Palladium(ii) and platinum(ii) saccharinate complexes with bis(diphenylphosphino)methane/ethane: synthesis, S-phase arrest and ROS-mediated apoptosis in human colon cancer cells
Keyword(s):
S Phase
◽
Highly cytotoxic Pd(ii)/Pt(ii) complexes of saccharin with diphosphines cause cell arrest at the S phase and the production of excessive ROS, damaging mitochondria and DNA.
Keyword(s):
Keyword(s):