scholarly journals Ultra-high capacity microfluidic trapping of giant vesicles for high-throughput membrane studies

Lab on a Chip ◽  
2019 ◽  
Vol 19 (4) ◽  
pp. 626-633 ◽  
Author(s):  
Naresh Yandrapalli ◽  
Tom Robinson
Keyword(s):  
High Throughput ◽  
High Capacity ◽  
Giant Vesicles ◽  
Microfluidic Platform

A high-capacity microfluidic platform designed to capture tens of thousands of giant vesicles for high-throughput membrane analysis.

A microfluidic platform for the high-throughput study of pathological cardiac hypertrophy

Lab on a Chip ◽  
2017 ◽  
Vol 17 (19) ◽  
pp. 3264-3271 ◽  
Author(s):  
Hesam Parsa ◽  
Bryan Z. Wang ◽  
Gordana Vunjak-Novakovic
Keyword(s):  
Cardiac Hypertrophy ◽  
High Throughput ◽  
Volume Overload ◽  
Microfluidic Platform ◽  
Pathological Cardiac Hypertrophy ◽  
High Throughput Study

Currentin vitromodels fall short in deciphering the mechanisms of cardiac hypertrophy induced by volume overload.

scholarly journals Advances in the Use of Microfluidics to Study Crystallization Fundamentals

2019 ◽  
Vol 10 (1) ◽  
pp. 59-83 ◽  
Author(s):  
Nadine Candoni ◽  
Romain Grossier ◽  
Mehdi Lagaize ◽  
Stéphane Veesler
Keyword(s):  
Phase Diagram ◽  
Diffraction Analysis ◽  
High Throughput ◽  
Concentration Measurement ◽  
Ultraviolet Spectroscopy ◽  
X Ray Diffraction ◽  
Chemical Library ◽  
Microfluidic Platform ◽  
X Ray ◽  
Phase Diagram Determination

This review compares droplet-based microfluidic systems used to study crystallization fundamentals in chemistry and biology. An original high-throughput droplet-based microfluidic platform is presented. It uses nanoliter droplets, generates a chemical library, and directly solubilizes powder, thus economizing both material and time. It is compatible with all solvents without the need for surfactant. Its flexibility permits phase diagram determination and crystallization studies (screening and optimizing experiments) and makes it easy to use for nonspecialists in microfluidics. Moreover, it allows concentration measurement via ultraviolet spectroscopy and solid characterization via X-ray diffraction analysis.

scholarly journals Therapy response testing of breast cancer in a 3D high-throughput perfused microfluidic platform

BMC Cancer ◽  
2017 ◽  
Vol 17 (1) ◽  
Author(s):  
Henriette L. Lanz ◽  
Anthony Saleh ◽  
Bart Kramer ◽  
Junmei Cairns ◽  
Chee Ping Ng ◽  
...  
Keyword(s):  
Breast Cancer ◽  
High Throughput ◽  
Therapy Response ◽  
Microfluidic Platform ◽  
Response Testing

scholarly journals Multi-chamber microfluidic platform for high-precision skin permeation testing

Lab on a Chip ◽  
2017 ◽  
Vol 17 (9) ◽  
pp. 1625-1634 ◽  
Author(s):  
M. Alberti ◽  
Y. Dancik ◽  
G. Sriram ◽  
B. Wu ◽  
Y. L. Teo ◽  
...  
Keyword(s):  
High Precision ◽  
High Throughput ◽  
Skin Permeation ◽  
Toxicity Testing ◽  
Skin Penetration ◽  
Microfluidic Platform

We validated a novel microfluidic permeation array for high-precision and high-throughput skin penetration and toxicity testing or screening of chemicals.

scholarly journals Microfluidics-based selection of red-fluorescent proteins with decreased rates of photobleaching

2015 ◽  
Vol 7 (2) ◽  
pp. 263-273 ◽  
Author(s):  
Kevin M. Dean ◽  
Jennifer L. Lubbeck ◽  
Lloyd M. Davis ◽  
Chola K. Regmi ◽  
Prem P. Chapagain ◽  
...  
Keyword(s):  
High Throughput ◽  
Fluorescent Protein ◽  
Fluorescent Proteins ◽  
Microfluidic Platform ◽  
Red Fluorescent Proteins ◽  
New Variant ◽  
Selection Of

We use a high-throughput microfluidic platform that sorts cells on the basis of fluorescent protein photostability to identify a new variant with improved photon output.

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