Catalytic asymmetric synthesis of spirooxindoles: recent developments

2018 ◽  
Vol 54 (50) ◽  
pp. 6607-6621 ◽  
Author(s):  
Guang-Jian Mei ◽  
Feng Shi
Keyword(s):  
Asymmetric Synthesis ◽  
Recent Progress ◽  
Feature Article ◽  
The Past ◽  
Catalytic Asymmetric Synthesis ◽  
Recent Developments ◽  
Catalytic Asymmetric

The past four years have witnessed significant developments in the field of the catalytic asymmetric synthesis of spirooxindoles, and this feature article outlines the recent progress in this area, including the contributions of our group. This article is divided into sections according to the size and type of the generated spiro-ring fused at the C3-position of the oxindole core.

Catalytic asymmetric synthesis of polysubstituted spirocyclopropyl oxindoles: organocatalysis versus transition metal catalysis

2015 ◽  
Vol 2 (7) ◽  
pp. 849-858 ◽  
Author(s):  
Zhong-Yan Cao ◽  
Jian Zhou
Keyword(s):  
Transition Metal ◽  
Asymmetric Synthesis ◽  
Recent Progress ◽  
Transition Metal Catalysis ◽  
Metal Catalysis ◽  
Catalytic Asymmetric Synthesis ◽  
Versus Transition ◽  
Catalytic Asymmetric

Recent progress in catalytic asymmetric synthesis of spirocyclopropyl oxindoles via organocatalysis and transition metal catalysis are summarized and discussed.

Catalytic asymmetric synthesis of tetrahydrocarbazoles

2019 ◽  
Vol 55 (44) ◽  
pp. 6151-6164 ◽  
Author(s):  
Fen Tan ◽  
Hong-Gang Cheng
Keyword(s):  
Reaction Mechanism ◽  
Asymmetric Synthesis ◽  
Feature Article ◽  
Reaction Type ◽  
Catalytic Asymmetric Synthesis ◽  
Recent Advances ◽  
Catalytic Asymmetric

This feature article summarises recent advances in catalytic asymmetric synthesis of THCs, with emphases on reaction type and reaction mechanism.

Recent Advances in the Catalytic Asymmetric Construction of Phosphorus-Substituted Quaternary Carbon Stereocenters

Synthesis ◽  
2017 ◽  
Vol 50 (03) ◽  
pp. 440-469 ◽  
Author(s):  
Long Chen
Keyword(s):  
Asymmetric Synthesis ◽  
Reaction Mechanisms ◽  
Recent Progress ◽  
Biologically Active Compounds ◽  
Biologically Active ◽  
Quaternary Carbon ◽  
Active Compounds ◽  
Catalytic Asymmetric Synthesis ◽  
Stereogenic Centers ◽  
Catalytic Asymmetric

Phosphorus-substituted quaternary carbon stereocenters exist widely in drugs and biologically active compounds. Catalytic asymmetric synthesis of such quaternary carbon stereogenic centers is of significant importance, with four synthetic strategies being established. This review summarizes the recent progress in this field, including the advantages and limitations of each strategy, briefly discusses the reaction mechanisms and challenges, and outlines synthetic opportunities still open.1 Introduction2 Asymmetric Hydrophosphonylation3 Asymmetric Electrophilic Phosphination4 Asymmetric Functionalization of P-Substituted Methine Compounds5 Asymmetric Addition to α-Keto- or α-Ketiminophosphonates6 Conclusion

Catalytic enantioselective synthesis of α-chiral azides

2018 ◽  
Vol 5 (9) ◽  
pp. 1542-1559 ◽  
Author(s):  
Pei-Gang Ding ◽  
Xiao-Si Hu ◽  
Feng Zhou ◽  
Jian Zhou
Keyword(s):  
Asymmetric Synthesis ◽  
Recent Progress ◽  
Research Area ◽  
Enantioselective Synthesis ◽  
Future Research ◽  
Current Interest ◽  
Catalytic Asymmetric Synthesis ◽  
Catalytic Asymmetric

The catalytic asymmetric synthesis of α-chiral azides is of current interest and three synthetic strategies have been developed. This review summarizes the recent progress in this research area, discusses the advantages and limitations of each strategy, and outlines synthetic opportunities for future research.

Novel strategies for catalytic asymmetric synthesis of C1-chiral 1,2,3,4-tetrahydroisoquinolines and 3,4-dihydrotetrahydroisoquinolines

2015 ◽  
Vol 2 (3) ◽  
pp. 288-299 ◽  
Author(s):  
Wangsheng Liu ◽  
Shasha Liu ◽  
Ruiwen Jin ◽  
Hao Guo ◽  
Jinbo Zhao
Keyword(s):  
Asymmetric Synthesis ◽  
Recent Progress ◽  
Catalytic Asymmetric Synthesis ◽  
Catalytic Asymmetric ◽  
Privileged Scaffolds

This review summarizes recent progress in catalytic asymmetric construction of 1,2,3,4-tetrahydroisoquinolines and 3,4-dihydroisoquinolines, among the most important “privileged scaffolds”.

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