De novo assembly and comparative transcriptome characterization of Poecilobdella javanica provide insight into blood feeding of medicinal leeches

2018 ◽  
Vol 14 (5) ◽  
pp. 352-361 ◽  
Author(s):  
Zichao Liu ◽  
Yanjie Wang ◽  
Xiangrong Tong ◽  
Yuan Su ◽  
Lijiang Yang ◽  
...  
Keyword(s):  
De Novo Assembly ◽  
De Novo ◽  
Blood Feeding ◽  
Comparative Transcriptome ◽  
Classic Model ◽  
Reconstructive Microsurgery ◽  
Medicinal Leeches ◽  
Insight Into

Leeches (family Hirudinidae) are classic model invertebrates used in diverse clinical treatments, such as reconstructive microsurgery, hypertension, and gangrene treatment.

scholarly journals De Novo Assembly and Characterization of the Xenocatantops brachycerus Transcriptome

2018 ◽  
Vol 19 (2) ◽  
pp. 520 ◽  
Author(s):  
Le Zhao ◽  
Xinmei Zhang ◽  
Zhongying Qiu ◽  
Yuan Huang
Keyword(s):  
De Novo Assembly ◽  
De Novo

scholarly journals De novo assembly and characterization of the root transcriptome of Aegilops variabilis during an interaction with the cereal cyst nematode

BMC Genomics ◽  
2012 ◽  
Vol 13 (1) ◽  
pp. 133 ◽  
Author(s):  
De-Lin Xu ◽  
Hai Long ◽  
Jun-Jun Liang ◽  
Jie Zhang ◽  
Xin Chen ◽  
...  
Keyword(s):  
De Novo Assembly ◽  
De Novo ◽  
Cyst Nematode ◽  
Cereal Cyst Nematode ◽  
Root Transcriptome ◽  
Aegilops Variabilis

scholarly journals De novo assembly and characterization of skin transcriptome using RNAseq in sheep (Ovis aries)

2015 ◽  
Vol 14 (1) ◽  
pp. 1371-1384 ◽  
Author(s):  
Y.J. Yue ◽  
J.B. Liu ◽  
M. Yang ◽  
J.L. Han ◽  
T.T. Guo ◽  
...  
Keyword(s):  
De Novo Assembly ◽  
De Novo ◽  
Ovis Aries

Genomic and Cytogenetic Characterization of a Balanced Translocation Disrupting NUP98

2017 ◽  
Vol 152 (3) ◽  
pp. 117-121
Author(s):  
My Linh Thibodeau ◽  
Michelle Steinraths ◽  
Lindsay Brown ◽  
Zheyuan Zong ◽  
Naomi Shomer ◽  
...  
Keyword(s):  
De Novo Assembly ◽  
De Novo ◽  
Chromosome Rearrangement ◽  
Healthy Woman ◽  
Asian Woman ◽  
Balanced Translocation ◽  
Gene Desert ◽  
Fusion Event ◽  
Translocation Breakpoints

A 41-year-old Asian woman with bilateral renal angiomyolipomas (AML) was incidentally identified to have a balanced translocation, 46,XX,t(11;12)(p15.4;q15). She had no other features or family history to suggest a diagnosis of tuberous sclerosis. Her healthy daughter had the same translocation and no renal AML at the age of 3 years. Whole-genome sequencing was performed on genomic maternal DNA isolated from blood. A targeted de novo assembly was then conducted with ABySS for chromosomes 11 and 12. Sanger sequencing was used to validate the translocation breakpoints. As a result, genomic characterization of chromosomes 11 and 12 revealed that the 11p breakpoint disrupted the NUP98 gene in intron 1, causing a separation of the promoter and transcription start site from the rest of the gene. The translocation breakpoint on chromosome 12q was located in a gene desert. NUP98 has not yet been associated with renal AML pathogenesis, but somatic NUP98 alterations are recurrently implicated in hematological malignancies, most often following a gene fusion event. We also found evidence for complex structural events involving chromosome 12, which appear to disrupt the TDG gene. We identified a TDGP1 partially processed pseudogene at 12p12.1, which adds complexity to the de novo assembly. In conclusion, this is the first report of a germline constitutional structural chromosome rearrangement disrupting NUP98 that occurred in a generally healthy woman with bilateral renal AML.

scholarly journals De Novo Assembly and Characterization of Stress Transcriptome in a Salinity-Tolerant Variety CS52 of Brassica juncea

PLoS ONE ◽  
2015 ◽  
Vol 10 (5) ◽  
pp. e0126783 ◽  
Author(s):  
Rita Sharma ◽  
Manjari Mishra ◽  
Brijesh Gupta ◽  
Chirag Parsania ◽  
Sneh L. Singla-Pareek ◽  
...  
Keyword(s):  
Brassica Juncea ◽  
De Novo Assembly ◽  
De Novo ◽  
Tolerant Variety

scholarly journals Author Correction: De novo assembly of the Platycladus orientalis (L.) Franco transcriptome provides insight into the development and pollination mechanism of female cone based on RNA-Seq data

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Wei Zhou ◽  
Qi Chen ◽  
Xiao-Bing Wang ◽  
Tyler O. Hughes ◽  
Jian-Jun Liu ◽  
...  
Keyword(s):  
De Novo Assembly ◽  
De Novo ◽  
Rna Seq ◽  
Female Cone ◽  
Pollination Mechanism ◽  
Platycladus Orientalis ◽  
Insight Into

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

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