Ferrous-cysteine–phosphotungstate nanoagent with neutral pH fenton reaction activity for enhanced cancer chemodynamic therapy

2019 ◽  
Vol 6 (2) ◽  
pp. 369-374 ◽  
Author(s):  
Peiran Zhao ◽  
Zhongmin Tang ◽  
Xiaoyan Chen ◽  
Ziyu He ◽  
Xinhong He ◽  
...  

Chelating strategy and electron shuttle armed nanoagent for killing cancer cells at both an acidic and neutral pH with high CDT efficiency.

2021 ◽  
Vol 17 (8) ◽  
pp. 1510-1524
Author(s):  
Jian Zhou ◽  
Miao Lei ◽  
Xue-Liang Peng ◽  
Dai-Xu Wei ◽  
Lu-Ke Yan

Fenton reaction, a typical inorganic reaction, is broadly utilized in the field of wastewater treatment. Recently In case of its ability to inhibit the growth of cancer cells, it has been frequently reported in cancer treatment. Using the unique tumor microenvironment in cancer cells, many iron-based nanoparticles have been developed to release iron ions in cancer cells to induce Fenton reaction. In this mini review, we outline several different types of iron-based nanoparticles and several main means to enhance Fenton reaction in cancer cells. Finally, we discussed the advantages and disadvantages of iron-based nanoparticles for cancer therapy, prospected the future development of iron-based nanoparticles. It is believed that iron-based nanoparticles can make certain contribution to the cause of human cancer in the future.


2015 ◽  
Vol 14 (2) ◽  
pp. 473-480 ◽  
Author(s):  
Zongping Wang ◽  
Yizhou Guo ◽  
Zizheng Liu ◽  
Xiaonan Feng ◽  
Yiqun Chen ◽  
...  

During rapid ligand-to-metal charge transfer (LMCT) of the Fe(iii)–catechin complex at near-neutral pH, the species Fe2+ and H2O2 is generated in the presence of oxygen, and formed photo-Fenton reaction to produce ˙OH.


2017 ◽  
Vol 17 (10) ◽  
pp. 7651-7655 ◽  
Author(s):  
Young-Chul Lee ◽  
Hyun Uk Lee ◽  
Seo Yeong Oh ◽  
Sung-Chan Jang ◽  
Soon Chang Lee ◽  
...  

2009 ◽  
Vol 43 (18) ◽  
pp. 6927-6933 ◽  
Author(s):  
Andrew W. Vermilyea ◽  
Bettina M. Voelker
Keyword(s):  

2014 ◽  
Vol 256 ◽  
pp. 448-457 ◽  
Author(s):  
Bianca M. Souza ◽  
Marcia W.C. Dezotti ◽  
Rui A.R. Boaventura ◽  
Vítor J.P. Vilar

Author(s):  
Kazem Naddafi ◽  
Susana Silva Martinez ◽  
Ramin Nabizadeh ◽  
Kamyar Yaghmaeian ◽  
Seyed Jamaleddin Shahtaheri ◽  
...  

Abstract This study represents the first application of Fe–citrate-based photo-Fenton chemistry for the degradation of chlorpyrifos (CPF) spiked into agricultural runoff, and its phytotoxicity assessment. The effects of the initial CPF concentration, time and ratio of Fe–citrate/H2O2 on CPF removal during the photo-Fenton reaction were investigated and modeled with analysis of variance using R software by the response-surface methodology package. According to the stationary point in original units, the optimal condition for 70.00% CPF removal was as follows: CPF = 2.5 mg L−1 (0.0), time = 48.0 min (0.585) and Fe–citrate/H2O2 = 0.075 (0.539). Beside running the system at near-neutral pH, another strength of this study is related to the treatment of agricultural runoff contaminated with CPF with a raceway pond reactor, which has the advantages of simplicity of the facilities and procedures, as well as the possibility of using sunlight more efficiently in the field of applications. Finally, untreated and treated agriculture runoffs were used as irrigation to determine their phytotoxic effects on seed germination of cress (Lepidium sativum). Solar photo-Fenton treatment greatly reduced phytotoxicity of agriculture runoff and showed the highest germination percentage (70%) compared to both raw agricultural runoff (60%) and untreated CPF-spiked runoff (35%).


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