NIXANTPHOS: a highly active ligand for palladium catalyzed Buchwald–Hartwig amination of unactivated aryl chlorides

Jianyou Mao; Jiadi Zhang; Shuguang Zhang; Patrick J. Walsh

doi:10.1039/c8dt01852a

NIXANTPHOS: a highly active ligand for palladium catalyzed Buchwald–Hartwig amination of unactivated aryl chlorides

Dalton Transactions ◽

10.1039/c8dt01852a ◽

2018 ◽

Vol 47 (26) ◽

pp. 8690-8696 ◽

Cited By ~ 8

Author(s):

Jianyou Mao ◽

Jiadi Zhang ◽

Shuguang Zhang ◽

Patrick J. Walsh

Keyword(s):

Room Temperature ◽

Aryl Chlorides ◽

Highly Active ◽

Active Ligand ◽

Amination Reaction ◽

Palladium Catalyzed ◽

Parent Ligand

The NIXANTPHOS-based catalyst outperformed the parent ligand Xantphos in Pd catalyzed amination reaction of aryl chlorides at room temperature.

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A Highly Active Catalyst for Palladium-Catalyzed Cross-Coupling Reactions: Room-Temperature Suzuki Couplings and Amination of Unactivated Aryl Chlorides

Journal of the American Chemical Society ◽

10.1021/ja982250+ ◽

1998 ◽

Vol 120 (37) ◽

pp. 9722-9723 ◽

Cited By ~ 633

Author(s):

David W. Old ◽

John P. Wolfe ◽

Stephen L. Buchwald

Keyword(s):

Room Temperature ◽

Active Catalyst ◽

Cross Coupling ◽

Coupling Reactions ◽

Aryl Chlorides ◽

Cross Coupling Reactions ◽

Highly Active ◽

Palladium Catalyzed

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ChemInform Abstract: A Highly Active Catalyst for Palladium-Catalyzed Cross-Coupling Reactions: Room-Temperature Suzuki Couplings and Amination of Unactivated Aryl Chlorides.

ChemInform ◽

10.1002/chin.199905063 ◽

2010 ◽

Vol 30 (5) ◽

pp. no-no

Author(s):

D. W. OLD ◽

J. P. WOLFE ◽

S. L. BUCHWALD

Keyword(s):

Room Temperature ◽

Active Catalyst ◽

Cross Coupling ◽

Coupling Reactions ◽

Aryl Chlorides ◽

Cross Coupling Reactions ◽

Highly Active ◽

Palladium Catalyzed

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Highly active palladium catalysts containing a 1,10-phenanthroline analogue N-heterocyclic carbene for room temperature Suzuki-Miyaura coupling reactions of aryl chlorides with arylboronic acids in aqueous media

Tetrahedron Letters ◽

10.1016/j.tetlet.2016.12.071 ◽

2017 ◽

Vol 58 (8) ◽

pp. 726-731 ◽

Cited By ~ 18

Author(s):

Guiyan Liu ◽

Chengxin Liu ◽

Fangwai Han ◽

Zhongliang Wang ◽

Jianhui Wang

Keyword(s):

Palladium Catalysts ◽

Room Temperature ◽

Aqueous Media ◽

Coupling Reactions ◽

Aryl Chlorides ◽

Arylboronic Acids ◽

Highly Active

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ChemInform Abstract: A P,N-Ligand for Palladium-Catalyzed Ammonia Arylation: Coupling of Deactivated Aryl Chlorides, Chemoselective Arylations, and Room Temperature Reactions.

ChemInform ◽

10.1002/chin.201041064 ◽

2010 ◽

Vol 41 (41) ◽

pp. no-no

Author(s):

Rylan J. Lundgren ◽

Brendan D. Peters ◽

Pamela G. Alsabeh ◽

Mark Stradiotto

Keyword(s):

Room Temperature ◽

Aryl Chlorides ◽

Palladium Catalyzed

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ChemInform Abstract: A Highly Active Catalyst for the Room-Temperature Amination and Suzuki Coupling of Aryl Chlorides.

ChemInform ◽

10.1002/chin.199951098 ◽

2010 ◽

Vol 30 (51) ◽

pp. no-no

Author(s):

John P. Wolfe ◽

Stephen L. Buchwald

Keyword(s):

Room Temperature ◽

Active Catalyst ◽

Suzuki Coupling ◽

Aryl Chlorides ◽

Highly Active

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A P,N-Ligand for Palladium-Catalyzed Ammonia Arylation: Coupling of Deactivated Aryl Chlorides, Chemoselective Arylations, and Room Temperature Reactions

Angewandte Chemie ◽

10.1002/ange.201000526 ◽

2010 ◽

Vol 122 (24) ◽

pp. 4165-4168 ◽

Cited By ~ 77

Author(s):

Rylan J. Lundgren ◽

Brendan D. Peters ◽

Pamela G. Alsabeh ◽

Mark Stradiotto

Keyword(s):

Room Temperature ◽

Aryl Chlorides ◽

Palladium Catalyzed

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A Highly Active Catalyst for the Room-Temperature Amination and Suzuki Coupling of Aryl Chlorides

Angewandte Chemie International Edition ◽

10.1002/(sici)1521-3773(19990816)38:16<2413::aid-anie2413>3.0.co;2-h ◽

1999 ◽

Vol 38 (16) ◽

pp. 2413-2416 ◽

Cited By ~ 444

Author(s):

John P. Wolfe ◽

Stephen L. Buchwald

Keyword(s):

Room Temperature ◽

Active Catalyst ◽

Suzuki Coupling ◽

Aryl Chlorides ◽

Highly Active

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ChemInform Abstract: Highly Active, Well-Defined (Cyclopentadiene)(N-heterocyclic carbene)palladium Chloride Complexes for Room-Temperature SuzukiâMiyaura and BuchwaldâHartwig Cross-Coupling Reactions of Aryl Chlorides and Deboronation Homocoupling of Arylboronic Acids.

