Palladium(ii) and platinum(ii) saccharinate complexes with bis(diphenylphosphino)methane/ethane: synthesis, S-phase arrest and ROS-mediated apoptosis in human colon cancer cells

2018 ◽  
Vol 47 (33) ◽  
pp. 11397-11410 ◽  
Author(s):  
Ceyda Icsel ◽  
Veysel T. Yilmaz ◽  
Muhittin Aygun ◽  
Buse Cevatemre ◽  
Pinar Alper ◽  
...  

Highly cytotoxic Pd(ii)/Pt(ii) complexes of saccharin with diphosphines cause cell arrest at the S phase and the production of excessive ROS, damaging mitochondria and DNA.

2019 ◽  
Vol 71 (7) ◽  
pp. 1181-1188 ◽  
Author(s):  
Ibrahim Turan ◽  
Selim Demir ◽  
Rezzan Aliyazicioglu ◽  
Kagan Kilinc ◽  
Serap Ozer Yaman ◽  
...  

2004 ◽  
Vol 216 (2) ◽  
pp. 175-181 ◽  
Author(s):  
Ge Li ◽  
Dong-Hee Kim ◽  
Tae-Dong Kim ◽  
Byoung-Jeon Park ◽  
Hae-Duck Park ◽  
...  

2001 ◽  
Vol 120 (5) ◽  
pp. A493-A493
Author(s):  
J HARDWICK ◽  
G VANDENBRINK ◽  
S VANDEVENTER ◽  
M PEPPELENBOSCH

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