The protective effects of selenium-enriched spirulina on the reproductive system of male zebrafish (Danio rerio) exposed to beta-cypermethrin

2018 ◽  
Vol 9 (11) ◽  
pp. 5791-5804 ◽  
Author(s):  
Yi Zhang ◽  
Yuhang Zhou ◽  
Qingyang Tang ◽  
Feng Hu ◽  
Lixue Feng ◽  
...  
Keyword(s):  
Danio Rerio ◽  
Reproductive System ◽  
Protective Effects ◽  
Estrogenic Effects

Beta-cypermethrin (beta-CYP), which is widely used for the control of indoor and field pests, is a highly lipophilic insecticide with environmental estrogenic effects.

Protective effects of phlorotannins against ultraviolet B radiation in zebrafish (Danio rerio)

2011 ◽  
Vol 23 (1) ◽  
pp. 51-e12 ◽  
Author(s):  
Seon-Heui Cha ◽  
Chang-Ik Ko ◽  
Daekyung Kim ◽  
You-Jin Jeon
Keyword(s):  
Danio Rerio ◽  
Ultraviolet B ◽  
Protective Effects ◽  
Ultraviolet B Radiation

scholarly journals Adverse effects of nicotine on endometrium receptivity markers: and protective effect of caffeic acid phenyl ester

2020 ◽  
Author(s):  
AMIN NAMDARI ◽  
FARIDEH MOHAMMADIAN ◽  
Fatemeh KHAJEH ◽  
SOUDABEH KAVOUSIPOUR ◽  
behnoosh miladpour
Keyword(s):  
Protective Effect ◽  
Caffeic Acid ◽  
Stromal Cells ◽  
Reproductive System ◽  
Quantitative Polymerase Chain Reaction ◽  
Protective Effects ◽  
Uterine Receptivity ◽  
Endometrial Stromal Cells ◽  
Genes Expression ◽  
Endometrium Receptivity

Abstract Background nicotine adversely affects the female reproductive system and changes the methylation pattern of some genes in the placenta. In contrast, caffeic acid phenylethyl ester) CAPE (, as a potent antioxidant, has protective effects against the harmful effects of oxygen free radical molecules, methotrexate, and pesticides on the reproductive system. To find the effect of nicotine on the endometrium, we investigated three markers of endometrium receptivity including fibroblast growth factor 2, vascular endothelial growth factors A, and C-X-C motif chemokine ligand 12 and also changes in methylation levels of CXCL-12 gene promoter. In addition, we evaluated the protective effect of CAPE against nicotine. Methods the appropriate treatment dose was selected based on the literature, the endometrial stromal cells were divided into 4 groups, including control, treated with nicotine, CAPE, and nicotine followed by CAPE. Finally, the quantitative polymerase chain reaction and Methylation-Specific PCR were carried out. Results The results showed that treatment of endometrial stromal cells with nicotine (10− 6 µM) for 24 h significantly reduced expression of CXCL-12, FGF, and VEGFA genes. However, a decrease in CXCL-12 expression was not associated with increased methylation levels in the studied promoter region. In contrast, endometrial stromal cells treated with CAPE (4 µg/ml) for 24 h adverse significantly nicotine-induced reduction of CXCL-12, FGF, and VEGFA genes expression. Conclusion Exposure to nicotine has negative effects on uterine receptivity, implantation, and fertility, via reducing the expression of VEGFA, CXCL-12, and FGF2 genes. In contrast, CAPE has a protective effects and improves these genes expression.

Protective effects of melatonin on male fertility preservation and reproductive system

Cryobiology ◽  
2020 ◽  
Vol 95 ◽  
pp. 1-8 ◽  
Author(s):  
Tie-Cheng Sun ◽  
Hui-Ying Li ◽  
Xiao-Yu Li ◽  
Kun Yu ◽  
Shou-Long Deng ◽  
...  
Keyword(s):  
Fertility Preservation ◽  
Reproductive System ◽  
Male Fertility ◽  
Protective Effects

Characterization of bacteriophage pAh-1 and its protective effects on experimental infection of Aeromonas hydrophila in Zebrafish (Danio rerio )