ChemInform ◽

10.1002/chin.200949085 ◽

2009 ◽

Vol 40 (49) ◽

Author(s):

Zhong Jin ◽

Su-Xian Guo ◽

Xiao-Peng Gu ◽

Ling-Ling Qiu ◽

Hai-Bing Song ◽

...

Keyword(s):

Room Temperature ◽

Cross Coupling ◽

Palladium Chloride ◽

Coupling Reactions ◽

Chloride Complexes ◽

Aryl Chlorides ◽

Arylboronic Acids ◽

Cross Coupling Reactions ◽

Highly Active ◽

Palladium Chloride Complexes

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Functionalized α-keto stabilized sulfonium ylides as highly active ligand precursors for palladium catalyzed Suzuki–Miyaura cross-couplings

Inorganic Chemistry Communications ◽

10.1016/j.inoche.2014.07.027 ◽

2014 ◽

Vol 47 ◽

pp. 123-127 ◽

Cited By ~ 22

Author(s):

Seyyed Javad Sabounchei ◽

Ali Hashemi

Keyword(s):

Highly Active ◽

Active Ligand ◽

Palladium Catalyzed ◽

Ligand Precursors ◽

Sulfonium Ylides

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Highly Active, Well-Defined (Cyclopentadiene)(N-heterocyclic carbene)palladium Chloride Complexes for Room-Temperature Suzuki-Miyaura and Buchwald-Hartwig Cross-Coupling Reactions of Aryl Chlorides and Deboronation Homocoupling of Arylboronic Acids

Advanced Synthesis & Catalysis ◽

10.1002/adsc.200900098 ◽

2009 ◽

Vol 351 (10) ◽

pp. 1575-1585 ◽

Cited By ~ 73

Author(s):

Zhong Jin ◽

Su-Xian Guo ◽

Xiao-Peng Gu ◽

Ling-Ling Qiu ◽

Hai-Bing Song ◽

...

Keyword(s):

Room Temperature ◽

Cross Coupling ◽

Palladium Chloride ◽

Coupling Reactions ◽

Chloride Complexes ◽

Aryl Chlorides ◽

Arylboronic Acids ◽

Cross Coupling Reactions ◽

Highly Active ◽

Palladium Chloride Complexes

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NIXANTPHOS: a highly active ligand for palladium catalyzed Buchwald–Hartwig amination of unactivated aryl chlorides

A Highly Active Catalyst for Palladium-Catalyzed Cross-Coupling Reactions: Room-Temperature Suzuki Couplings and Amination of Unactivated Aryl Chlorides

ChemInform Abstract: A Highly Active Catalyst for Palladium-Catalyzed Cross-Coupling Reactions: Room-Temperature Suzuki Couplings and Amination of Unactivated Aryl Chlorides.

Highly active palladium catalysts containing a 1,10-phenanthroline analogue N-heterocyclic carbene for room temperature Suzuki-Miyaura coupling reactions of aryl chlorides with arylboronic acids in aqueous media

ChemInform Abstract: A P,N-Ligand for Palladium-Catalyzed Ammonia Arylation: Coupling of Deactivated Aryl Chlorides, Chemoselective Arylations, and Room Temperature Reactions.

ChemInform Abstract: A Highly Active Catalyst for the Room-Temperature Amination and Suzuki Coupling of Aryl Chlorides.

A P,N-Ligand for Palladium-Catalyzed Ammonia Arylation: Coupling of Deactivated Aryl Chlorides, Chemoselective Arylations, and Room Temperature Reactions

A Highly Active Catalyst for the Room-Temperature Amination and Suzuki Coupling of Aryl Chlorides

ChemInform Abstract: Highly Active, Well-Defined (Cyclopentadiene)(N-heterocyclic carbene)palladium Chloride Complexes for Room-Temperature SuzukiâMiyaura and BuchwaldâHartwig Cross-Coupling Reactions of Aryl Chlorides and Deboronation Homocoupling of Arylboronic Acids.

Functionalized α-keto stabilized sulfonium ylides as highly active ligand precursors for palladium catalyzed Suzuki–Miyaura cross-couplings

Highly Active, Well-Defined (Cyclopentadiene)(N-heterocyclic carbene)palladium Chloride Complexes for Room-Temperature Suzuki-Miyaura and Buchwald-Hartwig Cross-Coupling Reactions of Aryl Chlorides and Deboronation Homocoupling of Arylboronic Acids

ChemInform Abstract: Highly Active, Well-Defined (Cyclopentadiene)(N-heterocyclic carbene)palladium Chloride Complexes for Room-Temperature SuzukiâMiyaura and BuchwaldâHartwig Cross-Coupling Reactions of Aryl Chlorides and Deboronation Homocoupling of Arylboronic Acids.