽  
Alkylation Reactions

ChemInform Abstract: Enantio- and Diastereoselective Catalytic Alkylation Reactions with Aziridines.

ChemInform ◽  
2008 ◽  
Vol 39 (50) ◽  
Author(s):  
Thomas A. Moss ◽  
David R. Fenwick ◽  
Darren J. Dixon
Keyword(s):  
Catalytic Alkylation ◽  
Alkylation Reactions

Deciphering the Redox Chain Mechanism in the Catalytic Alkylation of Quinones

Synlett ◽  
2018 ◽  
Vol 29 (14) ◽  
pp. 1807-1813 ◽  
Author(s):  
Zhi Li ◽  
Xiao-Long Xu
Keyword(s):  
Reaction Mechanism ◽  
Lewis Acid ◽  
Kinetic Studies ◽  
Chain Mechanism ◽  
Chain Reaction ◽  
Catalytic Alkylation ◽  
Redox Chain ◽  
Strong Lewis Acid ◽  
Acid Catalyzed ◽  
Alkylation Reactions

Alkylation of p-quinones with allylic and benzylic esters is achieved by using a strong Lewis acid as the catalyst. This transformation likely follows an unusual redox chain mechanism. In this mechanism, quinone undergoes a sequence of reactions: it is reduced to ­hydroquinone (HQ), functionalized in a Lewis acid-catalyzed Friedel–Crafts alkylation, and then oxidized back to quinone. The last step is concurrent with the first step of a second quinone molecule, which is reduced to new HQ and functionalized, and thus propagates the redox chain reaction. The autoinitiation mechanism of the redox chain is not well understood, but additive HQ or Hantzsch ester can serve as effective initiators. The likelihood of this mechanism was elaborated by ­kinetic studies and various control experiments.1 Introduction2 Discovery of Catalytic Alkylation Reactions of Quinones3 Proposed Redox Chain Reaction Mechanism and Experimental Evidence4 Substrate Scope5 Conclusion

Zebrafish models for hallucinogenic-related compounds

2013 ◽  
Author(s):  
A. V. Kalueff ◽  
A. M. Stewart ◽  
V. Gjeloshi ◽  
D. Kondaveeti ◽  
N. Neelkantan ◽  
...  
Keyword(s):  
Related Compounds
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