Synthesis and structural characterization of CoxFe3−xC (0 ≤ x ≤ 0.3) magnetic nanoparticles for biomedical applications

2019 ◽  
Vol 43 (8) ◽  
pp. 3536-3544 ◽  
Author(s):  
A. Gangwar ◽  
G. Singh ◽  
S. K. Shaw ◽  
R. K. Mandal ◽  
A. Sharma ◽  
...  
Keyword(s):  
Magnetic Nanoparticles ◽  
Structural Characterization ◽  
Biomedical Applications ◽  
Iron Carbides

The ferrofluids of pure and Co-substituted iron carbides exhibited heating abilities suitable for bioapplications.

Magnetorelaxometry procedures for quantitative imaging and characterization of magnetic nanoparticles in biomedical applications

2015 ◽  
Vol 60 (5) ◽  
Author(s):  
Maik Liebl ◽  
Frank Wiekhorst ◽  
Dietmar Eberbeck ◽  
Patricia Radon ◽  
Dirk Gutkelch ◽  
...  
Keyword(s):  
Magnetic Nanoparticles ◽  
Biomedical Applications ◽  
Colloidal Stability ◽  
Quantitative Imaging ◽  
Local Environment ◽  
Quantitative Information ◽  
Magnetic Drug Targeting ◽  
Spatially Resolved ◽  
Fast Change

AbstractQuantitative knowledge about the spatial distribution and local environment of magnetic nanoparticles (MNPs) inside an organism is essential for guidance and improvement of biomedical applications such as magnetic hyperthermia and magnetic drug targeting. Magnetorelaxometry (MRX) provides such quantitative information by detecting the magnetic response of MNPs following a fast change in the applied magnetic field.In this article, we review our MRX based procedures that enable both the characterization and the quantitative imaging of MNPs in a biomedical environment.MRX characterization supported the selection of an MNP system with colloidal stability and suitable cellular MNP uptake. Spatially resolved MRX, a procedure employing multi-channel MRX measurements allowed forThese MRX based measurement and analysis procedures have substantially supported the development of MNP based biomedical applications.

Synthesis and Characterization of Magnetic Nanoparticles for Biomedical Applications

2015 ◽  
pp. 169-176
Author(s):  
J. R. Piñón-Hernández ◽  
I. G. Becerril-Juárez ◽  
A. Ángeles-Pascual ◽  
R. Pérez ◽  
R. Esparza
Keyword(s):  
Magnetic Nanoparticles ◽  
Biomedical Applications ◽  
Synthesis And Characterization

Synthesis and characterization of electro-explosive magnetic nanoparticles for biomedical applications

2017 ◽  
Author(s):  
O. V. Bakina ◽  
E. A. Glazkova ◽  
N. V. Svarovskaya ◽  
M. I. Lerner ◽  
M. S. Korovin ◽  
...  
Keyword(s):  
Magnetic Nanoparticles ◽  
Biomedical Applications ◽  
Synthesis And Characterization

scholarly journals Immobilization of Protein A on Monodisperse Magnetic Nanoparticles for Biomedical Applications

2019 ◽  
Vol 2019 ◽  
pp. 1-9 ◽  
Author(s):  
Bui Trung Thanh ◽  
Nguyen Van Sau ◽  
Heongkyu Ju ◽  
Mohammed J. K. Bashir ◽  
Hieng Kiat Jun ◽  
...  
Keyword(s):  
Electron Microscopy ◽  
Magnetic Nanoparticles ◽  
Biomedical Applications ◽  
Point Of Care ◽  
High Surface ◽  
Protein A ◽  
Volume Ratio ◽  
Controlled Drug Release ◽  
Disease Diagnosis

We presented synthesis and physical characterization of iron oxide magnetic nanoparticles (Fe3O4) for biomedical applications in the size range of 10-30 nm. Magnetic nanoparticles were synthesized by the coprecipitation method, and the particles’ size was controlled by two different injection methods of sodium hydroxide (NaOH). The synthesized magnetic nanoparticles were then modified by using series of linkers including tetraethyl orthosilicate (TEOS), 3-aminopropyltriethoxysilane (APTES), and glutaraldehyde (GA) to generate the structure of Fe3O4/SiO2/NH2/CHO, which can be used for immobilization of protein A. Additionally, we used transmission electron microscopy (TEM), X-ray powder diffraction (XRD), vibrating-sample magnetometry (VSM), and Fourier-transform infrared spectroscopy (FTIR), for characterization of properties and structure of the nanoparticles. An immobilization of protein A on magnetic nanoparticles was studied with a UV-Vis spectrum (UV-Vis) and fluorescence electron microscopy and Bradford method. Results showed that an XRD spectrum with a peak at (311) corresponded to the standard peak of magnetic nanoparticles. In addition, the magnetic nanoparticles with d≥30 nm have higher saturation magnetizations in comparison with the smaller ones with d≤10 nm. However, the smaller magnetic nanoparticles offered higher efficiency for binding of protein A, due to the high surface/volume ratio. These particles with functional groups on their surface are promising candidates for biomedical applications, e.g., drug delivery, controlled drug release, or disease diagnosis in point-of-care test.

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