Understanding the role of extracts from sea buckthorn seed residues in anti-melanogenesis properties on B16F10 melanoma cells

2018 ◽  
Vol 9 (10) ◽  
pp. 5402-5416 ◽  
Author(s):  
Jiachan Zhang ◽  
Changtao Wang ◽  
Chengtao Wang ◽  
Baoguo Sun ◽  
Cai Qi
Keyword(s):  
Melanoma Cells ◽  
Sea Buckthorn ◽  
Hippophae Rhamnoides ◽  
B16f10 Melanoma ◽  
Hydroalcoholic Extract ◽  
Skin Whitening ◽  
Hippophaë Rhamnoides ◽  
Whitening Agent ◽  
B16f10 Melanoma Cells

The hydroalcoholic extract of sea buckthorn (Hippophae rhamnoides L.) seed residues (HYD-SBSR) is a potential skin whitening agent.

scholarly journals Research on the Sea-Buckthorn (Hippophae rhamnoides L.) Eco-Restoration Value in Avoiding Erosion and Supporting Soil Fixation

2016 ◽  
Vol 73 (2) ◽  
pp. 343
Author(s):  
Carmen Georgeta Dumitrescu (Manole)
Keyword(s):  
Root System ◽  
Sea Buckthorn ◽  
Hippophae Rhamnoides ◽  
Plant Roots ◽  
Hippophaë Rhamnoides ◽  
Supporting Soil ◽  
Real Importance ◽  
Hippophae Rhamnoïdes L ◽  
Root Suckers

This paper approaches an issue of real importance, namely the sea-buckthorn influence on the areas attacked by erosion. We consider that this effect is mainly a result of its extremely developed root system, as well as of the nodosities formation on the roots. The study was conducted over a period of 3 years (2011-2013) in two landslides areas from Prahova and Dambovita counties, from where were collected 5 plants (from each area) in 3 repetitions. Calculating the averages regarding the plant roots depth, but also the number of root suckers and nodosities, can be easily deduced the role of these plants in soil fixation, hence their eco-restoration value.

scholarly journals Activation of Murine Immune Cells upon Co-culture with Plasma-treated B16F10 Melanoma Cells

2019 ◽  
Vol 9 (4) ◽  
pp. 660 ◽  
Author(s):  
Katrin Rödder ◽  
Juliane Moritz ◽  
Vandana Miller ◽  
Klaus-Dieter Weltmann ◽  
Hans-Robert Metelmann ◽  
...  
Keyword(s):  
Tumor Cells ◽  
Immune Cells ◽  
Melanoma Cells ◽  
B16f10 Melanoma ◽  
Migratory Activity ◽  
Erk Phosphorylation ◽  
Extracellular Signal ◽  
B16f10 Melanoma Cells ◽  
Physical Plasma

Recent advances in melanoma therapy increased median survival in patients. However, death rates are still high, motivating the need of novel avenues in melanoma treatment. Cold physical plasma expels a cocktail of reactive species that have been suggested for cancer treatment. High species concentrations can be used to exploit apoptotic redox signaling pathways in tumor cells. Moreover, an immune-stimulatory role of plasma treatment, as well as plasma-killed tumor cells, was recently proposed, but studies using primary immune cells are scarce. To this end, we investigated the role of plasma-treated murine B16F10 melanoma cells in modulating murine immune cells’ activation and marker profile. Melanoma cells exposed to plasma showed reduced metabolic and migratory activity, and an increased release of danger signals (ATP, CXCL1). This led to an altered cytokine profile with interleukin-1β (IL-1β) and CCL4 being significantly increased in plasma-treated mono- and co-cultures with immune cells. In T cells, plasma-treated melanoma cells induced extracellular signal-regulated Kinase (ERK) phosphorylation and increased CD28 expression, suggesting their activation. In monocytes, CD115 expression was elevated as a marker for activation. In summary, here we provide proof of concept that plasma-killed tumor cells are recognized immunologically, and that plasma exerts stimulating effects on immune cells alone.

P047 Role of IL-18 in the melanin synthesis of B16F10 melanoma cells

Cytokine ◽  
2012 ◽  
Vol 59 (3) ◽  
pp. 533-534 ◽  
Author(s):  
I.-J. Yoon ◽  
M. Park ◽  
H.-R. Choi ◽  
H.-S. Kang
Keyword(s):  
Melanoma Cells ◽  
Melanin Synthesis ◽  
B16f10 Melanoma ◽  
B16f10 Melanoma Cells

scholarly journals Effect of a Garcinia gardneriana (Planchon and Triana) Zappi hydroalcoholic extract on melanogenesis in B16F10 melanoma cells

2013 ◽  
Vol 148 (1) ◽  
pp. 199-204 ◽  
Author(s):  
Patrícia Mazureki Campos ◽  
Cíntia Delai da Silva Horinouchi ◽  
Arthur da Silveira Prudente ◽  
Valdir Cechinel-Filho ◽  
Daniela de Almeida Cabrini ◽  
...  
Keyword(s):  
Melanoma Cells ◽  
B16f10 Melanoma ◽  
Hydroalcoholic Extract ◽  
B16f10 Melanoma Cells

Inhibitory Effects of Myelophycus simplex Papenfuss Methanol Extract on Melanogenesis in B16F10 Melanoma Cells

2017 ◽  
Vol 46 (1) ◽  
pp. 34-38
Author(s):  
Hyang Suk Kim ◽  
Ji Min Cheon ◽  
Da Hye Kwon ◽  
Eun Ok Choi ◽  
Min Ju Kim ◽  
...  
Keyword(s):  
Methanol Extract ◽  
Melanoma Cells ◽  
Inhibitory Effects ◽  
B16f10 Melanoma ◽  
B16f10 Melanoma Cells

scholarly journals Effect of Ozone Treatment on the Quality of Sea Buckthorn (Hippophae rhamnoides L.)

