A self-assembled DNA-nanoparticle with a targeting peptide for hypoxia-inducible gene therapy of ischemic stroke

2019 ◽  
Vol 7 (5) ◽  
pp. 2174-2190 ◽  
Author(s):  
Jungju Oh ◽  
Jaewon Lee ◽  
Chunxian Piao ◽  
Ji Hoon Jeong ◽  
Minhyung Lee
Keyword(s):  
Gene Therapy ◽  
Ischemic Stroke ◽  
Heme Oxygenase ◽  
Heme Oxygenase 1 ◽  
Stroke Therapy ◽  
Self Assembled ◽  
Targeting Peptide ◽  
Inducible Gene

A self-assembled nanoparticle composed of hypoxia-specific anti-RAGE peptide (HSAP), heme oxygenase-1 plasmid (pHO1), and deoxycholate-conjugated polyethylenimine-2k (DP2k) was developed for ischemic stroke therapy.

Heme oxygenase-1 gene therapy: a novel immunomodulatory approach in liver allograft recipients?

2001 ◽  
Vol 33 (1-2) ◽  
pp. 581-582 ◽  
Author(s):  
B Ke ◽  
X.D Shen ◽  
J Melinek ◽  
F Gao ◽  
T Ritter ◽  
...  
Keyword(s):  
Gene Therapy ◽  
Heme Oxygenase ◽  
Heme Oxygenase 1 ◽  
Liver Allograft

Heme Oxygenase -1 Gene Therapy: Recent Advances and Therapeutic Applications

2007 ◽  
Vol 7 (2) ◽  
pp. 89-108 ◽  
Author(s):  
Nader Abraham ◽  
Amit Asija ◽  
George Drummond ◽  
Stephen Peterson
Keyword(s):  
Gene Therapy ◽  
Heme Oxygenase ◽  
Heme Oxygenase 1 ◽  
Therapeutic Applications ◽  
Recent Advances

scholarly journals HEME OXYGENASE-1 GENE THERAPY UPREGULATES TH2-DEPENDENT EXPRESSION OF PROTECTIVE MOLECULES IN LIVER ALLOGRAFT RECIPENTS: IMPLICATIONS FOR NOVEL IMMUNOMODULATORY APPROACH.

2000 ◽  
Vol 69 (Supplement) ◽  
pp. S280
Author(s):  
Bibo Ke ◽  
Xiu-Da Shen ◽  
Judy Melinek ◽  
Ronald W. Busuttil ◽  
Jerzy W. Kupiec-Weglinski
Keyword(s):  
Gene Therapy ◽  
Heme Oxygenase ◽  
Heme Oxygenase 1 ◽  
Liver Allograft

scholarly journals Shorter GT repeat polymorphism in the heme oxygenase-1 gene promoter has protective effect on ischemic stroke in dyslipidemia patients

2010 ◽  
Vol 17 (1) ◽  
pp. 12 ◽  
Author(s):  
Chyi-Huey Bai ◽  
Jiunn-Rong Chen ◽  
Hou-Chang Chiu ◽  
Chia-Chi Chou ◽  
Lee-Young Chau ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Protective Effect ◽  
Heme Oxygenase ◽  
Gene Promoter ◽  
Heme Oxygenase 1 ◽  
Repeat Polymorphism

scholarly journals Heme Oxygenase-1 Gene Therapy Provides Cardioprotection Via Control of Post-Ischemic Inflammation

2015 ◽  
Vol 66 (2) ◽  
pp. 154-165 ◽  
Author(s):  
Rabea Hinkel ◽  
Philipp Lange ◽  
Björn Petersen ◽  
Elena Gottlieb ◽  
Judy King Man Ng ◽  
...  
Keyword(s):  
Gene Therapy ◽  
Heme Oxygenase ◽  
Heme Oxygenase 1

Gene therapy for nucleus pulposus regeneration by heme oxygenase-1 plasmid DNA carried by mixed polyplex micelles with thermo-responsive heterogeneous coronas

Biomaterials ◽  
2015 ◽  
Vol 52 ◽  
pp. 1-13 ◽  
Author(s):  
Ganjun Feng ◽  
Hongying Chen ◽  
Junjie Li ◽  
Qiang Huang ◽  
Melanie J. Gupte ◽  
...  
Keyword(s):  
Gene Therapy ◽  
Nucleus Pulposus ◽  
Heme Oxygenase ◽  
Plasmid Dna ◽  
Heme Oxygenase 1
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