scholarly journals Correction: Encoding matter with regiospecific 12C/13C isotopic labels

2018 ◽  
Vol 54 (28) ◽  
pp. 3543-3543
Author(s):  
James J. La Clair
Keyword(s):  

Correction for ‘Encoding matter with regiospecific 12C/13C isotopic labels’ by James J. La Clair et al., Chem. Commun., 2018, 54, 2611–2614.

2011 ◽  
Vol 418 (1) ◽  
pp. 1-9 ◽  
Author(s):  
Ping Zhang ◽  
Ying Zhang ◽  
Xiangdong Xue ◽  
Chenjian Wang ◽  
Zhongfu Wang ◽  
...  

2018 ◽  
Vol 54 (21) ◽  
pp. 2611-2614 ◽  
Author(s):  
James J. La Clair

Molecules offer excellent vehicles for encoding messages. This article demonstrates how the regiospecific incorporation of non-natural isotope ratios provides a superb signal for molecular encryption.


Science ◽  
2019 ◽  
Vol 363 (6426) ◽  
pp. 525-528 ◽  
Author(s):  
Jordan A. Hachtel ◽  
Jingsong Huang ◽  
Ilja Popovs ◽  
Santa Jansone-Popova ◽  
Jong K. Keum ◽  
...  

The identification of isotopic labels by conventional macroscopic techniques lacks spatial resolution and requires relatively large quantities of material for measurements. We recorded the vibrational spectra of an α amino acid, l-alanine, with damage-free “aloof” electron energy-loss spectroscopy in a scanning transmission electron microscope to directly resolve carbon-site–specific isotopic labels in real space with nanoscale spatial resolution. An isotopic red shift of 4.8 ± 0.4 milli–electron volts in C–O asymmetric stretching modes was observed for 13C-labeled l-alanine at the carboxylate carbon site, which was confirmed by macroscopic infrared spectroscopy and theoretical calculations. The accurate measurement of this shift opens the door to nondestructive, site-specific, spatially resolved identification of isotopically labeled molecules with the electron microscope.


2014 ◽  
Vol 86 (3) ◽  
pp. 1632-1639 ◽  
Author(s):  
Xiaojing Huang ◽  
Ying-Jr Chen ◽  
Kevin Cho ◽  
Igor Nikolskiy ◽  
Peter A. Crawford ◽  
...  

The Lancet ◽  
1962 ◽  
Vol 280 (7251) ◽  
pp. 317-319 ◽  
Author(s):  
K.A. Porter ◽  
E.H. Cooper
Keyword(s):  

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