Plants ◽  
2021 ◽  
Vol 10 (5) ◽  
pp. 847
Author(s):  
Anita Zapałowska ◽  
Natalia Matłok ◽  
Miłosz Zardzewiały ◽  
Tomasz Piechowiak ◽  
Maciej Balawejder
Keyword(s):  
Mechanical Properties ◽  
Volatile Compounds ◽  
Sea Buckthorn ◽  
Hippophae Rhamnoides ◽  
Ozone Treatment ◽  
Aerobic Bacteria ◽  
Hippophaë Rhamnoides ◽  
Hippophae Rhamnoïdes L ◽  
Ozonation Process

The aim of this research was to show the effect of the ozonation process on the quality of sea buckthorn (Hippophae rhamnoides L.). The quality of the ozonated berries of sea buckthorn was assessed. Prior to and after the ozone treatment, a number of parameters, including the mechanical properties, moisture content, microbial load, content of bioactive compounds, and composition of volatile compounds, were determined. The influence of the ozonation process on the composition of volatile compounds and mechanical properties was demonstrated. The ozonation had negligible impact on the weight and moisture of the samples immediately following the treatment. Significant differences in water content were recorded after 7 days of storage. It was shown that the highest dose of ozone (concentration and process time) amounting to 100 ppm for 30 min significantly reduced the water loss. The microbiological analyses showed the effect of ozone on the total count of aerobic bacteria, yeast, and mold. The applied process conditions resulted in the reduction of the number of aerobic bacteria colonies by 3 log cfu g−1 compared to the control (non-ozonated) sample, whereas the number of yeast and mold colonies decreased by 1 log cfu g−1 after the application of 100 ppm ozone gas for 30 min. As a consequence, ozone treatment enhanced the plant quality and extended plant’s storage life.

scholarly journals Phytochemical Analysis of the Fruits of Sea Buckthorn (Hippophae rhamnoides): Identification of Organic Acid Derivatives

Plants ◽  
2021 ◽  
Vol 10 (5) ◽  
pp. 860
Author(s):  
Yong Hoon Lee ◽  
Hee Joo Jang ◽  
Kun Hee Park ◽  
Seon-Hee Kim ◽  
Jung Kyu Kim ◽  
...  
Keyword(s):  
Organic Acid ◽  
Negative Control ◽  
Nutritional Composition ◽  
Sea Buckthorn ◽  
Hippophae Rhamnoides ◽  
Phytochemical Analysis ◽  
Bioactive Constituents ◽  
Hippophaë Rhamnoides ◽  
The Absolute ◽  
New Compounds

Hippophae rhamnoides L. (Elaeagnaceae), commonly known as “Sea buckthorn” and “Vitamin tree”, is a spiny deciduous shrub whose fruit is known for its nutritional composition, such as vitamin C, and is consumed as a dietary supplement worldwide. As part of our ongoing efforts to identify structurally new and bioactive constituents from natural resources, the phytochemical investigation of the extract of H. rhamnoides fruits led to the isolation of one malate derivative (1), five citrate derivatives (2–6), and one quinate derivative (7). The structures of the isolated compounds were elucidated by analysis of 1D and 2D nuclear magnetic resonance (NMR) spectroscopic data and high-resolution electrospray ionization (HR-ESI) liquid chromatography–mass spectrometry (LC/MS) data. Three of the citrate derivatives were identified as new compounds: (S)-1-butyl-5-methyl citrate (3), (S)-1-butyl-1′-methyl citrate (4), and (S)-1-methyl-1′-butyl citrate (6), which turned out to be isolation artifacts. The absolute configurations of the new compounds were established by quantum chemical electronic circular dichroism (ECD) calculation, which is an informative tool for verifying the absolute configuration of organic acid derivatives. The isolated compounds 1–7 were evaluated for their stimulatory effects on osteogenesis. Compounds 1, 3, 4, 6, and 7 stimulated osteogenic differentiation up to 1.4 fold, compared to the negative control. These findings provide experimental evidence that active compounds 1, 3, 4, 6, and 7 induce the osteogenesis of mesenchymal stem cells and activate bone formation.

Influence of host defenses on the hepatic colonization of B16F10 melanoma cells

1988 ◽  
Vol 6 (2) ◽  
pp. 153-169 ◽  
Author(s):  
E. Barberá-Guillem ◽  
M. L. Cañavate ◽  
I. Lopez De Tejada ◽  
F. Vidal-Vanaclocha
Keyword(s):  
Melanoma Cells ◽  
Host Defenses ◽  
B16f10 Melanoma ◽  
B16f10 Melanoma Cells
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