Enhanced radiosensitization of ternary Cu3BiSe3 nanoparticles by photo-induced hyperthermia in the second near-infrared biological window

Nanoscale ◽  
2019 ◽  
Vol 11 (15) ◽  
pp. 7157-7165 ◽  
Author(s):  
Jiangfeng Du ◽  
Xin Wang ◽  
Xinghua Dong ◽  
Chenyang Zhang ◽  
Linqiang Mei ◽  
...  
Keyword(s):  
Tumor Metastasis ◽  
Near Infrared ◽  
X Ray ◽  
Induced Hyperthermia ◽  
Inhibit Tumor Metastasis ◽  
High Absorption

PVP-Cu3BiSe3 nanoparticles with strong X-ray attenuation ability and high absorption of NIR-II light could enhance radiothermotherapy and inhibit tumor metastasis.

scholarly journals Bacteria-triggered tumor-specific thrombosis to enable potent photothermal immunotherapy of cancer

2020 ◽  
Vol 6 (33) ◽  
pp. eaba3546 ◽  
Author(s):  
Xuan Yi ◽  
Hailin Zhou ◽  
Yu Chao ◽  
Saisai Xiong ◽  
Jing Zhong ◽  
...  
Keyword(s):  
Immune Responses ◽  
Photothermal Therapy ◽  
Tumor Metastasis ◽  
Near Infrared ◽  
Photoacoustic Imaging ◽  
Immune Checkpoint Blockade ◽  
Immune Memory ◽  
Immunotherapy Of Cancer ◽  
Rapid Clearance ◽  
Inhibit Tumor Metastasis

We discovered that attenuated Salmonella after intravenous injection would proliferate within various types of solid tumors but show rapid clearance in normal organs, without rendering notable toxicity. Bacteria-induced inflammation would trigger thrombosis in the infected tumors by destroying tumor blood vessels. Six types of tested tumors would all turn into darkened color with strong near-infrared absorbance, as observed by photoacoustic imaging. Under laser irradiation, those bacterial-infected tumors would be effectively ablated. Because of the immune-stimulation function, such bacteria-based photothermal therapy (PTT) would subsequently trigger antitumor immune responses, which could be further enhanced by immune checkpoint blockade to effectively suppress the growth of abscopal tumors. A robust immune memory effect to reject rechallenged tumors is also observed after bacteria-based PTT. Our work demonstrates that bacteria by themselves could act as a tumor-specific PTT agent to enable photoimmunotherapy cancer therapy to inhibit tumor metastasis and recurrence.

THE OPTICAL AND NEAR-INFRARED COUNTERPART OF GRS 1758-258

2010 ◽  
Vol 19 (06) ◽  
pp. 757-761
Author(s):  
A. J. MUÑOZ-ARJONILLA ◽  
J. MARTÍ ◽  
J. R. SÁNCHEZ-SUTIL ◽  
E. SÁNCHEZ-AYASO ◽  
P. L. LUQUE-ESCAMILLA ◽  
...  
Keyword(s):  
Near Infrared ◽  
Galactic Center ◽  
Single Source ◽  
X Ray ◽  
Center Region ◽  
Infrared Wavelengths ◽  
Star Catalogs ◽  
High Absorption

GRS 1758-258 is one of the two brightest persistent hard X–ray sources in the Galactic Center region, of which an optical/near infrared counterpart has not been unambiguously identified in previous work, mainly due to high absorption and the lack of suitable astrometric stars in early times. In this work, we take advantage of modern star catalogs to reanalyze archival images of the field in the optical and near infrared wavelengths, and compute a new astrometric solution. As a result, a single source is consistent with radio and X–ray sub-arcsec positions, which we propose as the counterpart of GRS 1758-258.

scholarly journals Theranostic near-infrared-IIb emitting nanoprobes for promoting immunogenic radiotherapy and abscopal effects against cancer metastasis

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Hao Li ◽  
Meng Wang ◽  
Biao Huang ◽  
Su-Wen Zhu ◽  
Jun-Jie Zhou ◽  
...  
Keyword(s):  
Cancer Cells ◽  
Tumor Metastasis ◽  
Therapeutic Strategy ◽  
Cancer Metastasis ◽  
Near Infrared ◽  
Tumor Region ◽  
Poly Ethylene ◽  
Precision Radiotherapy ◽  
Immunosuppressive Cells ◽  
Inhibit Tumor Metastasis

