Phosphorescent cyclometalated iridium(iii) complexes: synthesis, photophysics, DNA interaction, cellular internalization, and cytotoxic activity

2018 ◽  
Vol 42 (20) ◽  
pp. 16846-16854 ◽  
Author(s):  
Satish S. Bhat ◽  
Vidyanand K. Revankar ◽  
Rahul V. Pinjari ◽  
S. Naveen ◽  
N. K. Lokanath ◽  
...  
Keyword(s):  
Cytotoxic Activity ◽  
Dna Interaction ◽  
Cellular Internalization

Phosphorescent cyclometalated quinoline-appended iridium(iii) complexes undergo rapid cellular internalization and accumulate throughout the cell.

Synthesis, cytotoxic activity and DNA interaction of Pd(II) complexes bearing N′-methyl-3,5-dimethyl-1-thiocarbamoylpyrazole

Polyhedron ◽  
2013 ◽  
Vol 65 ◽  
pp. 214-220 ◽  
Author(s):  
Carolina V. Barra ◽  
Fillipe V. Rocha ◽  
Arnaud Gautier ◽  
Laurent Morel ◽  
Marcela B. Quilles ◽  
...  
Keyword(s):  
Cytotoxic Activity ◽  
Dna Interaction

scholarly journals A ruthenium(II)-trithiacyclononane curcuminate complex: Synthesis, characterization, DNA-interaction, and cytotoxic activity

2017 ◽  
Vol 70 (14) ◽  
pp. 2393-2408 ◽  
Author(s):  
Magda Carvalho Henriques ◽  
Maria Amparo F. Faustino ◽  
Artur M. S. Silva ◽  
Juliana Felgueiras ◽  
Margarida Fardilha ◽  
...  
Keyword(s):  
Cytotoxic Activity ◽  
Dna Interaction

Electrochemical, mechanistic, and DFT studies of amine derived diphosphines containing Ru(ii)–cymene complexes with potent in vitro cytotoxic activity against HeLa and triple-negative breast cancer cells MDA-MB-231

2020 ◽  
Vol 49 (45) ◽  
pp. 16498-16514
Author(s):  
Juliana P. da Silva ◽  
Otávio Fuganti ◽  
M. Gabriela Kramer ◽  
Gianella Facchin ◽  
Lucas E. N. Aquino ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cytotoxic Activity ◽  
Cancer Cells ◽  
Triple Negative Breast Cancer ◽  
Breast Cancer Cells ◽  
Triple Negative ◽  
Dna Interaction ◽  
Dft Studies ◽  
Interaction Studies

Electrochemical/chemical, cytotoxic and DNA interaction studies of P–NR–P containing ruthenium–cymene complexes [RuCl(η6-p-cymene)(P–NR–P)]X.

Surfactant–copper(II) Schiff base complexes: synthesis, structural investigation, DNA interaction, docking studies, and cytotoxic activity

2014 ◽  
Vol 33 (4) ◽  
pp. 877-891 ◽  
Author(s):  
Jagadeesan Lakshmipraba ◽  
Sankaralingam Arunachalam ◽  
Rajadurai Vijay Solomon ◽  
Ponnambalam Venuvanalingam ◽  
Anvarbatcha Riyasdeen ◽  
...  
Keyword(s):  
Schiff Base ◽  
Cytotoxic Activity ◽  
Structural Investigation ◽  
Dna Interaction ◽  
Docking Studies ◽  
Schiff Base Complexes

Quinoxaline-2-carboxamide as a carrier ligand in two new platinum(ii) compounds: Synthesis, crystal structure, cytotoxic activity and DNA interaction

2010 ◽  
Vol 39 (21) ◽  
pp. 5152 ◽  
Author(s):  
Patricia Marqués-Gallego ◽  
M. Amparo Gamiz-Gonzalez ◽  
Francisco R. Fortea-Pérez ◽  
Martin Lutz ◽  
Anthony L. Spek ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Cytotoxic Activity ◽  
Dna Interaction

scholarly journals Differential Cellular Internalization of Anti-CD19 and -CD22 Immunotoxins Results in Different Cytotoxic Activity

2008 ◽  
Vol 68 (15) ◽  
pp. 6300-6305 ◽  
Author(s):  
Xing Du ◽  
Richard Beers ◽  
David J. FitzGerald ◽  
Ira Pastan
Keyword(s):  
Cytotoxic Activity ◽  
Cellular Internalization

Synthesis, DNA Interaction, and Cytotoxic Activity of a Novel Proflavine−Dithiazolidinone Pharmacophore

2007 ◽  
Vol 18 (1) ◽  
pp. 93-100 ◽  
Author(s):  
Ladislav Janovec ◽  
Danica Sabolová ◽  
Mária Kožurková ◽  
Helena Paulíková ◽  
Pavol Kristian ◽  
...  
Keyword(s):  
Cytotoxic Activity ◽  
Dna Interaction

scholarly journals Interstrand DNA covalent binding of two dinuclear Ru(ii) complexes. Influence of the extra ring of the bridging ligand on the DNA interaction and cytotoxic activity

2017 ◽  
Vol 46 (11) ◽  
pp. 3611-3622 ◽  
Author(s):  
Héctor J. Lozano ◽  
Natalia Busto ◽  
Gustavo Espino ◽  
Arancha Carbayo ◽  
José M. Leal ◽  
...  
Keyword(s):  
Cytotoxic Activity ◽  
Covalent Binding ◽  
Dna Interaction ◽  
Bridging Ligand ◽  
Interstrand Crosslinking

The quinones naphthazarin and quinizarin intercalate into DNA whereas their p-cymene di-ruthenium(ii) complexes bind covalently via interstrand crosslinking.

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