Novel triple responsive polybenzimidazole synthesized via amine-ene Michael addition

2018 ◽  
Vol 42 (14) ◽  
pp. 11396-11403 ◽  
Author(s):  
Lilong Gao ◽  
Wenlin Wang ◽  
Bing Yu ◽  
Hailin Cong
Keyword(s):  
Drug Delivery ◽  
Michael Addition ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
First Time

BITO polyesters were synthesized for the first time, which show pH, CD and ROS responsiveness and have great potential as drug delivery systems.

scholarly journals Chronology of Global Success: 20 Years of Prof Vallet-Regí Solving Questions

Pharmaceutics ◽  
2021 ◽  
Vol 13 (12) ◽  
pp. 2179
Author(s):  
Miguel Manzano
Keyword(s):  
Drug Delivery ◽  
Mesoporous Materials ◽  
Biomedical Engineering ◽  
Drug Delivery Systems ◽  
Research Team ◽  
Delivery Systems ◽  
Present Review ◽  
Potential Drug ◽  
The World ◽  
First Time

Twenty years ago, a group of bold scientists led by Prof Vallet-Regí suggested for the first time the use of mesoporous materials as potential drug delivery systems. Without knowing it; these pioneers unleashed the beast of creativity around the world because that original idea has been the inspiration of hundreds of scientific groups for the design of many versatile delivery systems based on mesoporous materials. Because the dream is not the destination, it is the journey, the present review aims to summarise the chain of events that catapulted a small and young research team from the grassroots of academia to the elite of the Biomedical Engineering field.

Techniques For The Preparation of Tissue Samples Containing Injectable Polymer Microcapsules

1985 ◽  
Vol 43 ◽  
pp. 710-711
Author(s):  
G.E. Visscher ◽  
R. L. Robison ◽  
G. J. Argentieri
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Gastrocnemius Muscle ◽  
Degradation Process ◽  
Delivery Systems ◽  
Tissue Reaction ◽  
Electron Microscopic ◽  
Tissue Samples ◽  
Injectable Polymer ◽  
Microscopic Techniques

The use of various bioerodable polymers as drug delivery systems has gained considerable interest in recent years. Among some of the shapes used as delivery systems are films, rods and microcapsules. The work presented here will deal with the techniques we have utilized for the analysis of the tissue reaction to and actual biodegradation of injectable microcapsules. This work has utilized light microscopic (LM), transmission (TEM) and scanning (SEM) electron microscopic techniques. The design of our studies has utilized methodology that would; 1. best characterize the actual degradation process without artifacts introduced by fixation procedures and 2. allow for reproducible results.In our studies, the gastrocnemius muscle of the rat was chosen as the injection site. Prior to the injection of microcapsules the skin above the sites was shaved and tattooed for later recognition and recovery. 1.0 cc syringes were loaded with the desired quantity of microcapsules and the vehicle (0.5% hydroxypropylmethycellulose) drawn up. The syringes were agitated to suspend the microcapsules in the injection vehicle.

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