AbstractRadiotherapy is an important therapeutic strategy for cancer treatment through direct damage to cancer cells and augmentation of antitumor immune responses. However, the efficacy of radiotherapy is limited by hypoxia-mediated radioresistance and immunosuppression in tumor microenvironment. Here, we construct a stabilized theranostic nanoprobe based on quantum dots emitting in the near-infrared IIb (NIR-IIb, 1,500–1,700 nm) window modified by catalase, arginine–glycine–aspartate peptides and poly(ethylene glycol). We demonstrate that the nanoprobes effectively aggregate in the tumor site to locate the tumor region, thereby realizing precision radiotherapy with few side-effects. In addition, nanoprobes relieve intratumoral hypoxia and reduce the tumor infiltration of immunosuppressive cells. Moreover, the nanoprobes promote the immunogenic cell death of cancer cells to trigger the activation of dendritic cells and enhance T cell-mediated antitumor immunity to inhibit tumor metastasis. Collectively, the nanoprobe-mediated immunogenic radiotherapy can boost the abscopal effect to inhibit tumor metastasis and prolong survival.

scholarly journals NEAR-INFRARED AND X-RAY QUASI-PERIODIC OSCILLATIONS IN NUMERICAL MODELS OF Sgr A*

2012 ◽  
Vol 746 (1) ◽  
pp. L10 ◽  
Author(s):  
Joshua C. Dolence ◽  
Charles F. Gammie ◽  
Hotaka Shiokawa ◽  
Scott C. Noble
Keyword(s):  
Near Infrared ◽  
Numerical Models ◽  
Periodic Oscillations ◽  
X Ray ◽  
Sgr A

scholarly journals Characterization and mapping of hematite ore mineral classes using hyperspectral remote sensing technique: a case study from Bailadila iron ore mining region

2021 ◽  
Vol 3 (2) ◽  
Author(s):  
Ibrahim Shaik ◽  
S. K. Begum ◽  
P. V. Nagamani ◽  
Narayan Kayet
Keyword(s):  
Infrared Absorption ◽  
Near Infrared ◽  
Spectral Feature ◽  
Absorption Feature ◽  
X Ray ◽  
Remote Sensing Technique ◽  
Ore Minerals ◽  
Feature Fitting ◽  
Hematite Ore

AbstractThe study demonstrates a methodology for mapping various hematite ore classes based on their reflectance and absorption spectra, using Hyperion satellite imagery. Substantial validation is carried out, using the spectral feature fitting technique, with the field spectra measured over the Bailadila hill range in Chhattisgarh State in India. The results of the study showed a good correlation between the concentration of iron oxide with the depth of the near-infrared absorption feature (R2 = 0.843) and the width of the near-infrared absorption feature (R2 = 0.812) through different empirical models, with a root-mean-square error (RMSE) between < 0.317 and < 0.409. The overall accuracy of the study is 88.2% with a Kappa coefficient value of 0.81. Geochemical analysis and X-ray fluorescence (XRF) of field ore samples are performed to ensure different classes of hematite ore minerals. Results showed a high content of Fe > 60 wt% in most of the hematite ore samples, except banded hematite quartzite (BHQ) (< 47 wt%).

scholarly journals Coherence tomography with broad bandwidth extreme ultraviolet and soft X-ray radiation

2021 ◽  
Vol 127 (4) ◽  
Author(s):  
S. Skruszewicz ◽  
S. Fuchs ◽  
J. J. Abel ◽  
J. Nathanael ◽  
J. Reinhard ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Near Infrared ◽  
Extreme Ultraviolet ◽  
Infrared Light ◽  
Imaging Method ◽  
Optical Coherence ◽  
Axial Resolution ◽  
Cross Sectional ◽  
X Ray ◽  
Broad Bandwidth

