Iron-catalyzed synthesis of cyclopropanes by in situ generation and decomposition of electronically diversified diazo compounds

2018 ◽  
Vol 54 (94) ◽  
pp. 13256-13259 ◽  
Author(s):  
Emmanuelle M. D. Allouche ◽  
Afnan Al-Saleh ◽  
André B. Charette
Keyword(s):  
Diazo Compounds ◽  
One Pot ◽  
Modular Synthesis ◽  
Direct Participation ◽  
In Situ Generation

The modular synthesis of a variety of trans 1,2-disubstituted cyclopropanes in a one-pot iron-catalyzed cyclopropanation is described. N-nosylhydrazones are used as diazo precursors, allowing the in situ generation of electron-rich diazo compounds and their direct participation in the reaction.

In situ generation of nitrilium from nitrile ylide and the subsequent Mumm rearrangement: copper-catalyzed synthesis of unsymmetrical diacylglycine esters

2016 ◽  
Vol 14 (45) ◽  
pp. 10723-10732 ◽  
Author(s):  
Jijun Chen ◽  
Ying Shao ◽  
Liang Ma ◽  
Meihua Ma ◽  
Xiaobing Wan
Keyword(s):  
Carboxylic Acid ◽  
Diazo Compounds ◽  
Acid Nitrile ◽  
In Situ Generation

A novel in situ generation of nitrilium from nitrile ylide and the subsequent Mumm rearrangement of carboxylic acid, nitrile, and diazo compounds gave various unsymmetrical diacylglycine esters.

One-pot three-component polymerization for in situ generation of AIE-active poly(tetraarylethene)s using Grignard reagents as building blocks

2020 ◽  
Vol 11 (35) ◽  
pp. 5601-5609
Author(s):  
Zijie Qiu ◽  
Qingqing Gao ◽  
Ting Han ◽  
Xiaolin Liu ◽  
Jacky W. Y. Lam ◽  
...  
Keyword(s):  
Building Blocks ◽  
Grignard Reagents ◽  
One Pot ◽  
Aggregation Induced Emission ◽  
In Situ Generation

A facile polymerization route for in situ generation of polymers with aggregation-induced emission (AIE) characteristics has been developed.

scholarly journals Convergent in situ Generation of Both Transketolase Substrates via Transaminase and Aldolase Reactions for Sequential One‐Pot, Three‐Step Cascade Synthesis of Ketoses

ChemCatChem ◽  
2019 ◽  
Vol 12 (3) ◽  
pp. 812-817 ◽  
Author(s):  
Marion Lorillière ◽  
Christine Guérard‐Hélaine ◽  
Thierry Gefflaut ◽  
Wolf‐Dieter Fessner ◽  
Pere Clapés ◽  
...  
Keyword(s):  
One Pot ◽  
In Situ Generation

scholarly journals One-pot synthesis of epoxides from benzyl alcohols and aldehydes

2018 ◽  
Vol 14 ◽  
pp. 2308-2312 ◽  
Author(s):  
Edwin Alfonzo ◽  
Jesse W L Mendoza ◽  
Aaron B Beeler
Keyword(s):  
One Pot ◽  
Sulfonium Salts ◽  
Benzyl Alcohols ◽  
One Pot Synthesis ◽  
Reaction Proceeds ◽  
In Situ Generation

A one-pot synthesis of epoxides from commercially available benzyl alcohols and aldehydes is described. The reaction proceeds through in situ generation of sulfonium salts from benzyl alcohols and their subsequent deprotonation for use in Corey–Chaykovsky epoxidation of aldehydes. The generality of the method is exemplified by the synthesis of 34 epoxides that were made from an array of electronically and sterically varied alcohols and aldehydes.

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