Recent progress of C-glycosylation methods in the total synthesis of natural products and pharmaceuticals

2018 ◽  
Vol 16 (11) ◽  
pp. 1791-1806 ◽  
Author(s):  
Hongze Liao ◽  
Jimei Ma ◽  
Hui Yao ◽  
Xue-Wei Liu
Keyword(s):  
Natural Products ◽  
Total Synthesis ◽  
Recent Progress

C-Glycosylation has found widespread use in the synthesis of biomedically important natural products and pharmaceuticals.

scholarly journals Non-Enzymatic Desymmetrization Reactions in Aqueous Media

Symmetry ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 720
Author(s):  
Satomi Niwayama
Keyword(s):  
Natural Products ◽  
Total Synthesis ◽  
Functional Groups ◽  
Organic Compounds ◽  
Recent Progress ◽  
Aqueous Media ◽  
Building Blocks ◽  
Organic Reactions ◽  
Environmentally Benign ◽  
Enzymatic Desymmetrization

Symmetric organic compounds are generally obtained inexpensively, and therefore they can be attractive building blocks for the total synthesis of various pharmaceuticals and natural products. The drawback is that discriminating the identical functional groups in the symmetric compounds is difficult. Water is the most environmentally benign and inexpensive solvent. However, successful organic reactions in water are rather limited due to the hydrophobicity of organic compounds in general. Therefore, desymmetrization reactions in aqueous media are expected to offer versatile strategies for the synthesis of a variety of significant organic compounds. This review focuses on the recent progress of desymmetrization reactions of symmetric organic compounds in aqueous media without utilizing enzymes.

Recent progress in the total synthesis of pyrrole-containing natural products (2011-2020)

2021 ◽  
Author(s):  
Nidhi Singh ◽  
Snigdha Singh ◽  
Sahil Kohli ◽  
Aarushi Singh ◽  
Hannah Asiki ◽  
...  
Keyword(s):  
Natural Products ◽  
Drug Discovery ◽  
Total Synthesis ◽  
Chronic Diseases ◽  
Recent Progress ◽  
Structural Complexity

Natural products have long served as a rich resource for drug discovery in the treatment of illnesses and chronic diseases. Among many families exhibiting fascinating structural complexity and impressive bioactivity,...

Recent advances in total syntheses of complex dimeric natural products

2021 ◽  
Author(s):  
Jiawei Sun ◽  
He Yang ◽  
Wenjun Tang
Keyword(s):  
Natural Products ◽  
Total Synthesis ◽  
Recent Progress ◽  
Synthetic Methods ◽  
Total Syntheses ◽  
Recent Advances

This tutorial review describes the recent progress in the total synthesis of dimeric natural products. In particular, effective synthetic methods and bioinspired dimerization strategies are emphasized.

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