Synthesis of hyaluronic acid or O-carboxymethyl chitosan-stabilized ZnO–ginsenoside Rh2 nanocomposites incorporated with aqueous leaf extract of Dendropanax morbifera Léveille: in vitro studies as potential sunscreen agents

2019 ◽  
Vol 43 (23) ◽  
pp. 9188-9200 ◽  
Author(s):  
Josua Markus ◽  
Ramya Mathiyalagan ◽  
Yeon-Ju Kim ◽  
Yaxi Han ◽  
Zuly Elizabeth Jiménez-Pérez ◽  
...  

Synthesis of Rh2–ZnO nanocomposites stabilized with hyaluronic acid or O-carboxymethyl chitosan.

2015 ◽  
Vol 5 (1) ◽  
pp. 15-18 ◽  
Author(s):  
Bekesho Geleta ◽  
Mebrahtu Eyasu ◽  
Selamu Kebamo ◽  
Asfaw Debella ◽  
Eyasu Makonnen ◽  
...  

Author(s):  
I. O. Salaudeen ◽  
M. O. Olajuwon ◽  
A. B. Ajala ◽  
T. O. Abdulkareem ◽  
S. A. Adeniyi ◽  
...  

This study investigated the synthesis, characterization and in vitro antioxidant activity of silver nanoparticles (AgNPs) using the aqueous leaf extract of Justicia carnea.  The aqueous leaf extract of J. carnea was used as a potential reducing and capping agent. To identify the compounds responsible for the reduction of silver ions, the functional groups present in the plant extract were subjected to FTIR. The in vitro antioxidant activity of synthesized nanoparticles was evaluated in terms of ferric reducing antioxidant potential (FRAP), DPPH (1,1-diphenyl-2-picrylhydrazyl) and ABTS (2,2`-azino-bis (3-ethylbenzothiazoline-6-sulphonic acid) free radicals scavenging assays. The surface plasmon resonance confirmed the formation of AgNPs with maximum absorbance at kmax = 446 nm. FTIR revealed the biological macromolecules of J. carnea leaf extract involved in the synthesis and stabilization of AgNPs. UV-Visible spectrophotometer showed absorbance peak in the range of 436-446 nm. The silver nanoparticles exhibited moderate antioxidant activities compared to standard antioxidants (ascorbic acid and BHT). These results confirmed this protocol as simple, eco-friendly, nontoxic and an alternative for conventional physical and chemical methods. It can be concluded that J. carnea leaf extract can be used effectively in the production of potential antioxidant AgNPs which could be useful in various bio-applications such as cosmetics, food and biomedical industry.


2021 ◽  
pp. 114-125
Author(s):  
Mohammed A. Sulaiman ◽  
Mahmoud S. Jada ◽  
Augustine Elizabeth ◽  
Abubakar Umar Modibbo

The in vitro antioxidant activity and in vivo hepatocurative and nephrocurative potential of Newbouldia laevis aqueous leaf extract (NLALE) was evaluated. The study used 30 male, albino rats (Rattus norvegicus) weighing 180 ± 20 g, of which 25 were intoxicated by oral administration of a single dose of diclofenac (100 mg/kg b. wt.). Animals were treated by oral administration of silymarin (200 mg/kg b. wt.), furosemide (1.5 mg/kg b. wt.) and NLALE (200 mg/kg and 400 mg/kg b. wt.) for seven consecutive days before animals were sacrificed on the 8th day and serum/plasma was analyzed for biochemical markers of hepatotoxicity and nephrotoxicity. Phytochemical screening of NLALE revealed the presence of alkaloids, flavonoids, glycosides, phenols, saponins, steroids and tannins. The extract scavenged DPPH radical, reduced Fe3+ and inhibited TBARs in comparable manner to ascorbic acid in vitro. NLALE also attenuated diclofenac-induced liver and kidney intoxication as indicated by the significantly (p<0.05) reduced levels of serum biomarkers of hepatotoxicity: ALT, AST, bilirubin, but increased total protein levels and nephrotoxicity: urea, creatinine, Na+ and K+. The observed effects are dose dependent as the 400 mg/kg b. wt. appeared to be more potent than the 200 mg/kg b. wt. dose. It may be concluded from this study that Newbouldia laevis leaf has ameliorative effect against diclofenac-induced hepatotoxicity and nephrotoxicity probably through antioxidative mechanism and the curative claim and the folkloric use of the plant in the treatment of liver and kidney diseases have been scientifically validated


2015 ◽  
Vol 3 (1) ◽  
pp. 1-5
Author(s):  
Ganesh Ghimire ◽  
Ranjana Gupta ◽  
Arvind K Keshari

Various concentrations of aqueous leaf extract of Lantana camara L. were assessed against second stage juveniles (J2) of Meloidogyne spp. (Goeldi, 1982) for its nematicidal potency in vitro conditions. Study showed 50% concentration of Lantana camara leaf extract at 48 hrs of incubation period and above showed effective in immobilizing second stage of larvae (J2) of Meloidogyne spp. The standard concentration ‘S’ (100%) of leaf extract was found to be highly nematostatic, 98.66% of nematode were found dead in 48 hrs. Similarly, 57.66% of nematode juveniles were found dead when applied 50% concentration in 48 hrs. Mean number of (J2) dead at 100% concentration for three time period was statistically significant highest at 48 hrs. So far, 50% concentration in 48 hrs and above was appropriate for controlling the root-knot nematode which seems as an alternative to chemical pesticides.


2017 ◽  
Vol 2 (2) ◽  
Author(s):  
Sergey Koryakin ◽  
Elena Isaeva ◽  
Evgeniy Beketov ◽  
Aleksei Solovev ◽  
Liliya Ulyanenko, Vladimir Fedorov ◽  
...  

2013 ◽  
Vol 134 (3) ◽  
pp. 327-332 ◽  
Author(s):  
L.E. Ferreira ◽  
P.M.N. Castro ◽  
A.C.S. Chagas ◽  
S.C. França ◽  
R.O. Beleboni

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