Influence of daily fresh pear consumption on biomarkers of cardiometabolic health in middle-aged/older adults with metabolic syndrome: a randomized controlled trial

2019 ◽  
Vol 10 (2) ◽  
pp. 1062-1072
Author(s):  
Negin Navaei ◽  
Shirin Pourafshar ◽  
Neda S. Akhavan ◽  
Nicole S. Litwin ◽  
Elizabeth M. Foley ◽  
...  
Keyword(s):  
Older Adults ◽  
Metabolic Syndrome ◽  
Randomized Controlled Trial ◽  
Functional Food ◽  
Controlled Trial ◽  
Cardiometabolic Health ◽  
Middle Aged ◽  
Randomized Controlled

Previous research suggests potential for fresh pears as a functional food for promoting cardiometabolic health.

scholarly journals The Aging trial: Design of a randomized controlled trial to increase physical activity in middle-aged and older adults

2020 ◽  
Vol 96 ◽  
pp. 106105
Author(s):  
Manfred Diehl ◽  
Abigail Nehrkorn-Bailey ◽  
Katherine Thompson ◽  
Diana Rodriguez ◽  
Kaigang Li ◽  
...  
Keyword(s):  
Physical Activity ◽  
Older Adults ◽  
Randomized Controlled Trial ◽  
Trial Design ◽  
Controlled Trial ◽  
Middle Aged ◽  
Randomized Controlled

scholarly journals A Social Group-Based Information-Motivation-Behavior Skill Intervention to Promote Acceptability and Adoption of Wearable Activity Trackers Among Middle-Aged and Older Adults: Cluster Randomized Controlled Trial

10.2196/14969 ◽  
2020 ◽  
Vol 8 (4) ◽  
pp. e14969
Author(s):  
Jing Liao ◽  
Hai-Yan Xiao ◽  
Xue-Qi Li ◽  
Shu-Hua Sun ◽  
Shi-Xing Liu ◽  
...  
Keyword(s):  
Older Adults ◽  
Randomized Controlled Trial ◽  
Social Group ◽  
Controlled Trial ◽  
Daily Step ◽  
Middle Aged ◽  
Randomized Controlled ◽  
Activity Trackers ◽  
Wearable Activity Trackers ◽  
Cluster Randomized

Background Wearable activity trackers offer potential to optimize behavior and support self-management. To assist older adults in benefiting from mobile technologies, theory-driven deployment strategies are needed to overcome personal, technological, and sociocontextual barriers in technology adoption. Objective To test the effectiveness of a social group–based strategy to improve the acceptability and adoption of activity trackers by middle-aged and older adults. Methods A cluster randomized controlled trial was conducted among 13 groups of middle-aged and older adults (≥45 years) performing group dancing (ie, square dancing) as a form of exercise in Guangzhou from November 2017 to October 2018. These dancing groups were randomized 1:1 into two arms, and both received wrist-worn activity trackers and instructions at the baseline face-to-face assessment. Based on the Information-Motivation-Behavior Skill framework, the intervention arm was also given a tutorial on the purpose of exercise monitoring (Information), encouraged to participate in exercise and share their exercise records with their dancing peers (Motivation), and were further assisted with the use of the activity tracker (Behavior Skill). We examined two process outcomes: acceptability evaluated by a 14-item questionnaire, and adoption assessed by the uploaded step count data. Intention-to-treat analysis was applied, with the treatment effects estimated by multilevel models. Results All dancing groups were followed up for the postintervention reassessment, with 61/69 (88%) participants of the intervention arm (7 groups) and 56/80 (70%) participants of the control arm (6 groups). Participants’ sociodemographic characteristics (mean age 62 years, retired) and health status were comparable between the two arms, except the intervention arm had fewer female participants and lower cognitive test scores. Our intervention significantly increased the participants’ overall acceptability by 6.8 points (95% CI 2.2-11.4), mainly driven by promoted motivation (adjusted group difference 2.0, 95% CI 0.5-3.6), increased usefulness (adjusted group difference 2.5, 95% CI 0.9-4.1), and better perceived ease of use (adjusted group difference 1.2, 95% CI 0.1-2.4), whereas enjoyment and comfort were not increased (adjusted group difference 0.9, 95% CI –0.4-2.3). Higher adoption was also observed among participants in the intervention arm, who were twice as likely to have valid daily step account data than their controlled counterparts (adjusted incidence relative risk [IRR]=2.0, 95% CI 1.2-3.3). The average daily step counts (7803 vs 5653 steps/day for the intervention and control, respectively) were similar between the two arms (adjusted IRR=1.4, 95% CI 0.7-2.5). Conclusions Our social group–based deployment strategy incorporating information, motivation, and behavior skill components effectively promoted acceptability and adoption of activity trackers among community-dwelling middle-aged and older adults. Future studies are needed to examine the long-term effectiveness and apply this social engagement strategy in other group settings or meeting places. Trial Registration Chinese Clinical Trial Registry ChiCTR-IOC-17013185; https://tinyurl.com/vedwc7h.

scholarly journals A Randomized Controlled Trial of Cognitive Training Using a Visual Speed of Processing Intervention in Middle Aged and Older Adults

PLoS ONE ◽  
2013 ◽  
Vol 8 (5) ◽  
pp. e61624 ◽  
Author(s):  
Fredric D. Wolinsky ◽  
Mark W. Vander Weg ◽  
M. Bryant Howren ◽  
Michael P. Jones ◽  
Megan M. Dotson
Keyword(s):  
Older Adults ◽  
Randomized Controlled Trial ◽  
Cognitive Training ◽  
Controlled Trial ◽  
Speed Of Processing ◽  
Middle Aged ◽  
Randomized Controlled ◽  
Visual Speed

scholarly journals Wolfberry Consumption with a Healthy Dietary Pattern Lowers Oxidative Stress and Improves Carotenoids Status in Middle-Aged and Older Adults: A Randomized Controlled Trial

