Recent advances in toner-based microfluidic devices for bioanalytical applications

2018 ◽  
Vol 10 (25) ◽  
pp. 2952-2962 ◽  
Author(s):  
Ellen F. M. Gabriel ◽  
Bruno G. Lucca ◽  
Gabriela R. M. Duarte ◽  
Wendell K. T. Coltro

Toner-based microfluidic devices have emerged as promising platforms for bioanalytical applications.

Micromachines ◽  
2019 ◽  
Vol 10 (11) ◽  
pp. 744 ◽  
Author(s):  
Xiangchun Xuan

Magnetic field-induced particle manipulation is simple and economic as compared to other techniques (e.g., electric, acoustic, and optical) for lab-on-a-chip applications. However, traditional magnetic controls require the particles to be manipulated being magnetizable, which renders it necessary to magnetically label particles that are almost exclusively diamagnetic in nature. In the past decade, magnetic fluids including paramagnetic solutions and ferrofluids have been increasingly used in microfluidic devices to implement label-free manipulations of various types of particles (both synthetic and biological). We review herein the recent advances in this field with focus upon the continuous-flow particle manipulations. Specifically, we review the reported studies on the negative magnetophoresis-induced deflection, focusing, enrichment, separation, and medium exchange of diamagnetic particles in the continuous flow of magnetic fluids through microchannels.


RSC Advances ◽  
2016 ◽  
Vol 6 (93) ◽  
pp. 90666-90673 ◽  
Author(s):  
Elias Mechref ◽  
Jihane Jabbour ◽  
Sylvie Calas-Etienne ◽  
Kassem Amro ◽  
Ahmad Mehdi ◽  
...  

Miniaturized total analysis systems are becoming a powerful tool for analytical and bioanalytical applications.


TECHNOLOGY ◽  
2017 ◽  
Vol 05 (01) ◽  
pp. 1-12 ◽  
Author(s):  
Aslihan Gokaltun ◽  
Martin L. Yarmush ◽  
Ayse Asatekin ◽  
O. Berk Usta

In the last decade microfabrication processes including rapid prototyping techniques have advanced rapidly and achieved a fairly mature stage. These advances have encouraged and enabled the use of microfluidic devices by a wider range of users with applications in biological separations and cell and organoid cultures. Accordingly, a significant current challenge in the field is controlling biomolecular interactions at interfaces and the development of novel biomaterials to satisfy the unique needs of the biomedical applications. Poly(dimethylsiloxane) (PDMS) is one of the most widely used materials in the fabrication of microfluidic devices. The popularity of this material is the result of its low cost, simple fabrication allowing rapid prototyping, high optical transparency, and gas permeability. However, a major drawback of PDMS is its hydrophobicity and fast hydrophobic recovery after surface hydrophilization. This results in significant nonspecific adsorption of proteins as well as small hydrophobic molecules such as therapeutic drugs limiting the utility of PDMS in biomedical microfluidic circuitry. Accordingly, here, we focus on recent advances in surface molecular treatments to prevent fouling of PDMS surfaces towards improving its utility and expanding its use cases in biomedical applications.


2017 ◽  
Vol 11 (6) ◽  
pp. 1470-1477 ◽  
Author(s):  
Richard Piffer Soares de Campos ◽  
Camila Dalben Madeira Campos ◽  
Gabriela Brito Almeida ◽  
Jose Alberto Fracassi da Silva

Author(s):  
Yuehe Lin ◽  
Dean W. Matson ◽  
Dean E. Kurath ◽  
Jenny Wen ◽  
Fan Xiang ◽  
...  

2001 ◽  
pp. 103-112 ◽  
Author(s):  
C. Provin ◽  
S. Monneret ◽  
H. Le Gall ◽  
H. Rigneault ◽  
P.-F. Lenne ◽  
...  

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