scholarly journals Self-assembly and biological activities of ionic liquid crystals derived from aromatic amino acids

2018 ◽  
Vol 20 (31) ◽  
pp. 20371-20381 ◽  
Author(s):  
Manuel M. Neidhardt ◽  
Katharina Schmitt ◽  
Angelika Baro ◽  
Carmen Schneider ◽  
Ursula Bilitewski ◽  
...  
Keyword(s):  
Amino Acids ◽  
Ionic Liquid ◽  
Biological Activity ◽  
Liquid Crystals ◽  
Amino Acid ◽  
Self Assembly ◽  
Biological Activities ◽  
Aromatic Amino Acids ◽  
Ionic Liquid Crystals

Does the mesomorphic behaviour of l-amino acid-based ILCs correlate with biological activity?

Amino acid/crown ether hybrid materials: how charge affects liquid crystalline self-assembly

Soft Matter ◽  
2017 ◽  
Vol 13 (45) ◽  
pp. 8379-8391 ◽  
Author(s):  
Korinna Bader ◽  
Manuel M. Neidhardt ◽  
Tobias Wöhrle ◽  
Robert Forschner ◽  
Angelika Baro ◽  
...  
Keyword(s):  
Ionic Liquid ◽  
Liquid Crystals ◽  
Amino Acid ◽  
Crown Ether ◽  
Hybrid Materials ◽  
Self Assembly ◽  
Liquid Crystalline ◽  
Ionic Liquid Crystals

Introduction of charge simply converted non-conventional tyrosine/crown ether liquid crystals into ionic liquid crystals under change of mesophase type.

Single Amino Acid Based Self-Assemblies of Cysteine and Methionine

2018 ◽  
Author(s):  
Nidhi Gour ◽  
Bharti Koshti ◽  
Chandra Kanth P. ◽  
Dhruvi Shah ◽  
Vivek Shinh Kshatriya ◽  
...  
Keyword(s):  
Amino Acids ◽  
Amino Acid ◽  
Self Assembly ◽  
Aromatic Amino Acids ◽  
Neutral Condition ◽  
Single Amino Acid ◽  
Binding Assays ◽  
Human Neuroblastoma ◽  
Cytotoxicity Assays ◽  
First Time

We report for the very first time self-assembly of Cysteine and Methionine to discrenible strucutres under neutral condition. To get insights into the structure formation, thioflavin T and Congo red binding assays were done which revealed that aggregates may not have amyloid like characteristics. The nature of interactions which lead to such self-assemblies was purported by coincubating assemblies in urea and mercaptoethanol. Further interaction of aggregates with short amyloidogenic dipeptide diphenylalanine (FF) was assessed. While cysteine aggregates completely disrupted FF fibres, methionine albeit triggered fibrillation. The cytotoxicity assays of cysteine and methionine structures were performed on Human Neuroblastoma IMR-32 cells which suggested that aggregates are not cytotoxic in nature and thus, may not have amyloid like etiology. The results presented in the manuscript are striking, since to the best of our knowledge,this is the first report which demonstrates that even non-aromatic amino acids (cysteine and methionine) can undergo spontaneous self-assembly to form ordered aggregates.

scholarly journals Self‐Assembly of Aminocyclopropenium Salts: En Route to Deltic Ionic Liquid Crystals

2020 ◽  
Vol 59 (26) ◽  
pp. 10557-10565
Author(s):  
Juri Litterscheidt ◽  
Jeffrey S. Bandar ◽  
Max Ebert ◽  
Robert Forschner ◽  
Korinna Bader ◽  
...  
Keyword(s):  
Ionic Liquid ◽  
Liquid Crystals ◽  
Self Assembly ◽  
Ionic Liquid Crystals

scholarly journals Ionic Liquid Crystals: Self-assembly of Imidazolium Salts Containing an L-Glutamic Acid Moiety

2008 ◽  
Vol 37 (5) ◽  
pp. 538-539 ◽  
Author(s):  
Sanami Yazaki ◽  
Yuko Kamikawa ◽  
Masafumi Yoshio ◽  
Atsushi Hamasaki ◽  
Tomohiro Mukai ◽  
...  
Keyword(s):  
Ionic Liquid ◽  
Liquid Crystals ◽  
Glutamic Acid ◽  
Self Assembly ◽  
Imidazolium Salts ◽  
Acid Moiety ◽  
Ionic Liquid Crystals