2021 ◽  
Vol 5 (Supplement_2) ◽  
pp. 79-79
Author(s):  
Darel Wee Kiat Toh ◽  
Wan Yee Lee ◽  
Hanzhang Zhou ◽  
Clarinda Sutanto ◽  
Delia Pei Shan Lee ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Older Adults ◽  
Randomized Controlled Trial ◽  
Dietary Pattern ◽  
Controlled Trial ◽  
Middle Aged ◽  
Randomized Controlled ◽  
Dietary Counselling ◽  
The Impact ◽  
Healthy Dietary Pattern

Abstract Objectives The incorporation of zeaxanthin rich wolfberry (Lycium barbarum) into a healthy dietary pattern may augment its antioxidant effects although evidence evaluating whole fruits is lacking. The objectives of this study are to (1) investigate the impact of dietary counselling, either with or without whole dried wolfberry on oxidative stress status in middle-aged and older Singaporean adults and (2) delineate underlying mechanisms by examining associations with the corresponding changes in carotenoids status. Methods In this 16-week, parallel design randomized controlled trial, 40 subjects (29 F, 11 M; aged 50 to 64 y) received dietary counselling to follow a healthy dietary pattern. Compared to the control group (CG, n = 18), the wolfberry group (WG, n = 22) additionally cooked and consumed 15 g/d whole dried wolfberry with their main meals. Biomarkers of oxidative stress (plasma malondialdehyde (MDA) by thiobarbituric acid reactive substance assay and 8-isoprostanes by ELISA) were measured at baseline and week 16. Plasma and dietary carotenoids analyzed by HPLC and 3-day food records respectively were measured at baseline, week 8 and week 16 while skin carotenoids status (SCS) by resonance Raman spectroscopy was assayed every 4 weeks. Results Plasma 8-isoprostanes showed a time effect (P < 0.05), attributed to the marked decline in the WG only (WG: −19.0 ± 43.6 ng/L; CG: −7.7 ± 38.7 ng/L, mean ± SD) though no effect was observed for MDA. A significant interaction effect (P < 0.001), driven by higher plasma zeaxanthin (WG: +0.08 ± 0.13 nmol/L; CG: −0.03 ± 0.05 nmol/L) and SCS (WG: +4242 ± 4938 a.u.; CG: +1713 ± 5921 a.u.) was observed in the WG with a marked increase evident from week 8 onwards although concentrations of the other plasma carotenoids were maintained. Moreover, the change value for plasma zeaxanthin in the WG was inversely associated with the corresponding changes in plasma 8-isoprostanes (−0.21 (−0.43, 0.00) ng/µmol, regression coefficient (95% CI); P = 0.05). This same association was absent in the CG. Conclusions Consuming wolfberry with a healthy dietary pattern attenuates oxidative stress in middle-aged and older adults and this may be attributed to the rich zeaxanthin content in wolfberry. Funding Sources National University of Singapore Ministry of Education, Singapore Agency for Science, Technology and Research.

scholarly journals Effects of a High-Protein Diet Including Whole Eggs on Muscle Composition and Indices of Cardiometabolic Health and Systemic Inflammation in Older Adults with Overweight or Obesity: A Randomized Controlled Trial

Nutrients ◽  
2018 ◽  
Vol 10 (7) ◽  
pp. 946 ◽  
Author(s):  
Christian Wright ◽  
Jing Zhou ◽  
R. Sayer ◽  
Jung Kim ◽  
Wayne Campbell
Keyword(s):  
Older Adults ◽  
Randomized Controlled Trial ◽  
Systemic Inflammation ◽  
Controlled Trial ◽  
Cardiometabolic Health ◽  
Muscle Composition ◽  
Randomized Controlled ◽  
Age Related ◽  
Over Time ◽  
Overweight Or Obesity

Age-related increases in intermuscular adipose tissue (IMAT) impair muscle quality, decrease functional capacity, and promote several cardiometabolic and inflammatory disorders. Whether these age-related alterations in muscle composition improve by consuming a high-protein (HP) diet with whole eggs are unclear. This parallel-design, randomized-controlled trial assessed the effects of a 12-week eucaloric HP diet with three whole eggs per day (1.4 g protein kg−1 day−1) versus a normal-protein diet void of eggs (NP, 0.8 g protein kg−1 day−1) on muscle composition (IMAT), cardiometabolic health, and systemic inflammation in older adults with overweight or obesity (12 men and 10 women; age 70 ± 5 years, BMI 31.3 ± 3.2 kg/m2, mean ± SD). No changes in muscle composition were observed over time, independent of protein intake. Total body weight was reduced in both groups (−3.3 ± 1.2%) and lean mass was preserved only with the HP diet. LDL concentration and hip circumference decreased only with the NP diet, while MCP-1 and HsCRP concentrations increased over time in both groups. A HP diet with whole eggs promotes lean mass retention with modest weight loss, but does not positively influence muscle composition, cardiometabolic health or systemic inflammation, compared to a NP diet void of eggs.

Protocol for a randomized controlled trial of sitting reduction to improve cardiometabolic health in older adults

2021 ◽  
pp. 106593
Author(s):  
Dori E. Rosenberg ◽  
Mikael Anne Greenwood-Hickman ◽  
Jing Zhou ◽  
Andrea J. Cook ◽  
Kayne D. Mettert ◽  
...  
Keyword(s):  
Older Adults ◽  
Randomized Controlled Trial ◽  
Controlled Trial ◽  
Cardiometabolic Health ◽  
Randomized Controlled
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