A novel competitive-displacement fluorescence assay for l-penicillamine based on the reaction between the target and N-acetyl-l-cysteine-capped CdTe quantum dots for copper ions

2018 ◽  
Vol 10 (19) ◽  
pp. 2263-2271 ◽  
Author(s):  
Yunmei Huang ◽  
Jidong Yang ◽  
Haiyan Yuan ◽  
Yuan Guo ◽  
Xiaoqing Zeng ◽  
...  

CdTe quantum dots (CdTe QDs) were modified by N-acetyl-l-cysteine (NALC) as novel fluorescent probes and successfully utilized for the determination of l-penicillamine.

2017 ◽  
Vol 41 (10) ◽  
pp. 4138-4144 ◽  
Author(s):  
Fanping Shi ◽  
Siyu Liu ◽  
Xingguang Su

A fluorescence assay for the sequential determination of lysozyme and trypsin was established based on l-cysteine capped CdTe quantum dots. Lysozyme with positive charges can interact with l-cysteine capped CdTe quantum dots. Lysozyme can be hydrolyzed into small fragments in the presence of trypsin, and the interaction between l-cysteine-capped CdTe QDs and lysozyme would be inhibited, which could be used for trypsin quantification.


2017 ◽  
Vol 9 (6) ◽  
pp. 929-936 ◽  
Author(s):  
Fan Zhang ◽  
Miaomiao Chen ◽  
Haiqing Zhang ◽  
Huayu Xiong ◽  
Wei Wen ◽  
...  

A sensitive, convenient and rapid fluorescent sensor for effectively and directly detecting propranolol was proposed based on the fluorescence suppression of 3-mercaptopropionic acid stabilized CdTe quantum dots.


RSC Advances ◽  
2015 ◽  
Vol 5 (55) ◽  
pp. 44173-44182 ◽  
Author(s):  
Xuanping Tan ◽  
Qin Li ◽  
Xiaoning Zhang ◽  
Yizhong Shen ◽  
Jidong Yang

A new fluorescence sensor for the determination of thioctic acid (TA) in aqueous media based on the recovered fluorescence of N-acetyl-l-cysteine capped CdTe quantum dots [NALC-CdTe QDs]–Cu2+ system was proposed.


Sensors ◽  
2018 ◽  
Vol 18 (8) ◽  
pp. 2605 ◽  
Author(s):  
Liyun Ding ◽  
Bing Xu ◽  
Tao Li ◽  
Jun Huang ◽  
Wei Bai

A novel “turn-on” fluorescent copper biosensor is developed successfully based on the graphene oxide (GO)-dsDNA-CdTe quantum dots (QDs) complex via chemical crosslink method. The optical and structure properties of GO-dsDNA-CdTe QDs complex are studied by fluorescence (FL) spectra and transmission electron microscopy (TEM) in detail. It is demonstrated that the fluorescence quenching of CdTe QDs is a process of fluorescence resonance energy transfer (FRET) due to the essential surface and quenching properties of two-dimensional GO. Copper ions induce the catalytic reaction of DNA chain and irreversibly break at the cleavage site, which will cause the G-quadruplex formation, moreover further result in the CdTe QDs separated from GO and restored its fluorescence. Therefore, a significant recovery effect on the fluorescence of the GO-dsDNA-CdTe QDs complex is observed in the presence of copper ions. The fluorescence responses are concentration-dependent and can be well described by a linear equation. Compared with other metal ions, the sensor performs good selectivity for copper ions.


Sensors ◽  
2019 ◽  
Vol 19 (20) ◽  
pp. 4548 ◽  
Author(s):  
Doris E. Ramírez-Herrera ◽  
Ana Patricia Reyes-Cruzaley ◽  
Giselle Dominguez ◽  
Francisco Paraguay-Delgado ◽  
Antonio Tirado-Guízar ◽  
...  

In this paper, we report the synthesis, characterization, and application of a new fluorescent nanosensor based on water-soluble CdTe quantum dots (QDs) coated with cysteamine (CA) for the determination of folic acid (FA). CdTe/CA QDs were characterized by high-resolution transmission electron microscopy, the zeta potential, and Fourier-transform infrared (FT-IR), UV-visible, and fluorescence spectroscopy. CdTe QDs coated with mercaptopropionic acid (MPA) and glutathione (GSH) were prepared for comparison purposes. The effect of FA on the photoluminescence intensity of the three thiol-capped QDs at pH 8 was studied. Only CdTe/CA QDs showed a notable fluorescence quenching in the presence of FA. Then, a nanosensor based on the fluorescence quenching of the CdTe QDs at pH 8 was explored. Under optimum conditions, the calibration curve showed a linear fluorescence quenching response in a concentration range of FA from 0.16 to 16.4 μM (R2 = 0.9944), with a detection limit of 0.048 μM. A probable mechanism of fluorescence quenching was proposed. The nanosensor showed good selectivity over other possible interferences. This method has been applied for FA quantification in orange beverage samples with excellent results (recoveries from 98.3 to 103.9%). The good selectivity, sensitivity, low cost, and rapidity make CdTe /CA QDs a suitable nanosensor for FA determination.


2021 ◽  
Author(s):  
Yifei Guo ◽  
Jingjing Du ◽  
Jianjun Li ◽  
Ran Yang ◽  
Peter B. de Harrington ◽  
...  

In this work, cysteamine-coated CdTe quantum dots (CA-CdTe QDs) were synthesized by a simple hydrothermal method employing cadmium chloride as the cadmium source and cysteamine hydrochloride as the functional monomer....


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