Ionic Liquid Crystals Derived from Amino Acids

2013 ◽  
Vol 19 (47) ◽  
pp. 16058-16065 ◽  
Author(s):  
Markus Mansueto ◽  
Wolfgang Frey ◽  
Sabine Laschat
Keyword(s):  
Amino Acids ◽  
Ionic Liquid ◽  
Liquid Crystals ◽  
Ionic Liquid Crystals

Single Amino Acid Based Self-Assemblies of Cysteine and Methionine

2018 ◽  
Author(s):  
Nidhi Gour ◽  
Bharti Koshti ◽  
Chandra Kanth P. ◽  
Dhruvi Shah ◽  
Vivek Shinh Kshatriya ◽  
...  
Keyword(s):  
Amino Acids ◽  
Amino Acid ◽  
Self Assembly ◽  
Aromatic Amino Acids ◽  
Neutral Condition ◽  
Single Amino Acid ◽  
Binding Assays ◽  
Human Neuroblastoma ◽  
Cytotoxicity Assays ◽  
First Time

We report for the very first time self-assembly of Cysteine and Methionine to discrenible strucutres under neutral condition. To get insights into the structure formation, thioflavin T and Congo red binding assays were done which revealed that aggregates may not have amyloid like characteristics. The nature of interactions which lead to such self-assemblies was purported by coincubating assemblies in urea and mercaptoethanol. Further interaction of aggregates with short amyloidogenic dipeptide diphenylalanine (FF) was assessed. While cysteine aggregates completely disrupted FF fibres, methionine albeit triggered fibrillation. The cytotoxicity assays of cysteine and methionine structures were performed on Human Neuroblastoma IMR-32 cells which suggested that aggregates are not cytotoxic in nature and thus, may not have amyloid like etiology. The results presented in the manuscript are striking, since to the best of our knowledge,this is the first report which demonstrates that even non-aromatic amino acids (cysteine and methionine) can undergo spontaneous self-assembly to form ordered aggregates.

ChemInform Abstract: Ionic Liquid Crystals Derived from Amino Acids.

ChemInform ◽  
2014 ◽  
Vol 45 (16) ◽  
pp. no-no
Author(s):  
Markus Mansueto ◽  
Wolfgang Frey ◽  
Sabine Laschat
Keyword(s):  
Amino Acids ◽  
Ionic Liquid ◽  
Liquid Crystals ◽  
Ionic Liquid Crystals

scholarly journals Self-Assembly of Supramolecular Complexes of Charged Conjugated Polymers and Imidazolium-Based Ionic Liquid Crystals

Giant ◽  
2021 ◽  
pp. 100088
Author(s):  
Shanju Zhang ◽  
Evan Beach ◽  
Paul T. Anastas ◽  
Lisa D. Pfefferle ◽  
Chinedum O. Osuji
Keyword(s):  
Ionic Liquid ◽  
Liquid Crystals ◽  
Conjugated Polymers ◽  
Self Assembly ◽  
Supramolecular Complexes ◽  
Ionic Liquid Crystals

scholarly journals Single Amino Acid Based Self-Assemblies of Cysteine and Methionine

2018 ◽  
Author(s):  
Nidhi Gour ◽  
Bharti Koshti ◽  
Chandra Kanth P. ◽  
Dhruvi Shah ◽  
Vivek Shinh Kshatriya ◽  
...  
Keyword(s):  
Amino Acids ◽  
Amino Acid ◽  
Self Assembly ◽  
Aromatic Amino Acids ◽  
Neutral Condition ◽  
Single Amino Acid ◽  
First Report ◽  
First Time

We report for the very first time self-assembly of Cysteine and Methionine to discrenible strucutres under neutral condition. The nature of interactions which lead to such self-assemblies was purported by coincubating assemblies in urea and mercaptoethanol. Further interaction of aggregates with short amyloidogenic dipeptide diphenylalanine (FF) was assessed. While cysteine aggregates completely disrupted FF fibres, methionine albeit triggered fibrillation. . The results presented in the manuscript are striking, since to the best of our knowledge,this is the first report which demonstrates that even non-aromatic amino acids (cysteine and methionine) can undergo spontaneous self-assembly to form ordered aggregates.

Self-Assembly of Imidazolium-Based Rodlike Ionic Liquid Crystals: Transition from Lamellar to Micellar Organization

2010 ◽  
Vol 16 (15) ◽  
pp. 4588-4601 ◽  
Author(s):  
Xiaohong Cheng ◽  
Xueqing Bai ◽  
Shan Jing ◽  
Helgard Ebert ◽  
Marko Prehm ◽  
...  
Keyword(s):  
Ionic Liquid ◽  
Liquid Crystals ◽  
Self Assembly ◽  
Ionic Liquid Crystals
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