Floxuridine-containing nucleic acid nanogels for anticancer drug delivery

Nanoscale ◽  
2018 ◽  
Vol 10 (18) ◽  
pp. 8367-8371 ◽  
Author(s):  
Yuan Ma ◽  
Hongxia Liu ◽  
Quanbing Mou ◽  
Deyue Yan ◽  
Xinyuan Zhu ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Nucleic Acid ◽  
Anticancer Drug ◽  
Drug Delivery Systems ◽  
Drug Loading ◽  
Delivery Systems ◽  
The Self ◽  
Anticancer Drug Delivery ◽  
Dna And Rna ◽  
Loading Ratio

Herein, we report the self-assembled floxuridine-containing DNA and RNA nanogels with a precise drug loading ratio as effective drug delivery systems.

Advances in the use of MOFs for Cancer Diagnosis and Treatment: An Overview

2020 ◽  
Vol 26 (33) ◽  
pp. 4174-4184
Author(s):  
Marina P. Abuçafy ◽  
Bruna L. da Silva ◽  
João A. Oshiro-Junior ◽  
Eloisa B. Manaia ◽  
Bruna G. Chiari-Andréo ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Rational Design ◽  
Gas Adsorption ◽  
Drug Loading ◽  
Drug Carriers ◽  
Delivery Systems ◽  
Academic Community ◽  
Anticancer Drug Delivery ◽  
Diagnostic Agents

Nanoparticles as drug delivery systems and diagnostic agents have gained much attention in recent years, especially for cancer treatment. Nanocarriers improve the therapeutic efficiency and bioavailability of antitumor drugs, besides providing preferential accumulation at the target site. Among different types of nanocarriers for drug delivery assays, metal-organic frameworks (MOFs) have attracted increasing interest in the academic community. MOFs are an emerging class of coordination polymers constructed of metal nodes or clusters and organic linkers that show the capacity to combine a porous structure with high drug loading through distinct kinds of interactions, overcoming the limitations of traditional drug carriers explored up to date. Despite the rational design and synthesis of MOFs, structural aspects and some applications of these materials like gas adsorption have already been comprehensively described in recent years; it is time to demonstrate their potential applications in biomedicine. In this context, MOFs can be used as drug delivery systems and theranostic platforms due to their ability to release drugs and accommodate imaging agents. This review describes the intrinsic characteristics of nanocarriers used in cancer therapy and highlights the latest advances in MOFs as anticancer drug delivery systems and diagnostic agents.

Micro/nanomachines: what is needed for them to become a real force in cancer therapy?

Nanoscale ◽  
2019 ◽  
Vol 11 (14) ◽  
pp. 6519-6532 ◽  
Author(s):  
Lucie Reinišová ◽  
Soňa Hermanová ◽  
Martin Pumera
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Anticancer Drug ◽  
Future Development ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Anticancer Drug Delivery

A biomedical perspective is used to assess micro/nanomotor-based anticancer drug delivery systems with recommendations for their effective future development.

Anticancer Drug Delivery Systems Based on Curcumin Nanostructures: A Review

2020 ◽  
Vol 54 (4) ◽  
pp. 353-360
Author(s):  
Zahra Mirzaie ◽  
Mohammad Barati ◽  
Mohammad Asadi Tokmedash
Keyword(s):  
Drug Delivery ◽  
Anticancer Drug ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Anticancer Drug Delivery

Dendritic chitosan as a magnetic and biocompatible nanocarrier for the simultaneous delivery of doxorubicin and methotrexate to MCF-7 cell line

2017 ◽  
Vol 41 (8) ◽  
pp. 3177-3189 ◽  
Author(s):  
Mahdi Rahimi ◽  
Kazem D. Safa ◽  
Effat Alizadeh ◽  
Roya Salehi
Keyword(s):  
Drug Delivery ◽  
Cell Line ◽  
Anticancer Drug ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Ph Responsive ◽  
Anticancer Drug Delivery ◽  
Line P ◽  
Simultaneous Delivery ◽  
Mcf 7

A novel smart, biocompatible, and pH-responsive magnetic highly branched chitosan was synthesized efficiently for use in dual-anticancer drug delivery systems.

Development of curcumin–cyclodextrin/cellulose nanocrystals complexes: New anticancer drug delivery systems

2016 ◽  
Vol 26 (3) ◽  
pp. 941-945 ◽  
Author(s):  
Gautier M.A. Ndong Ntoutoume ◽  
Robert Granet ◽  
Jean Pierre Mbakidi ◽  
Frédérique Brégier ◽  
David Y. Léger ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Anticancer Drug ◽  
Cellulose Nanocrystals ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Anticancer Drug Delivery

Anticancer drug delivery systems based on noncovalent interactions between carbon nanotubes and linear–dendritic copolymers

Soft Matter ◽  
2011 ◽  
Vol 7 (8) ◽  
pp. 4062 ◽  
Author(s):  
Mohsen Adeli ◽  
Farahman Hakimpoor ◽  
Masoumeh Ashiri ◽  
Roya Kabiri ◽  
Masoumeh Bavadi
Keyword(s):  
Carbon Nanotubes ◽  
Drug Delivery ◽  
Anticancer Drug ◽  
Drug Delivery Systems ◽  
Noncovalent Interactions ◽  
Delivery Systems ◽  
Anticancer Drug Delivery

Nanoparticles and mesenchymal stem cells: a win-win alliance for anticancer drug delivery

RSC Advances ◽  
2016 ◽  
Vol 6 (43) ◽  
pp. 36910-36922 ◽  
Author(s):  
Min Li ◽  
Fangrong Zhang ◽  
Kerong Chen ◽  
Cheng Wang ◽  
Yujie Su ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Cancer Therapy ◽  
Anticancer Drug ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Anticancer Drug Delivery

Schematic illustration of the combination of NPs and MSCs drug delivery systems for cancer therapy.

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