AbstractWe present an overview of recent results on optical coherence tomography with the use of extreme ultraviolet and soft X-ray radiation (XCT). XCT is a cross-sectional imaging method that has emerged as a derivative of optical coherence tomography (OCT). In contrast to OCT, which typically uses near-infrared light, XCT utilizes broad bandwidth extreme ultraviolet (XUV) and soft X-ray (SXR) radiation (Fuchs et al in Sci Rep 6:20658, 2016). As in OCT, XCT’s axial resolution only scales with the coherence length of the light source. Thus, an axial resolution down to the nanometer range can be achieved. This is an improvement of up to three orders of magnitude in comparison to OCT. XCT measures the reflected spectrum in a common-path interferometric setup to retrieve the axial structure of nanometer-sized samples. The technique has been demonstrated with broad bandwidth XUV/SXR radiation from synchrotron facilities and recently with compact laboratory-based laser-driven sources. Axial resolutions down to 2.2 nm have been achieved experimentally. XCT has potential applications in three-dimensional imaging of silicon-based semiconductors, lithography masks, and layered structures like XUV mirrors and solar cells.

Evaluation of swelling properties and drug release from mechanochemical pre-gelatinized glutinous rice starch matrix tablets by near infrared spectroscopy

2021 ◽  
pp. 096703352098235
Author(s):  
Tomomi Takaku ◽  
Yusuke Hattori ◽  
Tetsuo Sasaki ◽  
Tomoaki Sakamoto ◽  
Makoto Otsuka
Keyword(s):  
Drug Release ◽  
Near Infrared ◽  
Nir Spectroscopy ◽  
Matrix Tablets ◽  
Rice Starch ◽  
Release Time ◽  
Swelling Properties ◽  
X Ray ◽  
Glutinous Rice ◽  
Pharmaceutical Properties

The effect of grinding on the pharmaceutical properties of matrix tablets consisting of ground glutinous rice starch (GRS) and theophylline (TH) was predicted by near infrared (NIR) spectroscopy. Ground GRS samples were prepared by grinding GRS in a planetary ball mill for 0-120 min, measured by X-ray diffractometry (XRD) and NIR, and then evaluated for crystallinity (%XRD) based on XRD profiles. Tablets containing TH (5 w/w%), ground GRS (94 w/w%), and magnesium stearate (1 w/w%) were formed by compression. Gel-forming and drug-release processes of the tablets were measured using a dissolution instrument with X-ray computed tomography (XCT). Swelling ratio (SWE) and mean drug-release time (MDT) were evaluated based on XCT and drug-release profiles, respectively. Calibration models for predicting percent %XRD, MDT, and SWE were constructed based on the NIR of ground GRS using partial least-squares. The results indicated the possibility of controlling the pharmaceutical properties of matrix tablets by altering the pre-gelatinization of GRS based on changes in their NIR spectra during the milling process.

scholarly journals New Approach in the Application of Conjugated Polymers: The Light-Activated Source of Versatile Singlet Oxygen Molecule

Materials ◽  
2021 ◽  
Vol 14 (5) ◽  
pp. 1098
Author(s):  
Agata Blacha-Grzechnik
Keyword(s):  
Conjugated Polymers ◽  
Singlet Oxygen ◽  
Near Infrared ◽  
Photophysical Properties ◽  
Short Review ◽  
The Novel ◽  
New Approach ◽  
Intermolecular Energy ◽  
Intermolecular Energy Transfer ◽  
High Absorption

For many years, the research on conjugated polymers (CPs) has been mainly focused on their application in organic electronics. Recent works, however, show that due to the unique optical and photophysical properties of CPs, such as high absorption in UV–Vis or even near-infrared (NIR) region and efficient intra-/intermolecular energy transfer, which can be relatively easily optimized, CPs can be considered as an effective light-activated source of versatile and highly reactive singlet oxygen for medical or catalytic use. The aim of this short review is to present the novel possibilities that lie dormant in those exceptional polymers with the extended system of π-conjugated bonds.

Small-Angle X-Ray Scattering and Near-Infrared Vibrational Spectroscopy of Water Confined in Aerosol-OT Reverse Micelles

ChemPhysChem ◽  
2008 ◽  
Vol 9 (18) ◽  
pp. 2794-2801 ◽  
Author(s):  
Sangeetha Balakrishnan ◽  
Nadeem Javid ◽  
Hermann Weingärtner ◽  
Roland Winter
Keyword(s):  
Vibrational Spectroscopy ◽  
Small Angle ◽  
Reverse Micelles ◽  
Near Infrared ◽  
X Ray ◽  
Aerosol Ot ◽  
X Ray Scattering ◽  
Ray Scattering
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