2016 ◽  
Vol 40 (6) ◽  
pp. 841-846 ◽  
Author(s):  
M Easwaran ◽  
S H S Dananjaya ◽  
S C Park ◽  
J Lee ◽  
H-J Shin ◽  
...  
Keyword(s):  
Danio Rerio ◽  
Experimental Infection ◽  
Aeromonas Hydrophila ◽  
Protective Effects

Semicarbazide disturbs the reproductive system of male zebrafish ( Danio rerio ) through the GABAergic system

2017 ◽  
Vol 73 ◽  
pp. 149-157 ◽  
Author(s):  
Miao Yu ◽  
Yongliang Feng ◽  
Xiaona Zhang ◽  
Jun Wang ◽  
Hua Tian ◽  
...  
Keyword(s):  
Danio Rerio ◽  
Reproductive System ◽  
Gabaergic System

Neuro-protective effects of nano-formulated hesperetin in a traumatic brain injury model of Danio rerio

2020 ◽  
pp. 1-8 ◽  
Author(s):  
Pragyan Paramita ◽  
Sai Nivethitha Sethu ◽  
Namasivayam Subhapradha ◽  
Vijayashree Ragavan ◽  
Ramachandran Ilangovan ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Danio Rerio ◽  
Protective Effects ◽  
Traumatic Brain Injury Model ◽  
Injury Model

scholarly journals Oxidative Stress, NF-κB-Mediated Inflammation and Apoptosis in the Testes of Streptozotocin–Induced Diabetic Rats: Combined Protective Effects of Malaysian Propolis and Metformin

Antioxidants ◽  
2019 ◽  
Vol 8 (10) ◽  
pp. 465 ◽  
Author(s):  
Victor Udo Nna ◽  
Ainul Bahiyah Abu Bakar ◽  
Azlina Ahmad ◽  
Chinedum Ogbonnaya Eleazu ◽  
Mahaneem Mohamed
Keyword(s):  
Oxidative Stress ◽  
Nitric Oxide ◽  
Reproductive System ◽  
Diabetic Rats ◽  
Male Reproductive System ◽  
Related Factor ◽  
Mrna Levels ◽  
Nuclear Factor ◽  
Protective Effects ◽  
Protein Levels

Oxidative stress, inflammation and apoptosis are major complications that trigger organ failure in diabetes mellitus (DM), and are proven to adversely affect the male reproductive system. Clinical and experimental studies have demonstrated the promising protective effects of propolis in DM and its associated systemic effects. Herein, we investigated the effect of Malaysian propolis (MP) on testicular oxidative stress, inflammation and apoptosis in diabetic rats. Further, the possibility of a complementary effect of MP with the anti-hyperglycaemic agent, metformin (Met), was studied with the idea of recommending its use in the event that Met alone is unable to contain the negative effects of DM on the male reproductive system in mind. Male Sprague-Dawley rats were either gavaged distilled water (normoglycaemic control and diabetic control groups), MP (diabetic rats on MP), Met (diabetic rats on Met) or MP+Met (diabetic rats on MP+Met), for 4 weeks. MP decreased oxidative stress by up-regulating (p < 0.05) testicular mRNA levels of nuclear factor erythroid 2-related factor 2, superoxide dismutase, catalase and glutathione peroxidase; increasing (p < 0.05) the activities of antioxidant enzymes; and decreasing (p < 0.05) lipid peroxidation in the testes and epididymis of diabetic rats. Further, MP down-regulated (p < 0.05) testicular mRNA and protein levels of pro-inflammatory mediators (nuclear factor kappa B, inducible nitric oxide synthase, tumour necrosis factor-α and interleukin (IL)-1β), decreased (p < 0.05) the nitric oxide level, and increased (p < 0.05) IL-10 mRNA and protein levels. MP also down-regulated (p < 0.05) Bax/Bcl-2, p53, casapase-8, caspase-9 and caspase-3 genes, and increased (p < 0.05) testicular germ cell proliferation. MP’s effects were comparable to Met. However, the best results were achieved following co-administration of MP and Met. Therefore, we concluded that administration of the MP+Met combination better attenuates testicular oxidative stress, inflammation and apoptosis in DM, relative to MP or Met monotherapy, and may improve the fertility of males with DM.

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