Polycyclic heteroaromatic ring construction driven by silver/cobalt co-catalyzed desulfonylative and defluorinative fragment-recombination of enol nonaflates with amidines

2018 ◽  
Vol 54 (90) ◽  
pp. 12722-12725 ◽  
Author(s):  
Ting Xie ◽  
Yao-Wei Zhang ◽  
Li-Li Liu ◽  
Zhi-Liang Shen ◽  
Teck-Peng Loh ◽  
...  
Keyword(s):  
Recombination Reaction ◽  
Heteroaromatic Ring

A novel Ag(i)/Co(ii) co-catalyzed tandem fragmentation and recombination reaction commencing from detachable nonaflates and amidines has been developed.

scholarly journals In Vivo Identification of Intermediate Stages of the DNA Inversion Reaction Catalyzed by the Salmonella Hin Recombinase

Genetics ◽  
1998 ◽  
Vol 149 (4) ◽  
pp. 1649-1663
Author(s):  
Oliver Z Nanassy ◽  
Kelly T Hughes
Keyword(s):  
Amino Acids ◽  
Biochemical Analysis ◽  
Mutational Analysis ◽  
Recombination Reaction ◽  
Recombination Site ◽  
Dna Inversion ◽  
Hin Recombinase ◽  
One Step ◽  
A Site

Abstract The Hin recombinase catalyzes a site-specific recombination reaction that results in the reversible inversion of a 1-kbp segment of the Salmonella chromosome. The DNA inversion reaction catalyzed by the Salmonella Hin recombinase is a dynamic process proceeding through many intermediate stages, requiring multiple DNA sites and the Fis accessory protein. Biochemical analysis of this reaction has identified intermediate steps in the inversion reaction but has not yet revealed the process by which transition from one step to another occurs. Because transition from one reaction step to another proceeds through interactions between specific amino acids, and between amino acids and DNA bases, it is possible to study these transitions through mutational analysis of the proteins involved. We isolated a large number of mutants in the Hin recombinase that failed to carry out the DNA exchange reaction. We generated genetic tools that allowed the assignment of these mutants to specific transition steps in the recombination reaction. This genetic analysis, combined with further biochemical analysis, allowed us to define contributions by specific amino acids to individual steps in the DNA inversion reaction. Evidence is also presented in support of a model that Fis protein enhances the binding of Hin to the hixR recombination site. These studies identified regions within the Hin recombinase involved in specific transition steps of the reaction and provided new insights into the molecular details of the reaction mechanism.

scholarly journals Chromosomal transformation inBacillus subtilisis a non-polar recombination reaction

2016 ◽  
Vol 44 (6) ◽  
pp. 2754-2768 ◽  
Author(s):  
Begoña Carrasco ◽  
Ester Serrano ◽  
Humberto Sánchez ◽  
Claire Wyman ◽  
Juan C. Alonso
Keyword(s):  
Recombination Reaction

Synthesis and antibacterial activity of oxazolidinones containing pyridine substituted with heteroaromatic ring

2004 ◽  
Vol 12 (22) ◽  
pp. 5909-5915 ◽  
Author(s):  
Yeong Woo Jo ◽  
Weon Bin Im ◽  
Jae Keol Rhee ◽  
Mi Ja Shim ◽  
Won Bae Kim ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Heteroaromatic Ring

Quantum chemical and kinetic study of the CCl 2 self-recombination reaction

2017 ◽  
Vol 1121 ◽  
pp. 1-10 ◽  
Author(s):  
Nicolás D. Gómez ◽  
Jorge Codnia ◽  
María L. Azcárate ◽  
Carlos J. Cobos
Keyword(s):  
Kinetic Study ◽  
Quantum Chemical ◽  
Recombination Reaction

scholarly journals Condensed heteroaromatic ring systems. VIII Synthesis of 3-substituted isocoumarins from o-halobenzoic acid derivatives.

1986 ◽  
Vol 34 (7) ◽  
pp. 2754-2759 ◽  
Author(s):  
TAKAO SAKAMOTO ◽  
MASAYUKI AN-NAKA ◽  
YOSHINORI KONDO ◽  
HIROSHI YAMANAKA
Keyword(s):  
Ring Systems ◽  
Heteroaromatic Ring

Spin catalysis of the radical recombination reaction

1995 ◽  
Vol 233 (3) ◽  
pp. 315-318 ◽  
Author(s):  
Anatoly L. Buchachenko ◽  
Lyudmila V. Ruban ◽  
Eugene N. Step ◽  
Nicholas J. Turro
Keyword(s):  
Recombination Reaction ◽  
Radical Recombination

Layered compounds II. Layered cyclophanes containing heteroaromatic ring

1971 ◽  
Vol 12 (29) ◽  
pp. 2791-2794 ◽  
Author(s):  
Shigeyoshi Mizogami ◽  
Tetsuo Otsubo ◽  
Yoshiteru Sakata ◽  
Soichi Misumi
Keyword(s):  
Layered Compounds ◽  
Heteroaromatic Ring
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