Gadolinium complexes of diethylenetriamine-N-oxide pentaacetic acid-bisamide: a new class of highly stable MRI contrast agents with a hydration number of 3

2019 ◽  
Vol 48 (5) ◽  
pp. 1693-1699 ◽  
Author(s):  
BeiBei Zhang ◽  
Likun Cheng ◽  
Bing Duan ◽  
Weijun Tang ◽  
Yuan Yuan ◽  
...  

Diethylenetriamine-N-oxide pentaacetic acid-bisamide-based Gd(iii) complexes with 3 coordinated water molecules have been synthesized to achieve high stability and over three times of the relaxivities of commercial MRI contrast agents.

2020 ◽  
Vol 49 (26) ◽  
pp. 8927-8932
Author(s):  
Kehan Xu ◽  
Na Xu ◽  
Beibei Zhang ◽  
Weijun Tang ◽  
Yun Ding ◽  
...  

Macrocyclic gadolinium(iii) complexes with hyphenated-amino-N-oxide (HAO) type ligand structures are designed as efficient magnetic resonance imaging (MRI) contrast agents (CAs) with high relaxivity and stability.


2019 ◽  
Vol 131 (29) ◽  
pp. 9976-9980
Author(s):  
Jia Zhang ◽  
Yue Yuan ◽  
Minling Gao ◽  
Zheng Han ◽  
Chengyan Chu ◽  
...  

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