Aptameric detection of quinine in reclaimed wastewater using a personal glucose meter

2018 ◽  
Vol 10 (24) ◽  
pp. 2931-2938 ◽  
Author(s):  
Yong Qiu ◽  
Chunmei Gu ◽  
Bing Li ◽  
Hanchang Shi
Keyword(s):  
Human Resources ◽  
Small Molecule ◽  
Aqueous Environment ◽  
Reclaimed Wastewater ◽  
Personal Glucose Meter ◽  
Glucose Meter

Quantification of small-molecule analytes in an aqueous environment remains expensive due to the high costs of instruments and human resources.

scholarly journals Personal Glucose Meter for α-Glucosidase Inhibitor Screening Based on the Hydrolysis of Maltose

Molecules ◽  
2021 ◽  
Vol 26 (15) ◽  
pp. 4638
Author(s):  
Tao Tian ◽  
Guo-Ying Chen ◽  
Hao Zhang ◽  
Feng-Qing Yang
Keyword(s):  
Blood Glucose ◽  
Small Molecule ◽  
Inhibitory Activity ◽  
Direct Determination ◽  
Postprandial Blood Glucose ◽  
Experimental Conditions ◽  
Glucosidase Inhibitor ◽  
Personal Glucose Meter ◽  
Glucose Meter ◽  
Hydrolysis Of

As a key enzyme regulating postprandial blood glucose, α-Glucosidase is considered to be an effective target for the treatment of diabetes mellitus. In this study, a simple, rapid, and effective method for enzyme inhibitors screening assay was established based on α-glucosidase catalyzes reactions in a personal glucose meter (PGM). α-glucosidase catalyzes the hydrolysis of maltose to produce glucose, which triggers the reduction of ferricyanide (K3[Fe(CN)6]) to ferrocyanide (K4[Fe(CN)6]) and generates the PGM detectable signals. When the α-glucosidase inhibitor (such as acarbose) is added, the yield of glucose and the readout of PGM decreased accordingly. This method can achieve the direct determination of α-glucosidase activity by the PGM as simple as the blood glucose tests. Under the optimal experimental conditions, the developed method was applied to evaluate the inhibitory activity of thirty-four small-molecule compounds and eighteen medicinal plants extracts on α-glucosidase. The results exhibit that lithospermic acid (52.5 ± 3.0%) and protocatechualdehyde (36.8 ± 2.8%) have higher inhibitory activity than that of positive control acarbose (31.5 ± 2.5%) at the same final concentration of 5.0 mM. Besides, the lemon extract has a good inhibitory effect on α-glucosidase with a percentage of inhibition of 43.3 ± 3.5%. Finally, the binding sites and modes of four active small-molecule compounds to α-glucosidase were investigated by molecular docking analysis. These results indicate that the PGM method is feasible to screening inhibitors from natural products with simple and rapid operations.

scholarly journals Correction to “DNAzyme Amplified Aptasensing Platform for Ochratoxin A Detection Using a Personal Glucose Meter”

2021 ◽  
Author(s):  
Songbai Zhang ◽  
Yunxia Luan ◽  
Mengyi Xiong ◽  
Jingjing Zhang ◽  
Ryan Lake ◽  
...  
Keyword(s):  
Ochratoxin A ◽  
Personal Glucose Meter ◽  
Glucose Meter

Bioinspired DNA–Inorganic Hybrid Nanoflowers Combined with a Personal Glucose Meter for Onsite Detection of miRNA

2018 ◽  
Vol 10 (49) ◽  
pp. 42050-42057 ◽  
Author(s):  
Tingting Wu ◽  
Yuemeng Yang ◽  
Yu Cao ◽  
Yongchao Song ◽  
Li-Ping Xu ◽  
...  
Keyword(s):  
Inorganic Hybrid ◽  
Personal Glucose Meter ◽  
Glucose Meter

A Personal Glucose Meter for Label-Free and Washing-Free Biomolecular Detection

2018 ◽  
Vol 90 (19) ◽  
pp. 11340-11343 ◽  
Author(s):  
Jun Ki Ahn ◽  
Hyo Yong Kim ◽  
Ki Soo Park ◽  
Hyun Gyu Park
Keyword(s):  
Label Free ◽  
Biomolecular Detection ◽  
Personal Glucose Meter ◽  
Glucose Meter

The use of a personal glucose meter for detecting procalcitonin through glucose encapsulated within liposomes

The Analyst ◽  
2019 ◽  
Vol 144 (21) ◽  
pp. 6225-6230 ◽  
Author(s):  
Fida'a Alshawawreh ◽  
Fabio Lisi ◽  
Nicholas Ariotti ◽  
Padmavathy Bakthavathsalam ◽  
Tania Benedetti ◽  
...  
Keyword(s):  
Whole Blood ◽  
Blood Samples ◽  
Personal Glucose Meter ◽  
Glucose Meter ◽  
Whole Blood Samples

A glucose meter-based immunosensing platform that allows the quantification of procalcitonin in whole blood samples at clinically-relevant concentrations.

Enhanced 3D paper-based devices with a personal glucose meter for highly sensitive and portable biosensing of silver ion

2019 ◽  
Vol 137 ◽  
pp. 154-160 ◽  
Author(s):  
Wencheng Xiao ◽  
Yiming Gao ◽  
Yun Zhang ◽  
Jiao Li ◽  
Zhaoying Liu ◽  
...  
Keyword(s):  
Silver Ion ◽  
Personal Glucose Meter ◽  
Highly Sensitive ◽  
Glucose Meter
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