scholarly journals A droplet microfluidic platform for efficient enzymatic chromatin digestion enables robust determination of nucleosome positioning

Lab on a Chip ◽  
2018 ◽  
Vol 18 (17) ◽  
pp. 2583-2592 ◽  
Author(s):  
Yi Xu ◽  
Jeong-Heon Lee ◽  
Zhaoyu Li ◽  
Liguo Wang ◽  
Tamas Ordog ◽  
...  
Keyword(s):  
Microfluidic Device ◽  
Nucleosome Positioning ◽  
Microfluidic Platform

A microfluidic device was designed to efficiently fragment chromatin for downstream epigenetic assays.

scholarly journals Interfacial Tension Sensor for Low Dosage Surfactant Detection

2021 ◽  
Vol 5 (1) ◽  
pp. 9
Author(s):  
Piotr Pawliszak ◽  
Bronwyn H. Bradshaw-Hajek ◽  
Christopher Greet ◽  
William Skinner ◽  
David A. Beattie ◽  
...  
Keyword(s):  
Interfacial Tension ◽  
Microfluidic Device ◽  
Profile Analysis ◽  
Simple Method ◽  
Bubble Generation ◽  
Flotation Process ◽  
Line Measurement ◽  
Tension Sensor ◽  
Low Dosage

Currently there are no available methods for in-line measurement of gas-liquid interfacial tension during the flotation process. Microfluidic devices have the potential to be deployed in such settings to allow for a rapid in-line determination of the interfacial tension, and hence provide information on frother concentration. This paper presents the development of a simple method for interfacial tension determination based on a microfluidic device with a flow-focusing geometry. The bubble generation frequency in such a microfluidic device is correlated with the concentration of two flotation frothers (characterized by very different adsorption kinetic behavior). The results are compared with the equilibrium interfacial tension values determined using classical profile analysis tensiometry.

scholarly journals Adenosine Triphosphate Measurement in Deep Sea Using a Microfluidic Device

Micromachines ◽  
2018 ◽  
Vol 9 (8) ◽  
pp. 370 ◽  
Author(s):  
Tatsuhiro Fukuba ◽  
Takuroh Noguchi ◽  
Kei Okamura ◽  
Teruo Fujii
Keyword(s):  
Adenosine Triphosphate ◽  
Microfluidic Device ◽  
Deep Sea ◽  
Temperature Sensor ◽  
Biochemical Parameter ◽  
Underwater Vehicle ◽  
Luciferase Assay ◽  
Bioluminescence Intensity

Total ATP (adenosine triphosphate) concentration is a useful biochemical parameter for detecting microbial biomass or biogeochemical activity anomalies in the natural environment. In this study, we describe the development and evaluation of a new version of in situ ATP analyzer improved for the continuous and quantitative determination of ATP in submarine environments. We integrated a transparent microfluidic device containing a microchannel for cell lysis and a channel for the bioluminescence L–L (luciferin–luciferase) assay with a miniature pumping unit and a photometry module for the measurement of the bioluminescence intensity. A heater and a temperature sensor were also included in the system to maintain an optimal temperature for the L–L reaction. In this study, the analyzer was evaluated in deep sea environments, reaching a depth of 200 m using a remotely operated underwater vehicle. We show that the ATP analyzer successfully operated in the deep-sea environment and accurately quantified total ATP within the concentration lower than 5 × 10−11 M.

scholarly journals Utilization of Microfluidic Device for Determination of Nitrite and Nitrate in Water and Soil Samples

2013 ◽  
Vol 25 (12) ◽  
pp. 6486-6490 ◽  
Author(s):  
N. Laitip ◽  
N. Chomnawang ◽  
N. Youngvises ◽  
W. Threeprom
Keyword(s):  
Microfluidic Device ◽  
Soil Samples ◽  
Water And Soil Samples

scholarly journals Microfluidic on-demand droplet generation, storage, retrieval, and merging for single-cell pairing

Lab on a Chip ◽  
2019 ◽  
Vol 19 (3) ◽  
pp. 493-502 ◽  
Author(s):  
Hesam Babahosseini ◽  
Tom Misteli ◽  
Don L. DeVoe
Keyword(s):  
Single Cell ◽  
Aqueous Phase ◽  
Microfluidic Device ◽  
Droplet Generation ◽  
Microfluidic Platform ◽  
On Demand

A multifunctional microfluidic platform combining on-demand aqueous-phase droplet generation, multi-droplet storage, and controlled merging of droplets selected from a storage library in a single integrated microfluidic device is described.

Determination of nitrite ions in environment analysis with a paper-based microfluidic device

2018 ◽  
Vol 47 (41) ◽  
pp. 14799-14807 ◽  
Author(s):  
Yu-Ci Liu ◽  
Chia-Hui Hsu ◽  
Bing-Jyun Lu ◽  
Peng-Yi Lin ◽  
Mei-Lin Ho
Keyword(s):  
Quantitative Determination ◽  
Microfluidic Device ◽  
Environmental Analysis ◽  
Environment Analysis ◽  
Silver Ink ◽  
Analytical Device

A new microfluidic paper-based analytical device, a (Ag-μPAD)-based chemiresistor composed of silver ink, has been developed for the selective, sensitive, and quantitative determination of nitrite ions in environmental analysis.

Determination of lead in water by combining precolumn adsorption and fluorimetric detection in a microfluidic device

2012 ◽  
Vol 4 (4) ◽  
pp. 989 ◽  
Author(s):  
Ting Wu ◽  
Liyun Zhao ◽  
Djibril Faye ◽  
Jean-Pierre Lefevre ◽  
Jacques Delaire ◽  
...  
Keyword(s):  
Microfluidic Device ◽  
Fluorimetric Detection

A microfluidic device for the batch adsorption of a protein on adsorbent particles

The Analyst ◽  
2017 ◽  
Vol 142 (19) ◽  
pp. 3656-3665 ◽  
Author(s):  
Hoon Suk Rho ◽  
Alexander Thomas Hanke ◽  
Marcel Ottens ◽  
Han Gardeniers
Keyword(s):  
Adsorption Isotherm ◽  
Microfluidic Device ◽  
Batch Adsorption ◽  
Single Experiment ◽  
Microfluidic Platform

A microfluidic platform or “microfluidic batch adsorption device” is presented, which performs two sets of 9 parallel protein incubations with/without adsorbent particles to achieve an adsorption isotherm of a protein in a single experiment.

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